ambrisentan and its Impurities
Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(R,S)-Ambrisentan acyl-β-D-glucuronide
(2S,3S,4S,5R)-6-((2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
Catalogue No.:PA 28 0461002
CAS :
1106685-82-8
Molecular Formula : C28H30N2O10
Molecular Weight : 554.55
(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
Catalogue No.:PA STI 088903
CAS :
NA
Molecular Formula : C22H19D3N2O5
Molecular Weight : 397.45