fusidic acid and its Impurities
An antibiotic which is derived from fungus Fusidium coccineum , Fusidic acid is bacteriostatic in nature. It works by preventing the protein synthesis. It shows action against both gram positive and gram negative strains. Reference standards of Fusidic Acid API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(Z)-2-((3R,4S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-4-(3,3-dimethyloxiran-2-yl)butanoic acid,
(Z)-2-((3R,4S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-4-(3,3-dimethyloxiran-2-yl)butanoic acid,
Catalogue No.:PAI 06 014210
CAS :
NA
Molecular Formula : C31H48O7
Molecular Weight : 532.72
(5S,Z)-2-((3R,4S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-5,6-dihydroxy-6-methylheptanoic acid,
(5S,Z)-2-((3R,4S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-5,6-dihydroxy-6-methylheptanoic acid,
Catalogue No.:PAI 06 014220
CAS :
NA
Molecular Formula : C31H50O8
Molecular Weight : 550.73
(Z)-Tetrahydro-2H-pyran-2-yl 2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-11-hydroxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)dodecahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoate
(Z)-Tetrahydro-2H-pyran-2-yl 2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-11-hydroxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)dodecahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoate
Catalogue No.:PAI 06 014221
CAS :
NA
Molecular Formula : C41H64O8
Molecular Weight : 684.96
(Z)-tetrahydro-2H-pyran-2-yl 2-((3R,4S,5S,8R,10S,13R,14S,16S)-16-acetoxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-3,4,5,6,7,8,12,13,15,16-decahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoate
(Z)-tetrahydro-2H-pyran-2-yl 2-((3R,4S,5S,8R,10S,13R,14S,16S)-16-acetoxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-3,4,5,6,7,8,12,13,15,16-decahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoate
Catalogue No.:PAI 06 014222
CAS :
NA
Molecular Formula : C41H62O7
Molecular Weight : 666.94
(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((R)-6-iodo-7,7-dimethyl-2-oxooxepan-3-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl Acetate
(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((R)-6-iodo-7,7-dimethyl-2-oxooxepan-3-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl Acetate
Catalogue No.:PAI 06 014223
CAS :
NA
Molecular Formula : C31H47IO6
Molecular Weight : 642.62
Benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
Benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
Catalogue No.:PAI 06 014224
CAS :
NA
Molecular Formula : C38H54O6
Molecular Weight : 606.84
Benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-11-hydroxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
Benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-11-hydroxy-4,8,10,14-tetramethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
Catalogue No.:PAI 06 014225
CAS :
NA
Molecular Formula : C43H62O7
Molecular Weight : 690.96
benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-4,8,10,14-tetramethyl-11-((methylsulfonyl)oxy)-3-((tetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
benzyl (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-4,8,10,14-tetramethyl-11-((methylsulfonyl)oxy)-3-((tetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylhept-5-enoate
Catalogue No.:PAI 06 014226
CAS :
NA
Molecular Formula : C44H64O9S
Molecular Weight : 769.05
(Z)-2-((3R,4S,5S,8R,10S,13R,14S)-16-Acetoxy-3-hydroxy-4,8,10,14-tetramethyl-1,2,3,4,5,6,7,8,10,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylheptanoic acid
(Z)-2-((3R,4S,5S,8R,10S,13R,14S)-16-Acetoxy-3-hydroxy-4,8,10,14-tetramethyl-1,2,3,4,5,6,7,8,10,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-6-methylheptanoic acid
Catalogue No.:PAI 06 014227
CAS :
NA
Molecular Formula : C31H48O5
Molecular Weight : 500.72