Ambrisentan-Impurities | Pharmaffiliates

ambrisentan

Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Ambrisentan - API Standards 
    [catalogue_number] => PA 28 46000
    [category_ids] => 82,80,78,71,70
    [chemical_name] => 
    [weight] => 378.42
    [form] => C22H22N2O4
    [cas] => 177036-94-1
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PA 28 46000

Ambrisentan - API Standards


  • Catalogue No.:PA 28 46000

  • CAS :

    177036-94-1

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.42

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stdClass Object
(
    [pname] => Ambrisentan Vinyloxy Impurity
    [catalogue_number] => PA 28 46550
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 302.37
    [form] => C20H18N2O
    [cas] => 1639429-81-4
    [pslug] => 1639429-81-4-ambrisentan-vinyloxy-impurity-pa2846550
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    [offers_product_code] => PA 28 46550
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PA 28 46550

Ambrisentan Vinyloxy Impurity


  • Catalogue No.:PA 28 46550

  • CAS :

    1639429-81-4

  • Molecular Formula : C20H18N2O

  • Molecular Weight : 302.37

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stdClass Object
(
    [pname] => 2-Hydroxy-4,6-dimethyl Pyrimidine
    [catalogue_number] => PA 28 46580
    [category_ids] => ,80,84,79,
    [chemical_name] => 
    [weight] => 124.14
    [form] => C6H8N2O
    [cas] => 108-79-2
    [pslug] => 108-79-2-2-hydroxy-4-6-dimethyl-pyrimidine-pa2846580
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PA 28 46580

2-Hydroxy-4,6-dimethyl Pyrimidine


  • Catalogue No.:PA 28 46580

  • CAS :

    108-79-2

  • Molecular Formula : C6H8N2O

  • Molecular Weight : 124.14

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stdClass Object
(
    [pname] => rac Ambrisentan
    [catalogue_number] => PA 28 46590
    [category_ids] => ,80,71,78,
    [chemical_name] => 
    [weight] => 378.42
    [form] => C22H22N2O4
    [cas] => 713516-99-5
    [pslug] => 713516-99-5-rac-ambrisentan-pa2846590
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PA 28 46590

rac Ambrisentan


  • Catalogue No.:PA 28 46590

  • CAS :

    713516-99-5

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.42

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stdClass Object
(
    [pname] => 4,6-Dimethyl-2-(methylsulfonyl)pyrimidine
    [catalogue_number] => PA 28 46510
    [category_ids] => ,80,84,88,
    [chemical_name] => 
    [weight] => 186.23
    [form] => C7H10N2O2S
    [cas] => 35144-22-0
    [pslug] => 35144-22-0-4-6-dimethyl-2-methylsulfonyl-pyrimidine-pa2846510
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PA 28 46510

4,6-Dimethyl-2-(methylsulfonyl)pyrimidine


  • Catalogue No.:PA 28 46510

  • CAS :

    35144-22-0

  • Molecular Formula : C7H10N2O2S

  • Molecular Weight : 186.23

stdClass Object
(
    [pname] => (S)-Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate
    [catalogue_number] => PA 28 46530
    [category_ids] => ,80,84,
    [chemical_name] => 
    [weight] => 286.32
    [form] => C17H18O4
    [cas] => 177036-78-1
    [pslug] => 177036-78-1-s-methyl-2-hydroxy-3-methoxy-3-3-diphenylpropanoate-pa2846530
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PA 28 46530

(S)-Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PA 28 46530

  • CAS :

    177036-78-1

  • Molecular Formula : C17H18O4

  • Molecular Weight : 286.32

stdClass Object
(
    [pname] => Ambrisentan Methyl Ester
    [catalogue_number] => PA 28 46540
    [category_ids] => ,80,84,78,
    [chemical_name] => 
    [weight] => 392.45
    [form] => C23H24N2O4
    [cas] => 1106685-61-3
    [pslug] => 1106685-61-3-ambrisentan-methyl-ester-pa2846540
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PA 28 46540

Ambrisentan Methyl Ester


  • Catalogue No.:PA 28 46540

  • CAS :

    1106685-61-3

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.45

stdClass Object
(
    [pname] => (R)-Ambrisentan
    [catalogue_number] => PA 28 46560
    [category_ids] => ,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 378.16
    [form] => C22H22N2O4
    [cas] => 1007358-76-0
    [pslug] => 1007358-76-0-r-ambrisentan-pa2846560
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PA 28 46560

