Eltrombopag-impurities | Pharmaffiliates

eltrombopag and its Impurities

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune thrombocytopenia when certain other medicines, or surgery to remove the spleen, have not worked well enough. It has been recently approved for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based therapy.. Reference standards of Eltrombopag API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 43 results for eltrombopag Impurities
PA 32 22000

Eltrombopag - API Standards

Eltrombopag

  • Catalogue No.:PA 32 22000

  • CAS :

    496775-61-2

  • Molecular Formula : C25H22N4O4

  • Molecular Weight : 442.47

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PA 32 22510

Eltrombopag Amide

Eltrombopag Amide

  • Catalogue No.:PA 32 22510

  • CAS :

    1246929-02-1

  • Molecular Formula : C25H23N5O3

  • Molecular Weight : 441.48

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PA 32 22520

Eltrombopag Ethyl Ester

Eltrombopag Ethyl Ester

  • Catalogue No.:PA 32 22520

  • CAS :

    NA

  • Molecular Formula : C27H26N4O4

  • Molecular Weight : 470.52

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PA 32 22530

Eltrombopag Methyl Ester

Eltrombopag Methyl Ester

  • Catalogue No.:PA 32 22530

  • CAS :

    1246929-01-0

  • Molecular Formula : C26H24N4O4

  • Molecular Weight : 456.49

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PA 32 22540

(E)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

(E)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 22540

  • CAS :

    NA

  • Molecular Formula : C25H21ClN4O5

  • Molecular Weight : 492.91

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PA 32 22550

1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one

1-(4-Ethoxyphenyl)-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H)-one

  • Catalogue No.:PA 32 22550

  • CAS :

    NA

  • Molecular Formula : C21H19NO5

  • Molecular Weight : 365.38

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PA 32 22560

(E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid

(E)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 22560

  • CAS :

    NA

  • Molecular Formula : C26H24N4O4

  • Molecular Weight : 456.49

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PA 32 22570

(Z)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

(Z)-5'-Chloro-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 22570

  • CAS :

    NA

  • Molecular Formula : C25H21ClN4O4

  • Molecular Weight : 476.91

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PA 32 22580

(Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid

(Z)-2'-(Benzyloxy)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 22580

  • CAS :

    NA

  • Molecular Formula : C32H28N4O4

  • Molecular Weight : 532.59

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PA STI 036900

Eltrombopag-13C4

Eltrombopag-13C4

  • Catalogue No.:PA STI 036900

  • CAS :

    1217230-31-3

  • Molecular Formula : C2113C4H22N4O4

  • Molecular Weight : 446.44

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PA 32 22590

3'-Amino-2'-Hydroxy-[1,1']biphenyl-3-carboxylic Acid

3'-Amino-2'-Hydroxy-[1,1']biphenyl-3-carboxylic Acid

  • Catalogue No.:PA 32 22590

  • CAS :

    376592-93-7

  • Molecular Formula : C13H11NO3

  • Molecular Weight : 229.23

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PA 32 0221000

(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

  • Catalogue No.:PA 32 0221000

  • CAS :

    NA

  • Molecular Formula : C25H21N5O5

  • Molecular Weight : 471.47

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PA 32 0221001

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221001

  • CAS :

    277299-70-4

  • Molecular Formula : C12H14N2O

  • Molecular Weight : 202.26

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PA 32 0221002

2-Aminoethyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate

2-Aminoethyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate

  • Catalogue No.:PA 32 0221002

  • CAS :

    NA

  • Molecular Formula : C28H29N5O4

  • Molecular Weight : 499.57

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PA 32 0221003

1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one

1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one

  • Catalogue No.:PA 32 0221003

  • CAS :

    18048-64-1

  • Molecular Formula : C12H14N2O

  • Molecular Weight : 202.26

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PA 32 0221004

Eltrombopag lactose adduct

Eltrombopag lactose adduct

  • Catalogue No.:PA 32 0221004

  • CAS :

