Osimertinib-impurities | Pharmaffiliates

osimertinib

Osimertinib is used to treat locally advanced or metastatic non-small-cell lung cancer. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor.Reference standards of Osimertinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Osimertinib - API Standards 
    [catalogue_number] => PA 15 51000
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 499.61
    [form] => C28H33N7O2
    [cas] => 1421373-65-0
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PA 15 51000

Osimertinib - API Standards


  • Catalogue No.:PA 15 51000

  • CAS :

    1421373-65-0

  • Molecular Formula : C28H33N7O2

  • Molecular Weight : 499.61

stdClass Object
(
    [pname] => 3,3'-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)
    [catalogue_number] => PA 15 51510
    [category_ids] => ,70,71,75,78,80,82,
    [chemical_name] => 
    [weight] => 338.41
    [form] => C22H18N4
    [cas] => 2364486-24-6
    [pslug] => 2364486-24-6-3-3-pyrimidine-2-4-diyl-bis-1-methyl-1h-indole-pa1551510
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PA 15 51510

3,3'-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)


  • Catalogue No.:PA 15 51510

  • CAS :

    2364486-24-6

  • Molecular Formula : C22H18N4

  • Molecular Weight : 338.41

stdClass Object
(
    [pname] => 3-(4-Chloropyrimidin-2-yl)-1-methyl-1H-indole
    [catalogue_number] => PA 15 51520
    [category_ids] => ,70,71,75,78,80,82,
    [chemical_name] => 
    [weight] => 243.69
    [form] => C13H10ClN3
    [cas] => 2364486-23-5
    [pslug] => 2364486-23-5-3-4-chloropyrimidin-2-yl-1-methyl-1h-indole-pa1551520
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PA 15 51520

3-(4-Chloropyrimidin-2-yl)-1-methyl-1H-indole


  • Catalogue No.:PA 15 51520

  • CAS :

    2364486-23-5

  • Molecular Formula : C13H10ClN3

  • Molecular Weight : 243.69

stdClass Object
(
    [pname] => 4-Fluoro-2-methoxy-3-nitroaniline
    [catalogue_number] => PA 15 51530
    [category_ids] => ,70,75,78,80,82,89,
    [chemical_name] => 
    [weight] => 186.14
    [form] => C7H7FN2O3
    [cas] => 2090542-75-7
    [pslug] => 2090542-75-7-4-fluoro-2-methoxy-3-nitroaniline-pa1551530
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PA 15 51530

4-Fluoro-2-methoxy-3-nitroaniline


  • Catalogue No.:PA 15 51530

  • CAS :

    2090542-75-7

  • Molecular Formula : C7H7FN2O3

  • Molecular Weight : 186.14

stdClass Object
(
    [pname] => 2,4-Difluoronitrobenzene
    [catalogue_number] => PA 15 51540
    [category_ids] => ,80,84,75,89,
    [chemical_name] => 
    [weight] => 159.09
    [form] => C6H3F2NO2
    [cas] => 446-35-5
    [pslug] => 446-35-5-2-4-difluoronitrobenzene-pa1551540
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PA 15 51540

2,4-Difluoronitrobenzene


  • Catalogue No.:PA 15 51540

  • CAS :

    446-35-5

  • Molecular Formula : C6H3F2NO2

  • Molecular Weight : 159.09

stdClass Object
(
    [pname] => 2-(tert-Butoxy)-4-fluoro-5-nitroaniline
    [catalogue_number] => PA 15 51560
    [category_ids] => ,79,75,80,89,
    [chemical_name] => 
    [weight] => 228.22
    [form] => C10H13FN2O3
    [cas] => NA
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PA 15 51560

2-(tert-Butoxy)-4-fluoro-5-nitroaniline


  • Catalogue No.:PA 15 51560

  • CAS :

    NA

  • Molecular Formula : C10H13FN2O3

  • Molecular Weight : 228.22

stdClass Object
(
    [pname] => 4-Fluoro-6-methoxy-2,3-dinitroaniline
    [catalogue_number] => PA 15 51570
    [category_ids] => ,79,75,80,89,
    [chemical_name] => 
    [weight] => 231.14
    [form] => C7H6FN3O5
    [cas] => NA
    [pslug] => 4-fluoro-6-methoxy-2-3-dinitroaniline-pa1551570
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PA 15 51570