(R)-Ambrisentan


  • Catalogue No.:PA 28 46560

  • CAS :

    1007358-76-0

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.16

stdClass Object
(
    [pname] => rac Ambrisentan-d3
    [catalogue_number] => PA STI 005030
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 381.44
    [form] => C22H19D3N2O4
    [cas] => 1189479-60-4
    [pslug] => 1189479-60-4-rac-ambrisentan-d3-pasti005030
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PA STI 005030

rac Ambrisentan-d3


  • Catalogue No.:PA STI 005030

  • CAS :

    1189479-60-4

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.44

stdClass Object
(
    [pname] => rac Ambrisentan-d3 Methyl Ester
    [catalogue_number] => PA STI 005040
    [category_ids] => ,80,78,70,82,98,
    [chemical_name] => 
    [weight] => 395.47
    [form] => C23H21D3N2O4
    [cas] => 1329837-75-3
    [pslug] => 1329837-75-3-rac-ambrisentan-d3-methyl-ester-pasti005040
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PA STI 005040

rac Ambrisentan-d3 Methyl Ester


  • Catalogue No.:PA STI 005040

  • CAS :

    1329837-75-3

  • Molecular Formula : C23H21D3N2O4

  • Molecular Weight : 395.47

stdClass Object
(
    [pname] => 4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5
    [catalogue_number] => PA STI 033300
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 415.45
    [form] => C22H17D5N2O6
    [cas] => 1346597-40-7
    [pslug] => 1346597-40-7-4-6-dimethoxy-beta-methyl-3-phenoxy-ambrisentan-d5-pasti033300
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PA STI 033300

4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5


  • Catalogue No.:PA STI 033300

  • CAS :

    1346597-40-7

  • Molecular Formula : C22H17D5N2O6

  • Molecular Weight : 415.45

stdClass Object
(
    [pname] => 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester
    [catalogue_number] => PA STI 049730
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 289.34
    [form] => C17H15D3O4
    [cas] => 1046116-52-2
    [pslug] => 1046116-52-2-2-hydroxy-3-methoxy-3-3-diphenylpropanoic-acid-d3-methyl-ester-pasti049730
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PA STI 049730

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester


  • Catalogue No.:PA STI 049730

  • CAS :

    1046116-52-2

  • Molecular Formula : C17H15D3O4

  • Molecular Weight : 289.34

stdClass Object
(
    [pname] => rac 4-Hydroxymethyl Ambrisentan-d3
    [catalogue_number] => PA STI 050030
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 397.44
    [form] => C22H19D3N2O5
    [cas] =>  1287096-42-7
    [pslug] => 1287096-42-7-rac-4-hydroxymethyl-ambrisentan-d3-pasti050030
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PA STI 050030

rac 4-Hydroxymethyl Ambrisentan-d3


  • Catalogue No.:PA STI 050030

  • CAS :

    1287096-42-7

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.44

stdClass Object
(
    [pname] => rac Ambrisentan Methyl Ester
    [catalogue_number] => PA 28 46600
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 392.45
    [form] => C23H24N2O4
    [cas] => 1240470-84-1
    [pslug] => 1240470-84-1-rac-ambrisentan-methyl-ester-pa2846600
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PA 28 46600

rac Ambrisentan Methyl Ester


  • Catalogue No.:PA 28 46600

  • CAS :

    1240470-84-1

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.45

stdClass Object
(
    [pname] => Ambrisentan Acyl β-D-Glucuronide
    [catalogue_number] => PA 28 46610
    [category_ids] => ,80,95,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 554.55
    [form] => C28H30N20O10
    [cas] => 1106685-58-8
    [pslug] => 1106685-58-8-ambrisentan-acyl-beta-d-glucuronide-pa2846610
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PA 28 46610

Ambrisentan Acyl β-D-Glucuronide


  • Catalogue No.:PA 28 46610

  • CAS :

    1106685-58-8

  • Molecular Formula : C28H30N20O10

  • Molecular Weight : 554.55

stdClass Object
(
    [pname] => Rac O-Demethyl Ambrisentan
    [catalogue_number] => PA 28 0461010
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 364.4
    [form] => C21H20N2O4
    [cas] => NA
    [pslug] => rac-o-demethyl-ambrisentan-pa280461010
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PA 28 0461010

Rac O-Demethyl Ambrisentan


  • Catalogue No.:PA 28 0461010

  • CAS :

    NA

  • Molecular Formula : C21H20N2O4

  • Molecular Weight : 364.4