It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma.. Reference standards of Cobimetinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Cobimetinib
Catalogue No.:PA 56 64000
CAS :
Molecular Formula : C21H21F3IN3O2
Molecular Weight : 531.31
Cobimetinib-d8
Catalogue No.:PA STI 022391
Molecular Formula : C21H13D8F3IN3O2
Molecular Weight : 539.37
Cobimetinib (racemate)
Catalogue No.:PA 56 0641000
Molecular Weight : 531.32
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