4-Fluoro-6-methoxy-2,3-dinitroaniline


  • Catalogue No.:PA 15 51570

  • CAS :

    NA

  • Molecular Formula : C7H6FN3O5

  • Molecular Weight : 231.14

stdClass Object
(
    [pname] => Osimertinib N-Oxide
    [catalogue_number] => PA 15 0511000
    [category_ids] => 82,80,78,75,71,70
    [chemical_name] => 
    [weight] => 515.62
    [form] => C28H33N7O3
    [cas] => 2411395-22-5
    [pslug] => 2411395-22-5-osimertinib-n-oxide-pa150511000
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PA 15 0511000

Osimertinib N-Oxide


  • Catalogue No.:PA 15 0511000

  • CAS :

    2411395-22-5

  • Molecular Formula : C28H33N7O3

  • Molecular Weight : 515.62

stdClass Object
(
    [pname] => Osimertinib N-Methylacrylamide Impurity
    [catalogue_number] => PA 15 0511027
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 539.64
    [form] => C30H33N7O3
    [cas] => 2850389-35-2
    [pslug] => 2850389-35-2-osimertinib-n-methylacrylamide-impurity-pa150511027
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PA 15 0511027

Osimertinib N-Methylacrylamide Impurity


  • Catalogue No.:PA 15 0511027

  • CAS :

    2850389-35-2

  • Molecular Formula : C30H33N7O3

  • Molecular Weight : 539.64

stdClass Object
(
    [pname] => 1-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)azetidin-2-one
    [catalogue_number] => PA 15 0511028
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 499.62
    [form] => C28H33N7O2
    [cas] => NA
    [pslug] => 1-2-2-dimethylamino-ethyl-methyl-amino-4-methoxy-5-4-1-methyl-1h-indol-3-yl-pyrimidin-2-yl-amino-phenyl-azetidin-2-one-pa150511028
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PA 15 0511028

1-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)azetidin-2-one


  • Catalogue No.:PA 15 0511028

  • CAS :

    NA

  • Molecular Formula : C28H33N7O2

  • Molecular Weight : 499.62

stdClass Object
(
    [pname] => N-(4-Fluoro-2-methoxyphenyl)acetamide
    [catalogue_number] => PA 15 0511029
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 183.18
    [form] => C9H10FNO2
    [cas] => 582-11-6
    [pslug] => 582-11-6-n-4-fluoro-2-methoxyphenyl-acetamide-pa150511029
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PA 15 0511029

N-(4-Fluoro-2-methoxyphenyl)acetamide


  • Catalogue No.:PA 15 0511029

  • CAS :

    582-11-6

  • Molecular Formula : C9H10FNO2

  • Molecular Weight : 183.18

stdClass Object
(
    [pname] => 1-Fluoro-5-methoxy-2,4-dinitrobenzene
    [catalogue_number] => PA 15 0511030
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 216.12
    [form] => C7H5FN2O5
    [cas] => 394-18-3
    [pslug] => 394-18-3-1-fluoro-5-methoxy-2-4-dinitrobenzene-pa150511030
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PA 15 0511030

1-Fluoro-5-methoxy-2,4-dinitrobenzene


  • Catalogue No.:PA 15 0511030

  • CAS :

    394-18-3

  • Molecular Formula : C7H5FN2O5

  • Molecular Weight : 216.12

stdClass Object
(
    [pname] => N-(4-Fluoro-2-methoxy-5-nitrophenyl)acetamide
    [catalogue_number] => PA 15 0511031
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 228.18
    [form] => C9H9FN2O4
    [cas] => 1823445-36-8
    [pslug] => 1823445-36-8-n-4-fluoro-2-methoxy-5-nitrophenyl-acetamide-pa150511031
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PA 15 0511031

N-(4-Fluoro-2-methoxy-5-nitrophenyl)acetamide


  • Catalogue No.:PA 15 0511031

  • CAS :

    1823445-36-8

  • Molecular Formula : C9H9FN2O4

  • Molecular Weight : 228.18