Bendamustine Hydrochloride-Impurities | Pharmaffiliates

bendamustine hydrochloride

An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Hydroxy Bendamustine
    [catalogue_number] => PA 02 07590
    [category_ids] => ,70,71,80,
    [chemical_name] => 
    [weight] => 339.82
    [form] => C16H22ClN3O3
    [cas] => 109882-27-1
    [pslug] => 109882-27-1-hydroxy-bendamustine-pa0207590
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PA 02 07590

Hydroxy Bendamustine


  • Catalogue No.:PA 02 07590

  • CAS :

    109882-27-1

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

stdClass Object
(
    [pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07610
    [category_ids] => ,70,71,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 353.87
    [form] => C16H20ClN3O2S
    [cas] => 191939-34-1
    [pslug] => 191939-34-1-4-6-2-chloroethyl-3-methyl-3-6-7-8-tetrahydroimidazo-4-5-5-6-benzo-1-2-b-1-4-thiazin-2-yl-butanoic-acid-pa0207610
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PA 02 07610

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07610

  • CAS :

    191939-34-1

  • Molecular Formula : C16H20ClN3O2S

  • Molecular Weight : 353.87

stdClass Object
(
    [pname] => Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate
    [catalogue_number] => PA 02 07620
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 305.33
    [form] => C15H19N3O4
    [cas] => 1374784-01-6
    [pslug] => 1374784-01-6-isopropyl-4-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-butanoate-pa0207620
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PA 02 07620

Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate


  • Catalogue No.:PA 02 07620

  • CAS :

    1374784-01-6

  • Molecular Formula : C15H19N3O4

  • Molecular Weight : 305.33

stdClass Object
(
    [pname] => 1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane
    [catalogue_number] => PA 02 07630
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 394.38
    [form] => C19H18N6O4
    [cas] => 914626-65-6
    [pslug] => 914626-65-6-1-3-bis-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-propane-pa0207630
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PA 02 07630

1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane


  • Catalogue No.:PA 02 07630

  • CAS :

    914626-65-6

  • Molecular Formula : C19H18N6O4

  • Molecular Weight : 394.38

stdClass Object
(
    [pname] => N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide
    [catalogue_number] => PA 02 07640
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 430.41
    [form] => C19H22N6O6
    [cas] => NA
    [pslug] => n1-n5-bis-2-methylamino-5-nitrophenyl-glutaramide-pa0207640
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PA 02 07640

N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide


  • Catalogue No.:PA 02 07640

  • CAS :

    NA

  • Molecular Formula : C19H22N6O6

  • Molecular Weight : 430.41

stdClass Object
(
    [pname] => 2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)
    [catalogue_number] => PA 02 07650
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 334.42
    [form] => C19H22N6
    [cas] => 847588-86-7
    [pslug] => 847588-86-7-2-2-propane-1-3-diyl-bis-1-methyl-1h-benzo-d-imidazol-5-amine-pa0207650
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PA 02 07650

2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)


  • Catalogue No.:PA 02 07650

  • CAS :

    847588-86-7

  • Molecular Formula : C19H22N6

  • Molecular Weight : 334.42

stdClass Object
(
    [pname] => 2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07660
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 432.34
    [form] => C19H27Cl2N3O4
    [cas] => NA
    [pslug] => 2-3-dihydroxypropyl-4-5-bis-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207660
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PA 02 07660

2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07660

  • CAS :

    NA

  • Molecular Formula : C19H27Cl2N3O4

  • Molecular Weight : 432.34

stdClass Object
(
    [pname] => 4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07670
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 381.85
    [form] => C18H24ClN3O4
    [cas] => NA
    [pslug] => 4-5-2-acetoxyethyl-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa0207670
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PA 02 07670

4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid


  • Catalogue No.:PA 02 07670

  • CAS :

    NA

  • Molecular Formula : C18H24ClN3O4

  • Molecular Weight : 381.85

stdClass Object
(
    [pname] => Deschloroethyl Bendamustine
    [catalogue_number] => PA 02 07680
    [category_ids] => ,70,78,80,82,98,
    [chemical_name] => 
    [weight] => 295.76
    [form] => C14H18ClN3O2
    [cas] => 1219709-86-0
    [pslug] => 1219709-86-0-deschloroethyl-bendamustine-pa0207680
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PA 02 07680

Deschloroethyl Bendamustine


  • Catalogue No.:PA 02 07680

  • CAS :

    1219709-86-0

  • Molecular Formula : C14H18ClN3O2

  • Molecular Weight : 295.76

stdClass Object
(
    [pname] => Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07690
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 335.4
    [form] => C17H25N3O4
    [cas] => 109882-31-7
    [pslug] => 109882-31-7-methyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207690
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PA 02 07690

Methyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07690

  • CAS :

