Sitagliptin-impurities | Pharmaffiliates

sitagliptin

Sitagliptin impurity B is also known as Defluoro Sitagliptin, an impurity of Sitagliptan, an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Reference standards of Sitagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (S)-Sitagliptin N-Boc-Acid Impurity
    [catalogue_number] => PA 19 48700
    [category_ids] => ,79,80,69,74,71,81,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 333.3
    [form] => C15H18F3NO4
    [cas] => 922178-94-7
    [pslug] => 922178-94-7-s-sitagliptin-n-boc-acid-impurity-pa1948700
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PA 19 48700

(S)-Sitagliptin N-Boc-Acid Impurity


  • Catalogue No.:PA 19 48700

  • CAS :

    922178-94-7

  • Molecular Formula : C15H18F3NO4

  • Molecular Weight : 333.3

stdClass Object
(
    [pname] => N-Boc-Sitagliptin
    [catalogue_number] => PA 19 48710
    [category_ids] => ,79,80,69,74,71,81,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 507.43
    [form] => C21H23F6N5O3
    [cas] => 486460-23-5
    [pslug] => 486460-23-5-n-boc-sitagliptin-pa1948710
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PA 19 48710

N-Boc-Sitagliptin


  • Catalogue No.:PA 19 48710

  • CAS :

    486460-23-5

  • Molecular Formula : C21H23F6N5O3

  • Molecular Weight : 507.43

stdClass Object
(
    [pname] => (S)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one (2R,3R)-2,3-bis(benzoyloxy)succinate
    [catalogue_number] => PA 19 48890
    [category_ids] => ,80,69,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 765.61
    [form] => C34H29F6N5O9
    [cas] => 1219440-27-3
    [pslug] => 1219440-27-3-s-3-amino-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-4-2-4-5-trifluorophenyl-butan-1-one-2r-3r-2-3-bis-benzoyloxy-succinate-pa1948890
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PA 19 48890

(S)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one (2R,3R)-2,3-bis(benzoyloxy)succinate


  • Catalogue No.:PA 19 48890

  • CAS :

    1219440-27-3

  • Molecular Formula : C34H29F6N5O9

  • Molecular Weight : 765.61

stdClass Object
(
    [pname] => 4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]
-1-(2,4,5-trifluorophenyl)butan-2-one-d4
    [catalogue_number] => PA STI 070760
    [category_ids] => ,80,69,71,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 410.31
    [form] => C16H8D4F6N4O2
    [cas] => NA
    [pslug] => 4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-
-1-2-4-5-trifluorophenyl-butan-2-one-d4-pasti070760
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PA STI 070760

4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl] -1-(2,4,5-trifluorophenyl)butan-2-one-d4


  • Catalogue No.:PA STI 070760

  • CAS :

    NA

  • Molecular Formula : C16H8D4F6N4O2

  • Molecular Weight : 410.31

stdClass Object
(
    [pname] => (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin
-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine-d4
    [catalogue_number] => PA STI 070770
    [category_ids] => ,80,69,71,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 409.32
    [form] => C16H9D4F6N5O
    [cas] => 1620233-76-2
    [pslug] => 1620233-76-2-2z-4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin
-7-8h-yl-1-2-4-5-trifluorophenyl-but-2-en-2-amine-d4-pasti070770
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PA STI 070770

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine-d4


  • Catalogue No.:PA STI 070770

  • CAS :

    1620233-76-2

  • Molecular Formula : C16H9D4F6N5O

  • Molecular Weight : 409.32

stdClass Object
(
    [pname] => Sitagliptin-d4 Phosphate
    [catalogue_number] => PA STI 079340
    [category_ids] => ,80,69,71,75,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 509.33
    [form] => C16H14D4F6N5O5P
    [cas] => 1432063-88-1
    [pslug] => 1432063-88-1-sitagliptin-d4-phosphate-pasti079340
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PA STI 079340

Sitagliptin-d4 Phosphate


  • Catalogue No.:PA STI 079340

  • CAS :

