Abemaciclib is used to treat certain types of breast cancer. It belongs to a class of drugs known as kinase inhibitors.Reference standards of Abemaciclib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Abemaciclib
Catalogue No.:PA 54 15000
CAS :
Molecular Formula : C27H32F2N8
Molecular Weight : 506.61
Abemaciclib D8
Catalogue No.:PA STI 088914
Molecular Formula : C27H24D8F2N8
Molecular Weight : 514.65
N-(5-((4-(Ethyl-d5)piperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
Catalogue No.:PA 54 0151000
Molecular Formula : C27H27D5F2N8
Molecular Weight : 511.64
4-Fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Catalogue No.:PA 54 0151001
Molecular Formula : C11H13FN2
Molecular Weight : 192.24
6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)nicotinaldehyde
Catalogue No.:PA 54 0151002
Molecular Formula : C21H18F2N6O
Molecular Weight : 408.41
(6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol
Catalogue No.:PA 54 0151003
Molecular Formula : C21H20F2N6O
Molecular Weight : 410.43
N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-2-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-4-amine
Catalogue No.:PA 54 0151004
N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)pyrimidin-2-amine
Catalogue No.:PA 54 0151005
Molecular Formula : C42H44F4N12
Molecular Weight : 792.89
N,N'-((Piperazine-1,4-diylbis(methylene))bis(pyridine-5,2-diyl))bis(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine)
Catalogue No.:PA 54 0151006
Molecular Formula : C46H46F4N14
Molecular Weight : 870.97
1-Ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)methyl)pyridin-3-yl)methyl)piperazine 1,4-dioxide
Catalogue No.:PA 54 0151007
Molecular Formula : C28H33F2N7O2
Molecular Weight : 537.62
4-Ethyl-1-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)methyl)pyridin-3-yl)methyl)piperazine 1-oxide
Catalogue No.:PA 54 0151008
Molecular Formula : C28H33F2N7O
Molecular Weight : 521.62
1-Ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)methyl)pyridin-3-yl)methyl)piperazine 1-oxide
Catalogue No.:PA 54 0151009
N-(4-Bromo-2,6-difluorophenyl)-N'-isopropylacetimidamide
Catalogue No.:PA 54 0151010
Molecular Formula : C11H13BrF2N2
Molecular Weight : 291.14
6-(2-Chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
Catalogue No.:PA 54 0151011
Molecular Formula : C15H13ClF2N4
Molecular Weight : 322.74
(6-Aminopyridin-3-yl)(4-ethylpiperazin-1-yl)methanone
Catalogue No.:PA 54 0151012
Molecular Formula : C12H18N4O
Molecular Weight : 234.3
6-Chloro-5-fluoropyrimidin-2(1H)-one
Catalogue No.:PA 54 0151013
Molecular Formula : C4H2ClFN2O
Molecular Weight : 148.52
6-Bromo-4-fluoro-2-methyl-1-propyl-1H-benzo[d]imidazole
Catalogue No.:PA 54 0151014
Molecular Formula : C11H12BrFN2
Molecular Weight : 271.13
6-Bromo-1-ethyl-4-fluoro-2-methyl-1H-benzo[d]imidazole
Catalogue No.:PA 54 0151015
Molecular Formula : C10H10BrFN2
Molecular Weight : 257.11
Abemaciclib Metabolites M2
Catalogue No.:PA 54 0151016
Molecular Formula : C25H28F2N8
Molecular Weight : 478.55
N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)nitrous amide
Catalogue No.:PA 54 0151017
Molecular Formula : C27H31F2N9O
Molecular Weight : 535.6
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