Tolvaptan-impurities | Pharmaffiliates

tolvaptan and its Impurities

Tolvaptan is used to treat hyponatremia associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone. It is an aquaretic drug.Reference standards of Tolvaptan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 49 results for tolvaptan Impurities
PA 20 98000

Tolvaptan - API Standards

Tolvaptan

  • Catalogue No.:PA 20 98000

  • CAS :

    150683-30-0

  • Molecular Formula : C26H25ClN2O3

  • Molecular Weight : 448.94

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PA 20 98510

2-Methyl-4-(2-methylbenzoylamino)-benzoic Acid

2-Methyl-4-(2-methylbenzoylamino)-benzoic Acid

  • Catalogue No.:PA 20 98510

  • CAS :

    317374-08-6

  • Molecular Formula : C16H15NO3

  • Molecular Weight : 269.3

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PA 20 98520

N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 98520

  • CAS :

    1432725-23-9

  • Molecular Formula : C26H26N2O3

  • Molecular Weight : 414.5

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PA 20 98530

(4-Amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone

(4-Amino-2-methylphenyl)(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methanone

  • Catalogue No.:PA 20 98530

  • CAS :

    1432725-24-0

  • Molecular Formula : C18H19ClN2O2

  • Molecular Weight : 330.81

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PA 20 98540

5-Dehydro Tolvaptan

5-Dehydro Tolvaptan

  • Catalogue No.:PA 20 98540

  • CAS :

    137973-76-3

  • Molecular Formula : C26H23ClN2O3

  • Molecular Weight : 446.93

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PA 20 98550

7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one

7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one

  • Catalogue No.:PA 20 98550

  • CAS :

    137982-91-3

  • Molecular Formula : C18H15ClN2O4

  • Molecular Weight : 358.78

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PA 20 98560

1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one

1,2,3,4-Tetrahydro-1-(4-Amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one

  • Catalogue No.:PA 20 98560

  • CAS :

    137977-97-0

  • Molecular Formula : C18H17ClN2O2

  • Molecular Weight : 328.79

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PA 20 98570

N-(4-(7-Chloro-4-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

N-(4-(7-Chloro-4-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 98570

  • CAS :

    NA

  • Molecular Formula : C27H25ClN2O3

  • Molecular Weight : 460.95

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PA STI 083840

Tolvaptan-d7

Tolvaptan-d7

  • Catalogue No.:PA STI 083840

  • CAS :

    1246818-18-7

  • Molecular Formula : C26H18D7ClN2O3

  • Molecular Weight : 455.98

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Tolvaptan (IPRS/93/13)-from IPC

  • Catalogue No.:PA IPIPRS 93 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

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PA 20 0981000

7-Bromo Tolvaptan

7-Bromo Tolvaptan

  • Catalogue No.:PA 20 0981000

  • CAS :

    2921676-63-1

  • Molecular Formula : C26H25BrN2O3

  • Molecular Weight : 493.4

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PA 20 0981001

(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(2-methyl-4-nitrophenyl)methanone

(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)(2-methyl-4-nitrophenyl)methanone

  • Catalogue No.:PA 20 0981001

  • CAS :

    NA

  • Molecular Formula : C18H17ClN2O4

  • Molecular Weight : 360.79

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PA 20 0981002

7-Chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

7-Chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

  • Catalogue No.:PA 20 0981002

  • CAS :

    160129-45-3

  • Molecular Formula : C10H10ClNO

  • Molecular Weight : 195.65

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PA 20 0981003

4-(5-Chloro-2-(3-methyl-5-(2-methylbenzamido)benzamido)phenyl)-4-hydroxybutanoic acid

4-(5-Chloro-2-(3-methyl-5-(2-methylbenzamido)benzamido)phenyl)-4-hydroxybutanoic acid

  • Catalogue No.:PA 20 0981003

  • CAS :

    NA

  • Molecular Formula : C26H25ClN2O5

  • Molecular Weight : 480.95

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PA 20 0981006

N-(4-Chloro-2-(1,4-dihydroxybutyl)phenyl)-2-methyl-4-(2-methylbenzamido)benzamide

N-(4-Chloro-2-(1,4-dihydroxybutyl)phenyl)-2-methyl-4-(2-methylbenzamido)benzamide

  • Catalogue No.:PA 20 0981006

  • CAS :

    1587638-01-4

  • Molecular Formula : C26H27ClN2O4

  • Molecular Weight : 466.96

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PA 20 0981007

N-(4-Chloro-2-(4-hydroxybutanoyl)phenyl)-2-methyl-4-(2-methylbenzamido)benzamide

N-(4-Chloro-2-(4-hydroxybutanoyl)phenyl)-2-methyl-4-(2-methylbenzamido)benzamide

  • Catalogue No.:PA 20 0981007

  • CAS :

    1587638-02-5

  • Molecular Formula : C26H25ClN2O4

  • Molecular Weight : 464.95

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PA 20 0981008

(R)-(+)-Tolvaptan

(R)-(+)-Tolvaptan

  • Catalogue No.:PA 20 0981008

  • CAS :