    109882-31-7

  • Molecular Formula : C17H25N3O4

  • Molecular Weight : 335.4

stdClass Object
(
    [pname] => 2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07700
    [category_ids] => ,80,98,78,70,82,
    [chemical_name] => 
    [weight] => 666.81
    [form] => C35H50N6O7
    [cas] => NA
    [pslug] => 2-2-hydroxyethyl-2-4-isopropoxy-4-oxobutyl-1-methyl-1h-benzo-d-imidazol-5-yl-amino-ethyl-4-5-bis-2-hydroxyethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207700
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PA 02 07700

2-((2-Hydroxyethyl)(2-(4-isopropoxy-4-oxobutyl)-1-methyl-1H-benzo[d]imidazol-5-yl)amino)ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate


  • Catalogue No.:PA 02 07700

  • CAS :

    NA

  • Molecular Formula : C35H50N6O7

  • Molecular Weight : 666.81

stdClass Object
(
    [pname] => N-Methyl-2-amino-4-nitroaniline
    [catalogue_number] => PA 02 07770
    [category_ids] => ,79,80,
    [chemical_name] => 
    [weight] => 167.17
    [form] => C7H9N3O2
    [cas] => 41939-61-1
    [pslug] => 41939-61-1-n-methyl-2-amino-4-nitroaniline-pa0207770
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PA 02 07770

N-Methyl-2-amino-4-nitroaniline


  • Catalogue No.:PA 02 07770

  • CAS :

    41939-61-1

  • Molecular Formula : C7H9N3O2

  • Molecular Weight : 167.17

stdClass Object
(
    [pname] => Bendamustine Dihydroxy
    [catalogue_number] => PA 02 07810
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 357.84
    [form] => C16H24ClN3O4
    [cas] => 109882-29-3
    [pslug] => 109882-29-3-bendamustine-dihydroxy-pa0207810
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PA 02 07810

Bendamustine Dihydroxy


  • Catalogue No.:PA 02 07810

  • CAS :

    109882-29-3

  • Molecular Formula : C16H24ClN3O4

  • Molecular Weight : 357.84

stdClass Object
(
    [pname] => Bendamustine Ether  Hydrochloride Impurity
    [catalogue_number] => PA 02 07820
    [category_ids] => ,82,80,78,70,
    [chemical_name] => 
    [weight] => 339.82
    [form] => C16H22ClN3O3
    [cas] => 2173004-95-8
    [pslug] => 2173004-95-8-bendamustine-ether-hydrochloride-impurity-pa0207820
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PA 02 07820

Bendamustine Ether Hydrochloride Impurity


  • Catalogue No.:PA 02 07820

  • CAS :

    2173004-95-8

  • Molecular Formula : C16H22ClN3O3

  • Molecular Weight : 339.82

stdClass Object
(
    [pname] => Bendamustine Mannitol Ester
    [catalogue_number] => PA 02 07840
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 522.42
    [form] => C22H33Cl2N3O7
    [cas] => 1869075-89-7
    [pslug] => 1869075-89-7-bendamustine-mannitol-ester-pa0207840
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PA 02 07840

Bendamustine Mannitol Ester


  • Catalogue No.:PA 02 07840

  • CAS :

    1869075-89-7

  • Molecular Formula : C22H33Cl2N3O7

  • Molecular Weight : 522.42

stdClass Object
(
    [pname] => 5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid
    [catalogue_number] => PA 02 07850
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 374.26
    [form] => C16H21Cl2N3O3
    [cas] => 1138238-08-0
    [pslug] => 1138238-08-0-5-bis-2-chloroethyl-amino-gamma-hydroxy-1-methyl-1h-benzimidazole-2-butanoic-acid-pa0207850
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PA 02 07850

5-[Bis(2-chloroethyl)amino]-γ-hydroxy-1-methyl-1H-benzimidazole-2-butanoic Acid


  • Catalogue No.:PA 02 07850

  • CAS :

    1138238-08-0

  • Molecular Formula : C16H21Cl2N3O3

  • Molecular Weight : 374.26

stdClass Object
(
    [pname] => N-Desmethylbendamustine
    [catalogue_number] => PA 02 07860
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 344.24
    [form] => C15H19Cl2N3O2
    [cas] => 41515-13-3
    [pslug] => 41515-13-3-n-desmethylbendamustine-pa0207860
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PA 02 07860

N-Desmethylbendamustine


  • Catalogue No.:PA 02 07860

  • CAS :

    41515-13-3

  • Molecular Formula : C15H19Cl2N3O2

  • Molecular Weight : 344.24

stdClass Object
(
    [pname] => [1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester
    [catalogue_number] => PA 02 07830
    [category_ids] => ,70,78,80,82,
    [chemical_name] => 
    [weight] => 349.43
    [form] => C18H27N3O4
    [cas] => 3543-74-6
    [pslug] => 3543-74-6-1-methyl-5-bis-2-hydroxyethyl-aminobenzimidazolyl-2-butanoic-acid-ethyl-ester-pa0207830
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PA 02 07830

[1-Methyl-5-bis(2'-hydroxyethyl)aminobenzimidazolyl-2]butanoic Acid Ethyl Ester


  • Catalogue No.:PA 02 07830

  • CAS :

    3543-74-6

  • Molecular Formula : C18H27N3O4

  • Molecular Weight : 349.43