Donepezil-impurities | Pharmaffiliates

donepezil

A reversible acetylcholinesterase inhibitor, Donepezil is used for the treatment of of Alzheimer's disease. It is a medication used in palliative treatment. It works by inhibiting the hydrolysis of acetylcholine.. Reference standards of Donepezil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Donepezil - Impurity B
    [catalogue_number] => PA 04 40020
    [category_ids] => ,80,70,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 2107-69-9
    [pslug] => 2107-69-9-donepezil-impurity-b-pa0440020
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PA 04 40020

Donepezil - Impurity B


  • Catalogue No.:PA 04 40020

  • CAS :

    2107-69-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => Deoxy Donepezil Hydrochloride
    [catalogue_number] => PA 04 40560
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 401.97
    [form] => C24H32ClNO2
    [cas] => 1034439-57-0
    [pslug] => 1034439-57-0-deoxy-donepezil-hydrochloride-pa0440560
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PA 04 40560

Deoxy Donepezil Hydrochloride


  • Catalogue No.:PA 04 40560

  • CAS :

    1034439-57-0

  • Molecular Formula : C24H32ClNO2

  • Molecular Weight : 401.97

stdClass Object
(
    [pname] => Donepezil Pyridine N-Oxide
    [catalogue_number] => PA 04 40620
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 299.32
    [form] => C17H17NO4
    [cas] => 896134-07-9
    [pslug] => 896134-07-9-donepezil-pyridine-n-oxide-pa0440620
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PA 04 40620

Donepezil Pyridine N-Oxide


  • Catalogue No.:PA 04 40620

  • CAS :

    896134-07-9

  • Molecular Formula : C17H17NO4

  • Molecular Weight : 299.32

stdClass Object
(
    [pname] => 4,5-Dimethoxy-1-indanone
    [catalogue_number] => PA 04 40630
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 6342-80-9
    [pslug] => 6342-80-9-4-5-dimethoxy-1-indanone-pa0440630
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PA 04 40630

4,5-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40630

  • CAS :

    6342-80-9

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 4,6-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40640
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 13336-32-8
    [pslug] => 13336-32-8-4-6-dimethoxy-2-3-dihydroinden-1-one-pa0440640
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PA 04 40640

4,6-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40640

  • CAS :

    13336-32-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 4,7-Dimethoxy-1-indanone
    [catalogue_number] => PA 04 40650
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 52428-09-8
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PA 04 40650

4,7-Dimethoxy-1-indanone


  • Catalogue No.:PA 04 40650

  • CAS :

    52428-09-8

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
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    [pname] => 5,7-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40660
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 880-87-5
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PA 04 40660

5,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40660

  • CAS :

    880-87-5

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
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    [pname] => 6,7-Dimethoxy-2,3-dihydroinden-1-one
    [catalogue_number] => PA 04 40670
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 57441-74-4
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PA 04 40670

6,7-Dimethoxy-2,3-dihydroinden-1-one


  • Catalogue No.:PA 04 40670

  • CAS :

    57441-74-4

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
    [catalogue_number] => PA 04 40680
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 379.49
    [form] => C24H29NO3
    [cas] => 736104-42-0
    [pslug] => 736104-42-0-1-benzyl-4-6-7-dimethoxy-1-oxoindan-2-yl-methyl-piperidine-pa0440680
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PA 04 40680

1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine


  • Catalogue No.:PA 04 40680

  • CAS :

    736104-42-0

  • Molecular Formula : C24H29NO3

  • Molecular Weight : 379.49

stdClass Object
(
    [pname] => Donepezil Dehydro Impurity (E/Z mixture)
    [catalogue_number] => PA 04 40690
    [category_ids] => ,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 377.48
    [form] => C24H27NO3
    [cas] => 120014-07-5
    [pslug] => 120014-07-5-donepezil-dehydro-impurity-e-z-mixture-pa0440690
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PA 04 40690

Donepezil Dehydro Impurity (E/Z mixture)


  • Catalogue No.:PA 04 40690

  • CAS :

