apatinib and its Impurities
Apatinib is a novel, small molecule, selective vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and is the second anti-angiogenic drug to be approved in China for the treatment of advanced or metastatic gastric cancer.Reference standards of Apatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.