Ibrutinib-impurities | Pharmaffiliates

ibrutinib

Ibrutinib is used to treat chronic lymphocytic leukemia Waldenström's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease. It is a small molecule drug. Reference standards of Ibrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Ibrutinib - API Standards 
    [catalogue_number] => PA 09 27000
    [category_ids] => ,79,80,81,78,
    [chemical_name] => 
    [weight] => 440.50
    [form] => C25H24N6O2
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PA 09 27000

Ibrutinib - API Standards


  • Catalogue No.:PA 09 27000

  • CAS :

    936563-96-1

  • Molecular Formula : C25H24N6O2

  • Molecular Weight : 440.50

20% OFF
stdClass Object
(
    [pname] => (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    [catalogue_number] => PA 09 27560
    [category_ids] => ,79,80,81,
    [chemical_name] => 
    [weight] => 386.45
    [form] => C22H22N6O
    [cas] => 1022150-12-4
    [pslug] => 1022150-12-4-r-3-4-phenoxyphenyl-1-piperidin-3-yl-1h-pyrazolo-3-4-d-pyrimidin-4-amine-pa0927560
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PA 09 27560

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine


  • Catalogue No.:PA 09 27560

  • CAS :

    1022150-12-4

  • Molecular Formula : C22H22N6O

  • Molecular Weight : 386.45

stdClass Object
(
    [pname] => 1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one
    [catalogue_number] => PA 09 27510
    [category_ids] => ,71,79,80,81,75,78,70,82,
    [chemical_name] => 
    [weight] => 826.95
    [form] => C47H46N12O3
    [cas] => 1987905-93-0
    [pslug] => 1987905-93-0-1-3-bis-r-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-propan-1-one-pa0927510
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PA 09 27510

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one


  • Catalogue No.:PA 09 27510

  • CAS :

    1987905-93-0

  • Molecular Formula : C47H46N12O3

  • Molecular Weight : 826.95

stdClass Object
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    [pname] => (R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate
    [catalogue_number] => PA 09 27520
    [category_ids] => ,71,79,80,81,75,78,70,82,
    [chemical_name] => 
    [weight] => 512.56
    [form] => C28H28N6O4
    [cas] => 2244619-11-0
    [pslug] => 2244619-11-0-r-3-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-3-oxopropyl-acrylate-pa0927520
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PA 09 27520

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate


  • Catalogue No.:PA 09 27520

  • CAS :

    2244619-11-0

  • Molecular Formula : C28H28N6O4

  • Molecular Weight : 512.56

stdClass Object
(
    [pname] => 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one
    [catalogue_number] => PA 09 27530
    [category_ids] => 82,81,80,79,78,75,71,70
    [chemical_name] => 
    [weight] => 880.99
    [form] => C50H48N12O4
    [cas] => 2031255-23-7
    [pslug] => 2031255-23-7-1-3r-3-4-amino-3-4-phenoxyphenyl-pyrazolo-3-4-d-pyrimidin-1-yl-1-piperidyl-3-1r-3-4-phenoxyphenyl-1-1-prop-2-enoyl-3-piperidyl-pyrazolo-3-4-d-pyrimidin-4-yl-amino-propan-1-one-pa0927530
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PA 09 27530

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one


  • Catalogue No.:PA 09 27530

  • CAS :

    2031255-23-7

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 880.99

stdClass Object
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    [pname] => (S)-Ibrutinib
    [catalogue_number] => PA 09 27540
    [category_ids] => ,79,80,81,
    [chemical_name] => 
    [weight] => 440.5
    [form] => C25H24N6O2
    [cas] => 936563-97-2
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PA 09 27540

(S)-Ibrutinib


  • Catalogue No.:PA 09 27540

  • CAS :

    936563-97-2

  • Molecular Formula : C25H24N6O2

  • Molecular Weight : 440.5

stdClass Object
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    [pname] => (E)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one
    [catalogue_number] => PA 09 27570
    [category_ids] => ,79,80,81,
    [chemical_name] => 
    [weight] => 456.5
    [form] => C25H24N6O3
    [cas] => NA
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PA 09 27570

(E)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one


  • Catalogue No.:PA 09 27570

  • CAS :

    NA

  • Molecular Formula : C25H24N6O3

  • Molecular Weight : 456.5

stdClass Object
(
    [pname] => N-(1-((S)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-((S)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanamide
    [catalogue_number] => PA 09 27580
    [category_ids] => ,79,80,81,71,
    [chemical_name] => 
    [weight] => 881.01
    [form] => C50H48N12O4
    [cas] => NA
    [pslug] => n-1-s-1-acryloylpiperidin-3-yl-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-4-yl-3-s-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-propanamide-pa0927580
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PA 09 27580

