Rivaroxaban-impurities | Pharmaffiliates

rivaroxaban

An anticoagulant drug used to prevent blood clots. A direct factor Xa inhibitor which is taken by mouth. An oxazolidinone derivative and structurally similar to anibiotic Linezolid.Reference standards of Rivaroxaban API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Rivaroxaban - API Standards
    [catalogue_number] => PA 18 38000
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 366789-02-8
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PA 18 38000

Rivaroxaban - API Standards


  • Catalogue No.:PA 18 38000

  • CAS :

    366789-02-8

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => Rivaroxaban - Impurity E
    [catalogue_number] => PA 18 38510
    [category_ids] => ,69,70,71,78,82,88,
    [chemical_name] => 
    [weight] => 401.44
    [form] => C19H19N3O5S
    [cas] => 1415566-28-7
    [pslug] => 1415566-28-7-rivaroxaban-impurity-e-pa1838510
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PA 18 38510

Rivaroxaban - Impurity E


  • Catalogue No.:PA 18 38510

  • CAS :

    1415566-28-7

  • Molecular Formula : C19H19N3O5S

  • Molecular Weight : 401.44

stdClass Object
(
    [pname] => 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
    [catalogue_number] => PA 18 38670
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 395.41
    [form] => C21H21N3O5
    [cas] => 446292-07-5
    [pslug] => 446292-07-5-4-2r-hydroxy-3-phthalimido-propylamine-phenyl-3-morpholinone-pa1838670
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PA 18 38670

4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone


  • Catalogue No.:PA 18 38670

  • CAS :

    446292-07-5

  • Molecular Formula : C21H21N3O5

  • Molecular Weight : 395.41

stdClass Object
(
    [pname] => (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
    [catalogue_number] => PA 18 38680
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 931204-39-6
    [pslug] => 931204-39-6-s-2-2-4-5-5-chlorothiophene-2-carboxamido-methyl-2-oxooxazolidin-3-yl-phenyl-amino-ethoxy-acetic-acid-pa1838680
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PA 18 38680

(S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid


  • Catalogue No.:PA 18 38680

  • CAS :

    931204-39-6

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
(
    [pname] => 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone-d4
    [catalogue_number] => PA STI 050560
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 399.43
    [form] => C21H17D4N3O5
    [cas] => 1329838-35-8
    [pslug] => 1329838-35-8-4-2r-hydroxy-3-phthalimido-propylamine-phenyl-3-morpholinone-d4-pasti050560
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PA STI 050560

4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone-d4


  • Catalogue No.:PA STI 050560

  • CAS :

    1329838-35-8

  • Molecular Formula : C21H17D4N3O5

  • Molecular Weight : 399.43

stdClass Object
(
    [pname] => 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4
    [catalogue_number] => PA STI 073540
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 425.43
    [form] => C22H15D4N3O6
    [cas] => 1330180-09-0
    [pslug] => 1330180-09-0-4-4-5s-5-phthalimidomethyl-2-oxo-3-oxazolidinyl-phenyl-3-morpholinone-d4-pasti073540
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PA STI 073540

4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4


  • Catalogue No.:PA STI 073540

  • CAS :

    1330180-09-0

  • Molecular Formula : C22H15D4N3O6

  • Molecular Weight : 425.43

stdClass Object
(
    [pname] => Rivaroxaban-d4
    [catalogue_number] => PA STI 078220
    [category_ids] => ,69,71,98,78,70,82,88,
    [chemical_name] => 
    [weight] => 439.91
    [form] => C19H14D4ClN3O5S
    [cas] => 1132681-38-9
    [pslug] => 1132681-38-9-rivaroxaban-d4-pasti078220
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PA STI 078220

Rivaroxaban-d4


  • Catalogue No.:PA STI 078220

  • CAS :

    1132681-38-9

  • Molecular Formula : C19H14D4ClN3O5S

  • Molecular Weight : 439.91

stdClass Object
(
    [pname] => Rivaroxaban Diol (Mixture of Diastereomers)
    [catalogue_number] => PA 18 38565
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 1160170-00-2
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PA 18 38565

Rivaroxaban Diol (Mixture of Diastereomers)


  • Catalogue No.:PA 18 38565

  • CAS :

    1160170-00-2

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
(
    [pname] => 2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
    [catalogue_number] => PA 18 0381003
    [category_ids] => ,75,76,70,78,82,69,
    [chemical_name] => 
    [weight] => 239.66
    [form] => C11H10ClNO3
    [cas] => 148857-42-5
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PA 18 0381003

