Ruxolitinib is used to treat myelofibrosis or polycythemia vera, which are bone marrow disorders that that affect your body's ability to produce blood cells. Reference standards of Ruxolitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
rac-Ruxolitinib-13C,15N2
Catalogue No.:PA STI 078620
CAS :
Molecular Formula : C1613CH18N415N2
Molecular Weight : 309.34
rac-Ruxolitinib-d8
Catalogue No.:PA STI 078630
Molecular Formula : C17H10D8N6
Molecular Weight : 314.41
Ruxolitinib
Catalogue No.:PA 18 82000
Molecular Formula : C17H18N6
Molecular Weight : 306.37
Ruxolitinib-amide
Catalogue No.:PA 18 0821000
Molecular Formula : C17H20N6O
Molecular Weight : 324.39
(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanamide
Catalogue No.:PA 18 0821001
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 18 0821002
Molecular Formula : C15H21N5OSi
Molecular Weight : 315.45
3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PA 18 0821003
Molecular Formula : C23H32N6OSi
Molecular Weight : 436.64
(S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Catalogue No.:PA 18 0821004
(R)-4-Amino-6-(1-(2-cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)pyrimidine-5-carboxylic Acid
Catalogue No.:PA 18 0821005
Molecular Formula : C16H18N6O2
Molecular Weight : 326.36
(R)-3-(4-(6-Amino-5-formylpyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Catalogue No.:PA 18 0821006
Molecular Formula : C16H18N6O
Molecular Weight : 310.36
3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid
Catalogue No.:PA 18 0821007
Molecular Formula : C17H19N5O2
Molecular Weight : 325.37
(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid
Catalogue No.:PA 18 0821008
(R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Catalogue No.:PA 18 0821009
Molecular Formula : C11H14BrN3
Molecular Weight : 268.16
(R)-3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PA 18 0821010
Molecular Formula : C17H17N7O
Molecular Weight : 335.37
(3R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxycyclopentyl)propanenitrile
Catalogue No.:PA 18 0821011
Molecular Formula : C17H18N6O
Molecular Weight : 322.37
(R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 1-oxide
Catalogue No.:PA 18 0821012
(R)-4-(1-(2-Cyano-1-cyclopentylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine 3-oxide
Catalogue No.:PA 18 0821013
Methyl (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanoate
Catalogue No.:PA 18 0821014
Molecular Formula : C18H21N5O2
Molecular Weight : 339.4
Ruxolitinib Hydroxy Pyrimidine Impurity
Catalogue No.:PA 18 0821015
Molecular Formula : C18H20N6O
Molecular Weight : 336.4
(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PA 18 0821016
Ruxolitinib Acetamide Impurity
Catalogue No.:PA 18 0821017
Molecular Formula : C20H23N7O
Molecular Weight : 377.45
7-Nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-ol
Catalogue No.:PA 18 0821018
Molecular Formula : C6H4N4O2
Molecular Weight : 164.12
4-(1-Nitroso-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 18 0821019
Molecular Formula : C15H20N6O2Si
Molecular Weight : 344.45
Ruxolitinib N-Methanol
Catalogue No.:PA 18 0821020
3-Cyclopentyl-3-(4-(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanamide
Catalogue No.:PA 18 0821021
Molecular Formula : C17H19N7O2
Molecular Weight : 353.39
Ruxolitinib M18 Metabolite
Catalogue No.:PA 18 0821022
(+)-Di-p-anisoyl-D-tartaric Acid
Catalogue No.:PA 18 0821023
Molecular Formula : C20H18O10
Molecular Weight : 418.35
3-Cyclopentylacrylonitrile
Catalogue No.:PA 18 0821024
Molecular Formula : C8H11N
Molecular Weight : 121.18
rac-Ruxolitinib-d9
Catalogue No.:PA STI 089499
Molecular Formula : C17H9D9N6
Molecular Weight : 315.43
(R)-3-Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile (2S,3S)-2,3-bis(benzoyloxy)succinate
Catalogue No.:PA 18 0821025
Molecular Formula : C41H46N6O9Si
Molecular Weight : 794.94
3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PA 18 0821026
Molecular Formula : C17H26BN3O2
Molecular Weight : 315.22
Methyl (E)-3-cyclopentylacrylate
Catalogue No.:PAI 18 082001
Molecular Formula : C9H14O2
Molecular Weight : 154.21
Methyl 3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanoate
Catalogue No.:PAI 18 082002
Molecular Formula : C12H17BrN2O2
Molecular Weight : 301.18
3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanoic Acid
Catalogue No.:PAI 18 082003
Molecular Formula : C11H15BrN2O2
Molecular Weight : 287.16
(R)-4-Benzyl-3-((R)-3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanoyl)oxazolidin-2-one
Catalogue No.:PAI 18 082004
Molecular Formula : C21H24BrN3O3
Molecular Weight : 446.35
(R)-4-Benzyl-3-((S)-3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanoyl)oxazolidin-2-one
Catalogue No.:PAI 18 082005
(S)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanamide
Catalogue No.:PAI 18 082006
Molecular Formula : C11H16BrN3O
Molecular Weight : 286.17
(S)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Catalogue No.:PAI 18 082007
(S)-3-Cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PAI 18 082008
3-Cyclopentyl-3-(4-(5-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
Catalogue No.:PA 18 0821027
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