Olaparib is used to treat ovarian cancer in people with a specific gene who have not improved or who have worsened after treatment with at least three other therapies.Reference standards of Olaparib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Olaparib
Catalogue No.:PA 15 70000
CAS :
Molecular Formula : C24H23FN4O3
Molecular Weight : 434.47
3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid
Catalogue No.:PA 15 70510
Molecular Formula : C16H12N2O3
Molecular Weight : 280.28
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 70520
Molecular Formula : C24H24N4O3
Molecular Weight : 416.48
Olaparib-D4
Catalogue No.:PA STI 089003
Molecular Formula : C24H19D4FN4O3
Molecular Weight : 438.5
4-(4-Fluoro-3-(4-(4-hydroxybutanoyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701000
Molecular Formula : C24H25FN4O4
Molecular Weight : 452.49
6-Chloro-4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701001
Molecular Formula : C24H22ClFN4O3
Molecular Weight : 468.91
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
Catalogue No.:PA 15 0701002
Molecular Formula : C10H11O5P
Molecular Weight : 242.17
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile
Catalogue No.:PA 15 0701003
Molecular Formula : C16H10FN3O
Molecular Weight : 279.27
4-Cyclopropanoylpiperazine-1-carboxylic Acid tert-Butyl Ester
Catalogue No.:PA 15 0701004
Molecular Formula : C13H22N2O3
Molecular Weight : 254.33
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
Catalogue No.:PA 15 0701005
Molecular Formula : C16H12FN3O2
Molecular Weight : 297.29
Tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate
Catalogue No.:PA 15 0701006
Molecular Formula : C25H27FN4O4
Molecular Weight : 466.51
4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701007
Molecular Formula : C20H19FN4O2
Molecular Weight : 366.4
4,4'-(((Piperazine-1,4-dicarbonyl)bis(4-fluoro-3,1-phenylene))bis(methylene))bis(phthalazin-1(2H)-one)
Catalogue No.:PA 15 0701008
Molecular Formula : C36H28F2N6O4
Molecular Weight : 646.65
4-(3-(4-Butyrylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701009
Molecular Formula : C24H25FN4O3
Molecular Weight : 436.49
1H-benzo[d][1,2,3]triazol-1-yl 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoate
Catalogue No.:PA 15 0701010
Molecular Formula : C22H14FN5O3
Molecular Weight : 415.38
2-Fluoro-N,N-dimethyl-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
Catalogue No.:PA 15 0701011
Molecular Formula : C18H16FN3O2
Molecular Weight : 325.34
(Z)-2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzoic acid
Catalogue No.:PA 15 0701012
Molecular Formula : C16H9FO4
Molecular Weight : 284.24
(Z)-3-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzylidene)isobenzofuran-1(3H)-one
Catalogue No.:PA 15 0701013
Molecular Formula : C24H21FN2O4
Molecular Weight : 420.44
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)-1,2-dihydrophthalazin-1-yl cyclopropanecarboxylate
Catalogue No.:PA 15 0701014
Molecular Formula : C28H29FN4O4
Molecular Weight : 504.56
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzoyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701015
Molecular Formula : C24H21FN4O4
Molecular Weight : 448.45
Piperazine-1,4-diylbis(cyclopropylmethanone)
Catalogue No.:PA 15 0701016
Molecular Formula : C12H18N2O2
Molecular Weight : 222.29
2-((Dimethoxyphosphoryl)((methoxy(3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphoryl)oxy)methyl)benzoic acid
Catalogue No.:PA 15 0701017
Molecular Formula : C19H20O10P2
Molecular Weight : 470.31
Cyclopropanecarbonyl Chloride
Catalogue No.:PA 15 0701018
Molecular Formula : C4H5ClO
Molecular Weight : 104.53
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
Catalogue No.:PA 15 0701019
Molecular Formula : C16H11FN2O3
Molecular Weight : 298.27
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-N-(5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-1H-indazol-3-yl)benzamide
Catalogue No.:PA 15 0701020
Molecular Formula : C32H22FN7O3
Molecular Weight : 571.57
4-((3-Hydroxy-1H-indazol-5-yl)methyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701021
Molecular Formula : C16H12N4O2
Molecular Weight : 292.3
Olaparib D5
Catalogue No.:PA STI 089147
Molecular Formula : C24H18D5FN4O3
Molecular Weight : 439.5
1,2-bis(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)ethane-1,2-dione
Catalogue No.:PA 15 0701022
Molecular Formula : C42H36F2N8O6
Molecular Weight : 786.8
4-(4-Fluoro-3-(4-nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701023
Molecular Formula : C20H18FN5O3
Molecular Weight : 395.39
4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carbaldehyde
Catalogue No.:PA 15 0701024
Molecular Formula : C21H19FN4O3
Molecular Weight : 394.41
4-(3-(4-Acetylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701025
Molecular Formula : C22H21FN4O3
Molecular Weight : 408.43
Methyl 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoate
Catalogue No.:PA 15 0701026
Molecular Formula : C17H13FN2O3
Molecular Weight : 312.3
4-((3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)(2-oxopyrrolidin-1-yl)methyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701027
Molecular Formula : C28H28FN5O4
Molecular Weight : 517.56
4-(5-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701028
4-(2-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701029
4-(4-Fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701030
Molecular Formula : C15H11FN2O
Molecular Weight : 254.26
4-(3-Bromo-4-fluorobenzyl)phthalazin-1(2H)-one
Catalogue No.:PA 15 0701031
Molecular Formula : C15H10BrFN2O
Molecular Weight : 333.16
(4-Fluoro-1,3-phenylene)bis((4-(cyclopropanecarbonyl)piperazin-1-yl)methanone)
Catalogue No.:PA 15 0701032
Molecular Formula : C24H29FN4O4
Molecular Weight : 456.52
(Z)-2-(2-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorophenyl)-1-hydrazineylvinyl)benzoic Acid
Catalogue No.:PA 15 0701033
1-(Cyclopropylmethyl)-4-nitrosopiperazine
Catalogue No.:PA 15 0701034
Molecular Formula : C8H15N3O
Molecular Weight : 169.23
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