N-(1-((S)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-((S)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanamide


  • Catalogue No.:PA 09 27580

  • CAS :

    NA

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

stdClass Object
(
    [pname] => Ibrutinib-d5
    [catalogue_number] => PA STI 052370
    [category_ids] => ,79,80,81,98,
    [chemical_name] => 
    [weight] => 445.53
    [form] => C25H19D5N6O2
    [cas] => 1553977-17-5
    [pslug] => 1553977-17-5-ibrutinib-d5-pasti052370
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PA STI 052370

Ibrutinib-d5


  • Catalogue No.:PA STI 052370

  • CAS :

    1553977-17-5

  • Molecular Formula : C25H19D5N6O2

  • Molecular Weight : 445.53

stdClass Object
(
    [pname] => (S)-Ibrutinib-d5
    [catalogue_number] => PA STI 052380
    [category_ids] => ,79,80,81,98,
    [chemical_name] => 
    [weight] => 445.53
    [form] => C25H19D5N6O2
    [cas] => NA
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PA STI 052380

(S)-Ibrutinib-d5


  • Catalogue No.:PA STI 052380

  • CAS :

    NA

  • Molecular Formula : C25H19D5N6O2

  • Molecular Weight : 445.53

stdClass Object
(
    [pname] => (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one
    [catalogue_number] => PA 09 0271003
    [category_ids] => ,75,81,123,76,78,82,
    [chemical_name] => 
    [weight] => 476.97
    [form] => C25H25ClN6O2
    [cas] => 1288338-96-4
    [pslug] => 1288338-96-4-r-1-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-3-chloropropan-1-one-pa090271003
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PA 09 0271003

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one


  • Catalogue No.:PA 09 0271003

  • CAS :

    1288338-96-4

  • Molecular Formula : C25H25ClN6O2

  • Molecular Weight : 476.97

stdClass Object
(
    [pname] => (R,Z)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one
    [catalogue_number] => PA 09 0271022
    [category_ids] => ,79,80,81,78,75,76,
    [chemical_name] => 
    [weight] => 456.51
    [form] => C25H24N6O3
    [cas] => NA
    [pslug] => r-z-1-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-3-hydroxyprop-2-en-1-one-pa090271022
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PA 09 0271022

(R,Z)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one


  • Catalogue No.:PA 09 0271022

  • CAS :

    NA

  • Molecular Formula : C25H24N6O3

  • Molecular Weight : 456.51

stdClass Object
(
    [pname] => Ibrutinib Racemate
    [catalogue_number] => PA 09 0271023
    [category_ids] => ,79,80,81,78,
    [chemical_name] => 
    [weight] => 440.51
    [form] => C25H24N6O2
    [cas] => 936563-87-0
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PA 09 0271023

Ibrutinib Racemate


  • Catalogue No.:PA 09 0271023

  • CAS :

    936563-87-0

  • Molecular Formula : C25H24N6O2

  • Molecular Weight : 440.51

stdClass Object
(
    [pname] => Ibrutinib Diacrylate Analog Impurity
    [catalogue_number] => PA 09 0271024
    [category_ids] => ,79,80,81,78,
    [chemical_name] => 
    [weight] => 494.56
    [form] => C28H26N6O3
    [cas] => NA
    [pslug] => ibrutinib-diacrylate-analog-impurity-pa090271024
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PA 09 0271024

Ibrutinib Diacrylate Analog Impurity


  • Catalogue No.:PA 09 0271024

  • CAS :

    NA

  • Molecular Formula : C28H26N6O3

  • Molecular Weight : 494.56

stdClass Object
(
    [pname] => 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea
    [catalogue_number] => PA 09 0271025
    [category_ids] => ,79,80,81,78,
    [chemical_name] => 
    [weight] => 597.68
    [form] => C31H35N9O4
    [cas] => 2142634-18-0
    [pslug] => 2142634-18-0-1-4-4-amino-3-4-2-morpholinoethoxy-phenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-phenyl-3-5-tert-butyl-isoxazol-3-yl-urea-pa090271025
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PA 09 0271025

1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea


  • Catalogue No.:PA 09 0271025

  • CAS :

    2142634-18-0

  • Molecular Formula : C31H35N9O4

  • Molecular Weight : 597.68