    331947-66-1

  • Molecular Formula : C26H25ClN2O3

  • Molecular Weight : 448.95

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PA 20 0981009

(S)-(-)-Tolvaptan

(S)-(-)-Tolvaptan

  • Catalogue No.:PA 20 0981009

  • CAS :

    331947-44-5

  • Molecular Formula : C26H25ClN2O3

  • Molecular Weight : 448.95

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PA 20 0981010

Tolvaptan γ-oxobutanoic acid impurity

Tolvaptan γ-oxobutanoic acid impurity

  • Catalogue No.:PA 20 0981010

  • CAS :

    1346599-56-1

  • Molecular Formula : C26H23ClN2O5

  • Molecular Weight : 478.93

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PA 20 0981011

Tolvaptan γ-hydroxybutanoic acid impurity

Tolvaptan γ-hydroxybutanoic acid impurity

  • Catalogue No.:PA 20 0981011

  • CAS :

    1346599-75-4

  • Molecular Formula : C26H25ClN2O5

  • Molecular Weight : 480.95

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PA 20 0981012

7-Chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-(2-methylbenzamido)benzoate

7-Chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3-dihydro-1H-benzo[b]azepin-5-yl 2-methyl-4-(2-methylbenzamido)benzoate

  • Catalogue No.:PA 20 0981012

  • CAS :

    1580889-36-6

  • Molecular Formula : C42H36ClN3O5

  • Molecular Weight : 698.22

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PA 20 0981013

2-Methyl-4-nitrobenzoyl chloride

2-Methyl-4-nitrobenzoyl chloride

  • Catalogue No.:PA 20 0981013

  • CAS :

    30459-70-2

  • Molecular Formula : C8H6ClNO3

  • Molecular Weight : 199.59

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PA 20 0981014

7-Chloro-4-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine

7-Chloro-4-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine

  • Catalogue No.:PA 20 0981014

  • CAS :

    1863916-82-8

  • Molecular Formula : C11H14ClNO

  • Molecular Weight : 211.69

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PA 20 0981004

7-Chloro-1-nitroso-2,3,4,5-tetrahydro-1-benzazepin-5-ol

7-Chloro-1-nitroso-2,3,4,5-tetrahydro-1-benzazepin-5-ol

  • Catalogue No.:PA 20 0981004

  • CAS :

    NA

  • Molecular Formula : C10H11ClN2O2

  • Molecular Weight : 226.66

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PA 20 0981005

1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol

1-[4-(Benzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol

  • Catalogue No.:PA 20 0981005

  • CAS :

    1580889-33-3

  • Molecular Formula : C25H23ClN2O3

  • Molecular Weight : 434.92

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PA 20 0981015

4-(5-Chloro-2-(3-methyl-5-(2-methylbenzamido)benzamido)phenyl)-4-oxobutanoic acid

4-(5-Chloro-2-(3-methyl-5-(2-methylbenzamido)benzamido)phenyl)-4-oxobutanoic acid

  • Catalogue No.:PA 20 0981015

  • CAS :

    NA

  • Molecular Formula : C26H23ClN2O5

  • Molecular Weight : 478.93

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PA 20 0981016

N-(4-(7-Chloro-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

N-(4-(7-Chloro-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981016

  • CAS :

    176970-21-1

  • Molecular Formula : C26H23ClN2O2

  • Molecular Weight : 430.93

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PA 20 0981017

7-Chloro-2,3-dihydro-1H-benzo[b]azepine

7-Chloro-2,3-dihydro-1H-benzo[b]azepine

  • Catalogue No.:PA 20 0981017

  • CAS :

    1316312-24-9

  • Molecular Formula : C10H10ClN

  • Molecular Weight : 179.65

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PA 20 0981018

N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

N-(4-(5-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981018

  • CAS :

    150681-19-9

  • Molecular Formula : C25H24N2O3

  • Molecular Weight : 400.48

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PA 20 0981019

N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981019

  • CAS :

    150683-27-5

  • Molecular Formula : C25H23ClN2O3

  • Molecular Weight : 434.92

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PA 20 0981020

2-Desmethyl-4-methyl Tolvaptan

2-Desmethyl-4-methyl Tolvaptan

  • Catalogue No.:PA 20 0981020

  • CAS :

    1580889-25-3

  • Molecular Formula : C26H25ClN2O3

  • Molecular Weight : 448.95

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PA 20 0981022

7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol

7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol

  • Catalogue No.:PA 20 0981022

  • CAS :

    1310357-40-4

  • Molecular Formula : C10H12ClNO

  • Molecular Weight : 197.66

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PA 20 0981021

Methyl 2-methyl-4-(2-methylbenzamido)benzoate

Methyl 2-methyl-4-(2-methylbenzamido)benzoate

  • Catalogue No.:PA 20 0981021

  • CAS :

