afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif. Reference standards of Afatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Afatinib - API Standards [catalogue_number] => PA 28 02000 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 485.94 [form] => C24H25ClFN5O3 [cas] => 850140-72-6 [pslug] => 850140-72-6-afatinib-api-pa2802000 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 02000
CAS :
Molecular Formula : C24H25ClFN5O3
Molecular Weight : 485.94
stdClass Object ( [pname] => (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 28 02630 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 485.94 [form] => C24H25ClFN5O3 [cas] => 1680184-59-1 [pslug] => 1680184-59-1-s-z-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 02630
stdClass Object ( [pname] => (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine [catalogue_number] => PA 28 02650 [category_ids] => ,79,80,69,71,78,70,82, [chemical_name] => [weight] => 404.78 [form] => C18H14ClFN4O4 [cas] => 314771-88-5 [pslug] => 314771-88-5-s-n-3-chloro-4-fluorophenyl-6-nitro-7-tetrahydrofuran-3-yloxy-quinazolin-4-amine-pa2802650 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 02650
Molecular Formula : C18H14ClFN4O4
Molecular Weight : 404.78
stdClass Object ( [pname] => (S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 28 02660 [category_ids] => ,79,80,69,71,78,70,82, [chemical_name] => [weight] => 469.48 [form] => C24H25F2N5O3 [cas] => 2223677-62-9 [pslug] => 2223677-62-9-s-e-n-4-3-4-difluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802660 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 02660
Molecular Formula : C24H25F2N5O3
Molecular Weight : 469.48
stdClass Object ( [pname] => (S,E)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide [catalogue_number] => PA 28 02670 [category_ids] => ,79,80,69,71,78,70,82, [chemical_name] => [weight] => 442.87 [form] => C22H20ClFN4O3 [cas] => NA [pslug] => s-e-n-4-4-chloro-3-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-but-2-enamide-pa2802670 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 02670
Molecular Formula : C22H20ClFN4O3
Molecular Weight : 442.87
stdClass Object ( [pname] => N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine [catalogue_number] => PA 28 0021016 [category_ids] => ,69,71,78,70,82, [chemical_name] => [weight] => 320.23 [form] => C14H7F3N4O2 [cas] => 2226537-61-5 [pslug] => 2226537-61-5-n-3-4-difluorophenyl-7-fluoro-6-nitroquinazolin-4-amine-pa280021016 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021016
Molecular Formula : C14H7F3N4O2
Molecular Weight : 320.23
stdClass Object ( [pname] => 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol [catalogue_number] => PA 28 0021017 [category_ids] => ,69,71,78,70,82, [chemical_name] => [weight] => 334.69 [form] => C14H8ClFN4O3 [cas] => 1449430-45-8 [pslug] => 1449430-45-8-4-3-chloro-4-fluorophenyl-amino-6-nitroquinazolin-7-ol-pa280021017 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021017
Molecular Formula : C14H8ClFN4O3
Molecular Weight : 334.69
stdClass Object ( [pname] => (S)-N4-(3,4-Dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine [catalogue_number] => PA 28 0021018 [category_ids] => ,69,71,78,70,82, [chemical_name] => [weight] => 391.25 [form] => C18H16Cl2N4O2 [cas] => 2044709-79-5 [pslug] => 2044709-79-5-s-n4-3-4-dichlorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa280021018 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021018
Molecular Formula : C18H16Cl2N4O2
Molecular Weight : 391.25
stdClass Object ( [pname] => 3-(2-Pyridyl)-5,6-bis(4-sulfophenyl)-1,2,4-trazine Disodium Salt Hydrate [catalogue_number] => PA 28 0021020 [category_ids] => ,75,76,79,69,71,78,82, [chemical_name] => [weight] => 534.47 [form] => C20H16N4Na2O7S2 [cas] => 1083240-27-0 [pslug] => 1083240-27-0-3-2-pyridyl-5-6-bis-4-sulfophenyl-1-2-4-trazine-disodium-salt-hydrate-pa280021020 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021020
Molecular Formula : C20H16N4Na2O7S2
Molecular Weight : 534.47
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 28 0021022 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 415.85 [form] => C20H19ClFN5O2 [cas] => 2223677-61-8 [pslug] => 2223677-61-8-e-n-4-3-chloro-4-fluorophenyl-amino-7-hydroxyquinazolin-6-yl-4-dimethylamino-but-2-enamide-pa280021022 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021022
Molecular Formula : C20H19ClFN5O2
Molecular Weight : 415.85
stdClass Object ( [pname] => N1,N2-Bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide [catalogue_number] => PA 28 0021023 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 803.6 [form] => C38H30Cl2F2N8O6 [cas] => 2223677-65-2 [pslug] => 2223677-65-2-n1-n2-bis-4-3-chloro-4-fluorophenyl-amino-7-s-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-oxalamide-pa280021023 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021023
Molecular Formula : C38H30Cl2F2N8O6
Molecular Weight : 803.6
stdClass Object ( [pname] => (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide [catalogue_number] => PA 28 0021024 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 473.89 [form] => C22H21ClFN5O4 [cas] => 2223677-66-3 [pslug] => 2223677-66-3-s-n1-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-n2-n2-dimethyloxalamide-pa280021024 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021024
Molecular Formula : C22H21ClFN5O4
Molecular Weight : 473.89
stdClass Object ( [pname] => Afatinib N-Oxide [catalogue_number] => PA 28 0021025 [category_ids] => ,79,69,71,78,70,82, [chemical_name] => [weight] => 501.94 [form] => C24H25ClFN5O4 [cas] => 2413212-11-8 [pslug] => 2413212-11-8-afatinib-n-oxide-pa280021025 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0021025
Molecular Formula : C24H25ClFN5O4
Molecular Weight : 501.94
I accept terms and conditions
Message sent successfully!! We will get back to you shortly ....