    NA

  • Molecular Formula : C37H42N4O14

  • Molecular Weight : 766.76

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PA 32 0221005

(2S,3S,4S,5R)-6-((3-Acetamido-3'-carboxy-[1,1'-biphenyl]-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

(2S,3S,4S,5R)-6-((3-Acetamido-3'-carboxy-[1,1'-biphenyl]-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

  • Catalogue No.:PA 32 0221005

  • CAS :

    NA

  • Molecular Formula : C21H21NO10

  • Molecular Weight : 447.4

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PA 32 0221006

Methoxy Eltrombopag

Methoxy Eltrombopag

  • Catalogue No.:PA 32 0221006

  • CAS :

    1437383-35-1

  • Molecular Formula : C26H24N4O4

  • Molecular Weight : 456.5

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PA 32 0221007

(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-N-(2-hydroxyethyl)-[1,1'-biphenyl]-3-carboxamide

(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-N-(2-hydroxyethyl)-[1,1'-biphenyl]-3-carboxamide

  • Catalogue No.:PA 32 0221007

  • CAS :

    NA

  • Molecular Formula : C27H27N5O4

  • Molecular Weight : 485.54

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PA 32 0221009

2'-Hydroxybiphenyl-3-carboxylic Acid

2'-Hydroxybiphenyl-3-carboxylic Acid

  • Catalogue No.:PA 32 0221009

  • CAS :

    893736-72-6

  • Molecular Formula : C13H10O3

  • Molecular Weight : 214.22

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PA 32 0221008

Eltrombopag N-Oxide Impurity (E-Isomer)

Eltrombopag N-Oxide Impurity (E-Isomer)

  • Catalogue No.:PA 32 0221008

  • CAS :

    NA

  • Molecular Formula : C25H22N4O5

  • Molecular Weight : 458.47

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PA 32 0221010

2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid

2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 0221010

  • CAS :

    376591-95-6

  • Molecular Formula : C13H9NO5

  • Molecular Weight : 259.22

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PA 32 0221011

(E)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

(E)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221011

  • CAS :

    NA

  • Molecular Formula : C12H13N3O2

  • Molecular Weight : 231.26

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PA 32 0221012

Eltrombopag N-Oxide Impurity (Z-Isomer)

Eltrombopag N-Oxide Impurity (Z-Isomer)

  • Catalogue No.:PA 32 0221012

  • CAS :

    NA

  • Molecular Formula : C25H22N4O5

  • Molecular Weight : 458.47

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PA 32 0221013

N-Nitroso Eltrombopag Amino Impurity

N-Nitroso Eltrombopag Amino Impurity

  • Catalogue No.:PA 32 0221013

  • CAS :

    NA

  • Molecular Formula : C13H10N2O4

  • Molecular Weight : 258.23

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PA 32 0221014

3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 0221014

  • CAS :

    376591-99-0

  • Molecular Formula : C25H22N4O4

  • Molecular Weight : 442.48

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PA 32 0221015

1,1'',2'-Tris(3,4-dimethylphenyl)-5,5''-dihydroxy-3,3'',5'-trimethyl-1H,1''H-[4,4':4',4''-terpyrazol]-3'(2'H)-one

1,1'',2'-Tris(3,4-dimethylphenyl)-5,5''-dihydroxy-3,3'',5'-trimethyl-1H,1''H-[4,4':4',4''-terpyrazol]-3'(2'H)-one

  • Catalogue No.:PA 32 0221015

  • CAS :

    2750368-89-7

  • Molecular Formula : C36H38N6O3

  • Molecular Weight : 602.74

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PA STI 089437

Eltrombopag-d9

Eltrombopag-d9

  • Catalogue No.:PA STI 089437

  • CAS :

    NA

  • Molecular Formula : C25H13D9N4O4

  • Molecular Weight : 451.53

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PA 32 0221016

2-(2,3-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

2-(2,3-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221016

  • CAS :