    1118884-66-4

  • Molecular Formula : C17H17NO3

  • Molecular Weight : 283.33

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PA 20 0981023

N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-3-methylbenzamide

N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-3-methylbenzamide

  • Catalogue No.:PA 20 0981023

  • CAS :

    1580889-27-5

  • Molecular Formula : C26H25ClN2O3

  • Molecular Weight : 448.95

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PA 20 0981024

N-(4-(7-Chloro-5-methoxy-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

N-(4-(7-Chloro-5-methoxy-2,3-dihydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981024

  • CAS :

    2468638-31-3

  • Molecular Formula : C27H25ClN2O3

  • Molecular Weight : 460.96

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PA 20 0981025

7-Chloro-5-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine

7-Chloro-5-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine

  • Catalogue No.:PA 20 0981025

  • CAS :

    1824346-18-0

  • Molecular Formula : C11H14ClNO

  • Molecular Weight : 211.69

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PA 20 0981026

(4-Amino-2-methylphenyl)(7-chloro-2,3-dihydro-1H-benzo[b]azepin-1-yl)methanone

(4-Amino-2-methylphenyl)(7-chloro-2,3-dihydro-1H-benzo[b]azepin-1-yl)methanone

  • Catalogue No.:PA 20 0981026

  • CAS :

    1859917-22-8

  • Molecular Formula : C18H17ClN2O

  • Molecular Weight : 312.8

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PA 20 0981027

N-(4-(5-Hydroxy-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

N-(4-(5-Hydroxy-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981027

  • CAS :

    1859917-54-6

  • Molecular Formula : C27H28N2O4

  • Molecular Weight : 444.53

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Tolvaptan (IPRST001)

Tolvaptan (IPRST001)

  • Catalogue No.:PA IPRST001

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 20 0981028

2-Methyl-4-nitrobenzoic Acid

2-Methyl-4-nitrobenzoic Acid

  • Catalogue No.:PA 20 0981028

  • CAS :

    1975-51-5

  • Molecular Formula : C8H7NO4

  • Molecular Weight : 181.15

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PA 20 0981029

2-Methyl-4-(2-methylbenzamido)benzoyl Chloride

2-Methyl-4-(2-methylbenzamido)benzoyl Chloride

  • Catalogue No.:PA 20 0981029

  • CAS :

    331947-69-4

  • Molecular Formula : C16H14ClNO2

  • Molecular Weight : 287.74

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PA 20 0981030

N-(4-Acetyl-3-methylphenyl)-2-methylbenzamide

N-(4-Acetyl-3-methylphenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981030

  • CAS :

    928151-34-2

  • Molecular Formula : C17H17NO2

  • Molecular Weight : 267.33

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PA 20 0981031

2-Methyl-N-(m-tolyl)benzamide

2-Methyl-N-(m-tolyl)benzamide

  • Catalogue No.:PA 20 0981031

  • CAS :

    56776-45-5

  • Molecular Formula : C15H15NO

  • Molecular Weight : 225.29

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PA 20 0981032

7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one

  • Catalogue No.:PA 20 0981032

  • CAS :

    193686-76-9

  • Molecular Formula : C17H16ClNO3S

  • Molecular Weight : 349.83

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PA 20 0981033

Methyl 5-chloro-2-((N-(4-ethoxy-4-oxobutyl)-4-methylphenyl)sulfonamido)benzoate

Methyl 5-chloro-2-((N-(4-ethoxy-4-oxobutyl)-4-methylphenyl)sulfonamido)benzoate

  • Catalogue No.:PA 20 0981033

  • CAS :

    247237-43-0

  • Molecular Formula : C21H24ClNO6S

  • Molecular Weight : 453.93

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PA 20 0981034

Methyl 5-chloro-2-((4-methylphenyl)sulfonamido)benzoate

Methyl 5-chloro-2-((4-methylphenyl)sulfonamido)benzoate

  • Catalogue No.:PA 20 0981034

  • CAS :

    247237-38-3

  • Molecular Formula : C15H14ClNO4S

  • Molecular Weight : 339.79

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PA 20 0981035

Methyl 2-amino-5-chlorobenzoate

Methyl 2-amino-5-chlorobenzoate

  • Catalogue No.:PA 20 0981035

  • CAS :

    5202-89-1

  • Molecular Formula : C8H8ClNO2

  • Molecular Weight : 185.61

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PA 20 0981036

Methyl 5-chloro-2-nitrobenzoate

Methyl 5-chloro-2-nitrobenzoate

  • Catalogue No.:PA 20 0981036

  • CAS :

    51282-49-6

  • Molecular Formula : C8H6ClNO4

  • Molecular Weight : 215.59

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PA 20 0981037

(R)-N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

(R)-N-(4-(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide

  • Catalogue No.:PA 20 0981037

  • CAS :

    2376909-00-9

  • Molecular Formula : C25H23ClN2O3

  • Molecular Weight : 434.92

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