Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2.Reference standards of Rapamycin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Rapamycin Dialdehyde [catalogue_number] => PA 18 26510 [category_ids] => ,69,71,81,78,70,82, [chemical_name] => [weight] => 946.17 [form] => C51H79NO15 [cas] => 500733-49-3 [pslug] => 500733-49-3-rapamycin-dialdehyde-pa1826510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 26510
CAS :
Molecular Formula : C51H79NO15
Molecular Weight : 946.17
stdClass Object ( [pname] => 28-epi-Rapamycin [catalogue_number] => PA 18 26600 [category_ids] => ,69,71,81,78,70,82, [chemical_name] => [weight] => 914.17 [form] => C51H79NO13 [cas] => 253431-35-5 [pslug] => 253431-35-5-28-epi-rapamycin-pa1826600 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 26600
Molecular Formula : C51H79NO13
Molecular Weight : 914.17
stdClass Object ( [pname] => 29-Desmethoxy-rapamycin [catalogue_number] => PA 18 26610 [category_ids] => ,69,71,81,78,70,82, [chemical_name] => [weight] => 884.15 [form] => C50H77NO12 [cas] => NA [pslug] => 29-desmethoxy-rapamycin-pa1826610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 26610
Molecular Formula : C50H77NO12
Molecular Weight : 884.15
stdClass Object ( [pname] => 12-Ethyl Rapamycin [catalogue_number] => PA 18 26620 [category_ids] => ,69,71,81,78,70,82, [chemical_name] => [weight] => 928.2 [form] => C52H81NO13 [cas] => NA [pslug] => 12-ethyl-rapamycin-pa1826620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 26620
Molecular Formula : C52H81NO13
Molecular Weight : 928.2
stdClass Object ( [pname] => 33-Ethyl Rapamycin [catalogue_number] => PA 18 26630 [category_ids] => ,69,71,81,78,70,82, [chemical_name] => [weight] => 928.2 [form] => C52H81NO13 [cas] => NA [pslug] => 33-ethyl-rapamycin-pa1826630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 26630
stdClass Object ( [pname] => 42-O-tert-Butyldimethylsilyloxyethyl-d4 Rapamycin [catalogue_number] => PA STI 016250 [category_ids] => ,69,71,98, [chemical_name] => [weight] => 1076.51 [form] => C59H93D4NO14Si [cas] => 1356839-88-7 [pslug] => 1356839-88-7-42-o-tert-butyldimethylsilyloxyethyl-d4-rapamycin-pasti016250 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 016250
Molecular Formula : C59H93D4NO14Si
Molecular Weight : 1076.51
stdClass Object ( [pname] => (19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt [catalogue_number] => PA STI 047640 [category_ids] => ,92,69,74,98,76,75,78,70,82, [chemical_name] => [weight] => 984.23 [form] => C53H78D4NNaO14 [cas] => NA [pslug] => 19e-z-seco-4-o-2-hydroxy-ethyl-d4-rapamycin-sodium-salt-pasti047640 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 047640
Molecular Formula : C53H78D4NNaO14
Molecular Weight : 984.23
stdClass Object ( [pname] => (9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13S,14R,15E)-14-hydroxy-2,13-dimethoxy-3,9,11,15-tetramethyl-12,17-dioxooctadeca-3,5,7,15-tetraen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione [catalogue_number] => PA 18 0261012 [category_ids] => ,82,81,78,71,70,69, [chemical_name] => [weight] => 703.87 [form] => C38H57NO11 [cas] => NA [pslug] => 9as-3-hydroxy-3-2r-3r-6s-2-hydroxy-6-2s-3e-5e-7e-9s-11r-13s-14r-15e-14-hydroxy-2-13-dimethoxy-3-9-11-15-tetramethyl-12-17-dioxooctadeca-3-5-7-15-tetraen-1-yl-3-methyltetrahydro-2h-pyran-2-yl-tetrahydropyrido-2-1-c-1-4-oxazine-1-4-3h-6h-dione-pa180261012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0261012
Molecular Formula : C38H57NO11
Molecular Weight : 703.87
stdClass Object ( [pname] => Sirolimus-31,42-Diester Impurity [catalogue_number] => PA 18 0261013 [category_ids] => ,82,78,70,69, [chemical_name] => [weight] => 1146.42 [form] => C61H95NO19 [cas] => NA [pslug] => sirolimus-31-42-diester-impurity-pa180261013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0261013
Molecular Formula : C61H95NO19
Molecular Weight : 1146.42
stdClass Object ( [pname] => (3R,9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione [catalogue_number] => PA 18 0261015 [category_ids] => ,82,81,78,71,70,69, [chemical_name] => [weight] => 914.19 [form] => C51H79NO13 [cas] => NA [pslug] => 3r-9as-3-hydroxy-3-2r-3r-6s-2-hydroxy-6-2s-3e-5e-7e-9s-11r-13r-14r-15e-17r-19e-21r-14-hydroxy-22-1s-3r-4r-4-hydroxy-3-methoxycyclohexyl-2-13-dimethoxy-3-9-11-15-17-21-hexamethyl-12-18-dioxodocosa-3-5-7-15-19-pentaen-1-yl-3-methyltetrahydro-2h-pyran-2-yl-tetrahydropyrido-2-1-c-1-4-oxazine-1-4-3h-6h-dione-pa180261015 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0261015
Molecular Weight : 914.19
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