    120014-07-5

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

stdClass Object
(
    [pname] => Donepezil Hydrochloride Monohydrate - Impurity G
    [catalogue_number] => PA 04 40700
    [category_ids] => ,70,71,78,80,82,
    [chemical_name] => 
    [weight] => 377.48
    [form] => C24H27NO3
    [cas] => 2452407-72-4
    [pslug] => 2452407-72-4-donepezil-hydrochloride-monohydrate-impurity-g-pa0440700
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PA 04 40700

Donepezil Hydrochloride Monohydrate - Impurity G


  • Catalogue No.:PA 04 40700

  • CAS :

    2452407-72-4

  • Molecular Formula : C24H27NO3

  • Molecular Weight : 377.48

stdClass Object
(
    [pname] => 5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one
    [catalogue_number] => PA 04 40720
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 287.35
    [form] => C17H21NO3
    [cas] => 149874-91-9
    [pslug] => 149874-91-9-5-6-dimethoxy-2-4-piperidinyl-methyleneindan-1-one-pa0440720
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PA 04 40720

5,6-Dimethoxy-2-(4-piperidinyl)methyleneindan-1-one


  • Catalogue No.:PA 04 40720

  • CAS :

    149874-91-9

  • Molecular Formula : C17H21NO3

  • Molecular Weight : 287.35

stdClass Object
(
    [pname] => 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3
    [catalogue_number] => PA STI 011340
    [category_ids] => ,80,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 380.45
    [form] => C2113C3H27NO3
    [cas] => 1185239-87-5
    [pslug] => 1185239-87-5-1-benzyl-4-5-6-dimethoxy-1-oxoindan-2-ylidene-methyl-piperidine-13c3-pasti011340
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PA STI 011340

1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine-13C3


  • Catalogue No.:PA STI 011340

  • CAS :

    1185239-87-5

  • Molecular Formula : C2113C3H27NO3

  • Molecular Weight : 380.45

stdClass Object
(
    [pname] => 4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide
    [catalogue_number] => PA STI 032760
    [category_ids] => ,70,71,78,80,81,82,98,
    [chemical_name] => 
    [weight] => 564.61
    [form] => C31H22D14BrNO3
    [cas] => NA
    [pslug] => 4-2-3-dihydro-5-6-dimethoxy-1-oxo-1h-inden-2-yl-methyl-1-1-bis-phenylmethyl-piperidinium-d14-bromide-pasti032760
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PA STI 032760

4-[(2,3-Dihydro-5,6-dimethoxy-1-oxo-1H-inden-2-yl)methyl]-1,1-bis(phenylmethyl)piperidinium-d14 Bromide


  • Catalogue No.:PA STI 032760

  • CAS :

    NA

  • Molecular Formula : C31H22D14BrNO3

  • Molecular Weight : 564.61

stdClass Object
(
    [pname] => 5,6-Dimethoxy-1-indanone-13C3
    [catalogue_number] => PA STI 033470
    [category_ids] => ,80,70,98,
    [chemical_name] => 
    [weight] => 195.19
    [form] => C813C3H12O3
    [cas] => 1185155-55-8
    [pslug] => 1185155-55-8-5-6-dimethoxy-1-indanone-13c3-pasti033470
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PA STI 033470

5,6-Dimethoxy-1-indanone-13C3


  • Catalogue No.:PA STI 033470

  • CAS :

    1185155-55-8

  • Molecular Formula : C813C3H12O3

  • Molecular Weight : 195.19

stdClass Object
(
    [pname] => Donepezil-d7 Hydrochloride
    [catalogue_number] => PA STI 036190
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 423.00
    [form] => C24H23D7ClNO3
    [cas] =>   1261394-20-0
    [pslug] => 1261394-20-0-donepezil-d7-hydrochloride-pasti036190
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PA STI 036190

Donepezil-d7 Hydrochloride


  • Catalogue No.:PA STI 036190

  • CAS :

    1261394-20-0

  • Molecular Formula : C24H23D7ClNO3

  • Molecular Weight : 423.00

stdClass Object
(
    [pname] => Donepezil-13C3 Hydrochloride
    [catalogue_number] => PA STI 036200
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 418.93
    [form] => C2113C3H30ClNO3
    [cas] => 1246814-90-3
    [pslug] => 1246814-90-3-donepezil-13c3-hydrochloride-pasti036200
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PA STI 036200