    118048-94-5

  • Molecular Formula : C12H14N2O

  • Molecular Weight : 202.26

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PA 32 0221017

3,3'-(2-Amino-3-oxo-3H-phenoxazine-4,6-diyl)dibenzoic Acid

3,3'-(2-Amino-3-oxo-3H-phenoxazine-4,6-diyl)dibenzoic Acid

  • Catalogue No.:PA 32 0221017

  • CAS :

    1428987-69-2

  • Molecular Formula : C26H16N2O6

  • Molecular Weight : 452.42

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PA 32 0221018

Eltrombopag dimer-1 impurity

Eltrombopag dimer-1 impurity

  • Catalogue No.:PA 32 0221018

  • CAS :

    NA

  • Molecular Formula : C52H47N9O7

  • Molecular Weight : 910

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PA 32 0221019

2-(3,4-Dimethylphenyl)-5-methyl-1-nitroso-1,2-dihydro-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-5-methyl-1-nitroso-1,2-dihydro-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221019

  • CAS :

    NA

  • Molecular Formula : C12H13N3O2

  • Molecular Weight : 231.26

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PA 32 0221020

(Z)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

(Z)-2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221020

  • CAS :

    NA

  • Molecular Formula : C12H13N3O2

  • Molecular Weight : 231.26

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PA 32 0221022

 (Z)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime

(Z)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime

  • Catalogue No.:PA 32 0221022

  • CAS :

    NA

  • Molecular Formula : C12H15N3O

  • Molecular Weight : 217.27

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PA 32 0221021

 3'-(2-((4Z,5Z)-1-(3,4-Dimethylphenyl)-5-(hydroxyimino)-3-methyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

3'-(2-((4Z,5Z)-1-(3,4-Dimethylphenyl)-5-(hydroxyimino)-3-methyl-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 0221021

  • CAS :

    NA

  • Molecular Formula : C25H23N5O4

  • Molecular Weight : 457.49

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PAI 32 022001

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-hydroxyhydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

  • Catalogue No.:PAI 32 022001

  • CAS :

    NA

  • Molecular Formula : C26H24N4O5

  • Molecular Weight : 472.5

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PA 32 0221023

3'-Amino-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid

3'-Amino-2'-methoxy-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 0221023

  • CAS :

    1176777-76-6

  • Molecular Formula : C14H13NO3

  • Molecular Weight : 243.26

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PA 32 0221024

(E)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime

(E)-2-(3,4-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one oxime

  • Catalogue No.:PA 32 0221024

  • CAS :

    NA

  • Molecular Formula : C12H15N3O

  • Molecular Weight : 217.27

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PAI 32 022002

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazineyl)-2'-methoxy-[1,1'-biphenyl]-3-carboxylate

  • Catalogue No.:PAI 32 022002

  • CAS :

    NA

  • Molecular Formula : C27H26N4O4

  • Molecular Weight : 470.53

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PA 32 0221025

2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-4-(hydroxyimino)-5-methyl-2,4-dihydro-3H-pyrazol-3-one

  • Catalogue No.:PA 32 0221025

  • CAS :

    NA

  • Molecular Formula : C12H13N3O2

  • Molecular Weight : 231.26

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PA 32 0221026

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

Methyl (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)-1-nitrosohydrazineyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

  • Catalogue No.:PA 32 0221026

  • CAS :

    NA

  • Molecular Formula : C26H23N5O5

  • Molecular Weight : 485.5

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PA 32 0221027

(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid

(Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-5'-nitroso-[1,1'-biphenyl]-3-carboxylic Acid

  • Catalogue No.:PA 32 0221027

  • CAS :

    NA

  • Molecular Formula : C25H21N5O5

  • Molecular Weight : 471.47

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PA 32 0221028

(E)-Eltrombopag

(E)-Eltrombopag

  • Catalogue No.:PA 32 0221028

  • CAS :

    NA

  • Molecular Formula : C25H22N4O4

  • Molecular Weight : 442.48

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