    1432063-88-1

  • Molecular Formula : C16H14D4F6N5O5P

  • Molecular Weight : 509.33

stdClass Object
(
    [pname] => ent-Sitagliptin-d4 Phosphate
    [catalogue_number] => PA STI 079350
    [category_ids] => ,80,69,71,75,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 509.33
    [form] => C16H14D4F6N5O5P
    [cas] => NA
    [pslug] => ent-sitagliptin-d4-phosphate-pasti079350
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PA STI 079350

ent-Sitagliptin-d4 Phosphate


  • Catalogue No.:PA STI 079350

  • CAS :

    NA

  • Molecular Formula : C16H14D4F6N5O5P

  • Molecular Weight : 509.33

stdClass Object
(
    [pname] => Sitagliptin Tablets EP Impurity FP-E (Hydrochloride Salt)
    [catalogue_number] => PA 19 48980
    [category_ids] => 80,79,69,70,82,78
    [chemical_name] => 
    [weight] => 269.65
    [form] => C10H11ClF3NO2
    [cas] => 1204818-19-8
    [pslug] => 1204818-19-8-sitagliptin-tablets-ep-impurity-fp-e-hydrochloride-salt-pa1948980
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PA 19 48980

Sitagliptin Tablets EP Impurity FP-E (Hydrochloride Salt)


  • Catalogue No.:PA 19 48980

  • CAS :

    1204818-19-8

  • Molecular Formula : C10H11ClF3NO2

  • Molecular Weight : 269.65

stdClass Object
(
    [pname] => (S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 0481067
    [category_ids] => ,69,79,75,
    [chemical_name] => 
    [weight] => 233.19
    [form] => C10H10F3NO2
    [cas] => 1217854-08-4
    [pslug] => 1217854-08-4-s-3-amino-4-2-4-5-trifluorophenyl-butanoic-acid-pa190481067
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PA 19 0481067

(S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 0481067

  • CAS :

    1217854-08-4

  • Molecular Formula : C10H10F3NO2

  • Molecular Weight : 233.19

stdClass Object
(
    [pname] => 3-Nitroso-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
    [catalogue_number] => PA 19 0481072
    [category_ids] => ,69,70,78,82,162,
    [chemical_name] => 
    [weight] => 421.3
    [form] => C16H13F6N5O2
    [cas] => NA
    [pslug] => 3-nitroso-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-4-2-4-5-trifluorophenyl-butan-1-one-pa190481072
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PA 19 0481072

3-Nitroso-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one


  • Catalogue No.:PA 19 0481072

  • CAS :

    NA

  • Molecular Formula : C16H13F6N5O2

  • Molecular Weight : 421.3

stdClass Object
(
    [pname] => N,N-Diisopropyl-3-oxo-4-(2,4,5-trifluorophenyl)butanamide
    [catalogue_number] => PA 19 0481093
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.34
    [form] => C16H20F3NO2
    [cas] => NA
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PA 19 0481093

N,N-Diisopropyl-3-oxo-4-(2,4,5-trifluorophenyl)butanamide


  • Catalogue No.:PA 19 0481093

  • CAS :

    NA

  • Molecular Formula : C16H20F3NO2

  • Molecular Weight : 315.34

stdClass Object
(
    [pname] => (R)-10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-5,6,9,10-tetrahydro-8H-[1,2,4]triazolo[3',4':3,4]pyrazino[1,2-a]pyrimidin-8-one
    [catalogue_number] => PA 19 0481094
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 403.29
    [form] => C16H11F6N5O
    [cas] => 2821750-76-7
    [pslug] => 2821750-76-7-r-10-2-4-5-trifluorobenzyl-3-trifluoromethyl-5-6-9-10-tetrahydro-8h-1-2-4-triazolo-3-4-3-4-pyrazino-1-2-a-pyrimidin-8-one-pa190481094
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PA 19 0481094

(R)-10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-5,6,9,10-tetrahydro-8H-[1,2,4]triazolo[3',4':3,4]pyrazino[1,2-a]pyrimidin-8-one


  • Catalogue No.:PA 19 0481094

  • CAS :

    2821750-76-7

  • Molecular Formula : C16H11F6N5O

  • Molecular Weight : 403.29