panobinostat and its Impurities

Panobinostat is used in combination with the anti-cancer drug bortezomib and the corticoid dexamethasone for the treatment of multiple myeloma in adults who had received at least two previous treatments, including bortezomib and an immunomodulatory agent. It is a drug by Novartis for the treatment of various cancers.Reference standards of Panobinostat API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.