Proxibarbital and its Impurities

Proxibarbital is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action. It was also used in the treatment of migraine headaches in a similar manner to butalbital. Reference standards of Proxibarbital API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.