Nilotinib-impurities | Pharmaffiliates

nilotinib

Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Nilotinib - Impurity C
    [catalogue_number] => PA 14 64520
    [category_ids] => 80,79,71
    [chemical_name] => 
    [weight] => 151.16
    [form] => C8H9NO2
    [cas] => 2458-12-0
    [pslug] => 2458-12-0-nilotinib-impurity-c-pa1464520
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PA 14 64520

Nilotinib - Impurity C


  • Catalogue No.:PA 14 64520

  • CAS :

    2458-12-0

  • Molecular Formula : C8H9NO2

  • Molecular Weight : 151.16

stdClass Object
(
    [pname] => 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
    [catalogue_number] => PA 14 64530
    [category_ids] => ,79,80,70,84,
    [chemical_name] => 
    [weight] => 241.21
    [form] => C11H10F3N3
    [cas] => 641571-16-6
    [pslug] => 641571-16-6-3-5-methyl-1h-imidazol-1-yl-5-trifluoromethyl-benzenamine-pa1464530
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PA 14 64530

3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine


  • Catalogue No.:PA 14 64530

  • CAS :

    641571-16-6

  • Molecular Formula : C11H10F3N3

  • Molecular Weight : 241.21

stdClass Object
(
    [pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
    [catalogue_number] => PA 14 64540
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 271.2
    [form] => C11H8F3N3O2
    [cas] => 916975-92-3
    [pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540
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PA 14 64540

4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole


  • Catalogue No.:PA 14 64540

  • CAS :

    916975-92-3

  • Molecular Formula : C11H8F3N3O2

  • Molecular Weight : 271.2

stdClass Object
(
    [pname] => Nilotinib - Impurity H (Hydrochloride Salt)
    [catalogue_number] => PA 14 64550
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 565.98
    [form] => C28H23ClF3N7O
    [cas] => NA
    [pslug] => -nilotinib-impurity-h-hydrochloride-salt-pa1464550
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PA 14 64550

Nilotinib - Impurity H (Hydrochloride Salt)


  • Catalogue No.:PA 14 64550

  • CAS :

    NA

  • Molecular Formula : C28H23ClF3N7O

  • Molecular Weight : 565.98

stdClass Object
(
    [pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 64560
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 563.96
    [form] => C28H21ClF3N7O
    [cas] => NA
    [pslug] => 3-4-chloro-6-pyridin-3-yl-pyrimidin-2-yl-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa1464560
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PA 14 64560

3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 14 64560

  • CAS :

    NA

  • Molecular Formula : C28H21ClF3N7O

  • Molecular Weight : 563.96

stdClass Object
(
    [pname] => Nilotinib - Impurity H (Freebase)
    [catalogue_number] => PA 14 64570
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 529.52
    [form] => C28H22F3N7O
    [cas] => 641571-15-5
    [pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570
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PA 14 64570

Nilotinib - Impurity H (Freebase)


  • Catalogue No.:PA 14 64570

  • CAS :

    641571-15-5

  • Molecular Formula : C28H22F3N7O

  • Molecular Weight : 529.52

stdClass Object
(
    [pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
    [catalogue_number] => PA 14 64580
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 291.7
    [form] => C12H13ClF3N3
    [cas] => NA
    [pslug] => 3-4-ethyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-hydrochloride-pa1464580
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PA 14 64580

3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride


  • Catalogue No.:PA 14 64580

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3N3

  • Molecular Weight : 291.7

stdClass Object
(
    [pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 64590
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 227.19
    [form] => C10H8F3N3
    [cas] => 943320-48-7
    [pslug] => 943320-48-7-3-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa1464590
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PA 14 64590

3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline


  • Catalogue No.:PA 14 64590

  • CAS :

    943320-48-7

  • Molecular Formula : C10H8F3N3

  • Molecular Weight : 227.19

stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
    [catalogue_number] => PA STI 062190
    [category_ids] => ,79,80,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 244.23
    [form] => C11H7D3F3N3
    [cas] => 1246815-34-8
    [pslug] => 1246815-34-8-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethylaniline-d3-pasti062190
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PA STI 062190

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3


  • Catalogue No.:PA STI 062190

  • CAS :

    1246815-34-8

  • Molecular Formula : C11H7D3F3N3

  • Molecular Weight : 244.23