2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione


  • Catalogue No.:PA 18 0381003

  • CAS :

    148857-42-5

  • Molecular Formula : C11H10ClNO3

  • Molecular Weight : 239.66

stdClass Object
(
    [pname] => 5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381058
    [category_ids] => ,69,70,71,78,82,88,162,
    [chemical_name] => 
    [weight] => 438.88
    [form] => C18H19ClN4O5S
    [cas] => NA
    [pslug] => 5-chloro-n-2-hydroxy-3-nitroso-4-3-oxomorpholino-phenyl-amino-propyl-thiophene-2-carboxamide-pa180381058
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PA 18 0381058

5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381058

  • CAS :

    NA

  • Molecular Formula : C18H19ClN4O5S

  • Molecular Weight : 438.88

stdClass Object
(
    [pname] => Contezolid
    [catalogue_number] => PA 18 0381066
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 408.34
    [form] => C18H15F3N4O4
    [cas] => 1112968-42-9
    [pslug] => 1112968-42-9-contezolid-pa180381066
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PA 18 0381066

Contezolid


  • Catalogue No.:PA 18 0381066

  • CAS :

    1112968-42-9

  • Molecular Formula : C18H15F3N4O4

  • Molecular Weight : 408.34

stdClass Object
(
    [pname] => 5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381070
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 853.32
    [form] => C38H37ClN6O11S2
    [cas] => NA
    [pslug] => 5-chloro-n-4-s-5-5-hydroxythiophene-2-carboxamido-methyl-2-oxooxazolidin-3-yl-phenyl-n-2-2-oxo-2-s-2-oxo-3-4-3-oxomorpholino-phenyl-oxazolidin-5-yl-methyl-amino-ethoxy-ethyl-thiophene-2-carboxamide-pa180381070
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PA 18 0381070

5-Chloro-N-(4-((S)-5-((5-hydroxythiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381070

  • CAS :

    NA

  • Molecular Formula : C38H37ClN6O11S2

  • Molecular Weight : 853.32

stdClass Object
(
    [pname] => N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide
    [catalogue_number] => PA 18 0381071
    [category_ids] => ,69,78,70,82,
    [chemical_name] => 
    [weight] => 393.84
    [form] => C17H16ClN3O4S
    [cas] => 482306-93-4
    [pslug] => 482306-93-4-n-3-4-acetamidophenyl-2-oxooxazolidin-5-yl-methyl-5-chlorothiophene-2-carboxamide-pa180381071
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PA 18 0381071

N-((3-(4-Acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5-chlorothiophene-2-carboxamide


  • Catalogue No.:PA 18 0381071

  • CAS :

    482306-93-4

  • Molecular Formula : C17H16ClN3O4S

  • Molecular Weight : 393.84

stdClass Object
(
    [pname] => 2-Chloroisoindoline-1,3-dione
    [catalogue_number] => PA 18 0381072
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 181.58
    [form] => C8H4ClNO2
    [cas] => 3481-09-2
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PA 18 0381072

2-Chloroisoindoline-1,3-dione


  • Catalogue No.:PA 18 0381072

  • CAS :

    3481-09-2

  • Molecular Formula : C8H4ClNO2

  • Molecular Weight : 181.58

stdClass Object
(
    [pname] => Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
    [catalogue_number] => PA 18 0381075
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 1879903-65-7
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PA 18 0381075

Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity


  • Catalogue No.:PA 18 0381075

  • CAS :

    1879903-65-7

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => N-(3-Chloro-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous Amide
    [catalogue_number] => PA 18 0381076
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 313.74
    [form] => C13H16ClN3O4
    [cas] => NA
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PA 18 0381076

N-(3-Chloro-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous Amide


  • Catalogue No.:PA 18 0381076

  • CAS :

    NA

  • Molecular Formula : C13H16ClN3O4

  • Molecular Weight : 313.74

stdClass Object
(
    [pname] => N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
    [catalogue_number] => PA 18 0381081
    [category_ids] => ,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 424.41
    [form] => C21H20N4O6
    [cas] => NA
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PA 18 0381081

N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide


  • Catalogue No.:PA 18 0381081

  • CAS :

    NA

  • Molecular Formula : C21H20N4O6

  • Molecular Weight : 424.41