Donepezil-13C3 Hydrochloride


  • Catalogue No.:PA STI 036200

  • CAS :

    1246814-90-3

  • Molecular Formula : C2113C3H30ClNO3

  • Molecular Weight : 418.93

stdClass Object
(
    [pname] => Donepezil - Impurity E (Bromide Salt)
    [catalogue_number] => PA 04 40050
    [category_ids] => ,70,71,75,78,80,82,
    [chemical_name] => 
    [weight] => 454.36
    [form] => C24H24BrNO3
    [cas] => 231283-82-2
    [pslug] => 231283-82-2-donepezil-impurity-e-bromide-salt-pa0440050
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PA 04 40050

Donepezil - Impurity E (Bromide Salt)


  • Catalogue No.:PA 04 40050

  • CAS :

    231283-82-2

  • Molecular Formula : C24H24BrNO3

  • Molecular Weight : 454.36

stdClass Object
(
    [pname] => 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
    [catalogue_number] => PA 04 40740
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 281.31
    [form] => C17H15NO3
    [cas] => 4803-74-1
    [pslug] => 4803-74-1-5-6-dimethoxy-2-4-pyridylmethylene-1-indanone-pa0440740
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PA 04 40740

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone


  • Catalogue No.:PA 04 40740

  • CAS :

    4803-74-1

  • Molecular Formula : C17H15NO3

  • Molecular Weight : 281.31

stdClass Object
(
    [pname] => 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one
    [catalogue_number] => PA 04 40750
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 297.31
    [form] => C17H15NO4
    [cas] => 896134-06-8
    [pslug] => 896134-06-8-2-3-dihydro-5-6-dimethoxy-2-1-oxido-4-pyridinyl-methylene-1h-inden-1-one-pa0440750
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PA 04 40750

2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one


  • Catalogue No.:PA 04 40750

  • CAS :

    896134-06-8

  • Molecular Formula : C17H15NO4

  • Molecular Weight : 297.31

stdClass Object
(
    [pname] => Donepezil Keto Acid Sodium Salt
    [catalogue_number] => PA 04 40770
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 433.48
    [form] => C24H28NNaO5
    [cas] => NA
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PA 04 40770

Donepezil Keto Acid Sodium Salt


  • Catalogue No.:PA 04 40770

  • CAS :

    NA

  • Molecular Formula : C24H28NNaO5

  • Molecular Weight : 433.48

stdClass Object
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    [pname] => Donepezil Open-Ring Hydroxy Acid
    [catalogue_number] => PA 04 40780
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 413.51
    [form] => C24H31NO5
    [cas] => NA
    [pslug] => donepezil-open-ring-hydroxy-acid-pa0440780
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PA 04 40780

Donepezil Open-Ring Hydroxy Acid


  • Catalogue No.:PA 04 40780

  • CAS :

    NA

  • Molecular Formula : C24H31NO5

  • Molecular Weight : 413.51

stdClass Object
(
    [pname] => 2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
    [catalogue_number] => PA 04 40790
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => NA
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PA 04 40790

2-((1-Benzyl-2-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40790

  • CAS :

    NA

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

stdClass Object
(
    [pname] => 2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
    [catalogue_number] => PA 04 40800
    [category_ids] => ,80,71,70,79,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => 2514735-34-1
    [pslug] => 2514735-34-1-2-1-benzyl-3-hydroxypiperidin-4-yl-methyl-5-6-dimethoxy-2-3-dihydro-1h-inden-1-one-pa0440800
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PA 04 40800

2-((1-Benzyl-3-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one


  • Catalogue No.:PA 04 40800

  • CAS :

    2514735-34-1

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5

stdClass Object
(
    [pname] => Donepezil Hydrochloride Monohydrate - Impurity C
    [catalogue_number] => PA 04 40030
    [category_ids] => ,70,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 395.5
    [form] => C24H29NO4
    [cas] => 2452407-76-8
    [pslug] => 2452407-76-8-donepezil-hydrochloride-monohydrate-impurity-c-pa0440030
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PA 04 40030

Donepezil Hydrochloride Monohydrate - Impurity C


  • Catalogue No.:PA 04 40030

  • CAS :

    2452407-76-8

  • Molecular Formula : C24H29NO4

  • Molecular Weight : 395.5