| Catalogue number: | PA STI 014220 |
| Chemical name: | (1R,2R)-Bortezomib-d5 |
CAS Number: |
NA |
| Alternate CAS Number: | 1132709-15-9 (Unlabeled) |
| Category: | chiral standards,boron derivatives,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes |
| Synonyms: | B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic-d5 Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic-d5 Acid; |
| Molecular form: | C19H20D5BN4O4 |
| Appearance: | NA |
| Mol. Weight: | 389.27 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Labelled (1R,2R)-Bortezomib is a diastereomer of Bortezomib, the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway |
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