alclometasone dipropionate and its Impurities
Alclometasone Dipropionate cream and ointment are indicated for the relief of corticosteroid-responsive dermatoses. It is a synthetic corticosteroid for topical dermatologic use, possessing anti-inflammatory, antipruritic, and vasoconstrictive properties. Reference standards of Alclometasone Dipropionate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2-((7R,8S,9S,10R,11S,13S,14S,16R,17R)-17-Acetoxy-7-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Propionate
2-((7R,8S,9S,10R,11S,13S,14S,16R,17R)-17-Acetoxy-7-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Propionate
Catalogue No.:PA 28 0091002
CAS :
NA
Molecular Formula : C27H35ClO7
Molecular Weight : 507.02
(Z)-2-((7R,10R,11S,13S,16R)-7-Chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-2-hydroxyacetaldehyde
(Z)-2-((7R,10R,11S,13S,16R)-7-Chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-2-hydroxyacetaldehyde
Catalogue No.:PA 28 0091004
CAS :
NA
Molecular Formula : C22H27ClO4
Molecular Weight : 390.9
(7R,10R,11S,13S,16R,17R)-7-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
(7R,10R,11S,13S,16R,17R)-7-Chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
Catalogue No.:PA 28 0091005
CAS :
NA
Molecular Formula : C25H33ClO6
Molecular Weight : 464.98
2-((7R,10R,11S,13S,16R,17R)-7-Chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl propionate
2-((7R,10R,11S,13S,16R,17R)-7-Chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl propionate
Catalogue No.:PA 28 0091006
CAS :
NA
Molecular Formula : C25H33ClO6
Molecular Weight : 464.98