Sitagliptin-impurities | Pharmaffiliates

sitagliptin

Sitagliptin impurity B is also known as Defluoro Sitagliptin, an impurity of Sitagliptan, an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Reference standards of Sitagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Sitagliptin Enamine Impurity
    [catalogue_number] => PA 19 48660
    [category_ids] => ,71,70,81,78,70,82,
    [chemical_name] => 
    [weight] => 405.3
    [form] => C16H13F6N5O
    [cas] => 767340-03-4
    [pslug] => 767340-03-4-sitagliptin-enamine-impurity-pa1948660
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PA 19 48660

Sitagliptin Enamine Impurity


  • Catalogue No.:PA 19 48660

  • CAS :

    767340-03-4

  • Molecular Formula : C16H13F6N5O

  • Molecular Weight : 405.3

stdClass Object
(
    [pname] => (S)-Sitagliptin N-Boc-Acid Impurity
    [catalogue_number] => PA 19 48700
    [category_ids] => ,79,80,69,74,71,81,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 333.3
    [form] => C15H18F3NO4
    [cas] => 922178-94-7
    [pslug] => 922178-94-7-s-sitagliptin-n-boc-acid-impurity-pa1948700
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PA 19 48700

(S)-Sitagliptin N-Boc-Acid Impurity


  • Catalogue No.:PA 19 48700

  • CAS :

    922178-94-7

  • Molecular Formula : C15H18F3NO4

  • Molecular Weight : 333.3

stdClass Object
(
    [pname] => N-Boc-Sitagliptin
    [catalogue_number] => PA 19 48710
    [category_ids] => ,79,80,69,74,71,81,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 507.43
    [form] => C21H23F6N5O3
    [cas] => 486460-23-5
    [pslug] => 486460-23-5-n-boc-sitagliptin-pa1948710
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PA 19 48710

N-Boc-Sitagliptin


  • Catalogue No.:PA 19 48710

  • CAS :

    486460-23-5

  • Molecular Formula : C21H23F6N5O3

  • Molecular Weight : 507.43

stdClass Object
(
    [pname] => Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate
    [catalogue_number] => PA 19 48780
    [category_ids] => ,92,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 287.23
    [form] => C13H12F3NO3
    [cas] => 1234321-81-3
    [pslug] => 1234321-81-3-methyl-3-acetamido-4-2-4-5-trifluorophenyl-but-2-enoate-pa1948780
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PA 19 48780

Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate


  • Catalogue No.:PA 19 48780

  • CAS :

    1234321-81-3

  • Molecular Formula : C13H12F3NO3

  • Molecular Weight : 287.23

stdClass Object
(
    [pname] => (3R,3'R)-N,N'-(Ethane-1,2-diyl)bis(3-amino-4-(2,4,5-trifluorophenyl)butanamide)
    [catalogue_number] => PA 19 48790
    [category_ids] => ,92,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 490.44
    [form] => C22H24F6N4O2
    [cas] => 1608491-98-0
    [pslug] => 1608491-98-0-3r-3r-n-n-ethane-1-2-diyl-bis-3-amino-4-2-4-5-trifluorophenyl-butanamide-pa1948790
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PA 19 48790

(3R,3'R)-N,N'-(Ethane-1,2-diyl)bis(3-amino-4-(2,4,5-trifluorophenyl)butanamide)


  • Catalogue No.:PA 19 48790

  • CAS :

    1608491-98-0

  • Molecular Formula : C22H24F6N4O2

  • Molecular Weight : 490.44

stdClass Object
(
    [pname] => 3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
    [catalogue_number] => PA 19 48800
    [category_ids] => ,71,75,81,78,70,82,79,
    [chemical_name] => 
    [weight] => 206.13
    [form] => C6H5F3N4O
    [cas] => 877402-45-4
    [pslug] => 877402-45-4-3-trifluoromethyl-6-7-dihydro-1-2-4-triazolo-4-3-a-pyrazin-8-5h-one-pa1948800
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PA 19 48800

3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one


  • Catalogue No.:PA 19 48800

  • CAS :

    877402-45-4

  • Molecular Formula : C6H5F3N4O

  • Molecular Weight : 206.13

stdClass Object
(
    [pname] => (R,E)-3-Amino-N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)but-2-enamide
    [catalogue_number] => PA 19 48810
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 620.47
    [form] => C26H21F9N6O2
    [cas] => NA
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PA 19 48810

(R,E)-3-Amino-N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)but-2-enamide


  • Catalogue No.:PA 19 48810

  • CAS :

    NA

  • Molecular Formula : C26H21F9N6O2

  • Molecular Weight : 620.47

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48820
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 315.31
    [form] => C15H19F2NO4
    [cas] => 851307-12-5
    [pslug] => 851307-12-5-r-3-tert-butoxycarbonyl-amino-4-2-4-difluorophenyl-butanoic-acid-pa1948820
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PA 19 48820

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48820

  • CAS :

    851307-12-5

  • Molecular Formula : C15H19F2NO4

  • Molecular Weight : 315.31

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48830
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 315.31
    [form] => C15H19F2NO4
    [cas] => 486459-98-7
    [pslug] => 486459-98-7-r-3-tert-butoxycarbonyl-amino-4-2-5-difluorophenyl-butanoic-acid-pa1948830
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PA 19 48830

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48830

  • CAS :

    486459-98-7

  • Molecular Formula : C15H19F2NO4

  • Molecular Weight : 315.31

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(3,4-difluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48840
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 315.31
    [form] => C15H19F2NO4
    [cas] => 269396-59-0
    [pslug] => 269396-59-0-r-3-tert-butoxycarbonyl-amino-4-3-4-difluorophenyl-butanoic-acid-pa1948840
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PA 19 48840

(R)-3-((tert-Butoxycarbonyl)amino)-4-(3,4-difluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48840

  • CAS :

    269396-59-0

  • Molecular Formula : C15H19F2NO4

  • Molecular Weight : 315.31

stdClass Object
(
    [pname] => Boc-D-β-homophenylalanine
    [catalogue_number] => PA 19 48850
    [category_ids] => ,80,71,75,81,78,70,82,79,
    [chemical_name] => 
    [weight] => 279.33
    [form] => C15H21NO4
    [cas] => 101555-61-7
    [pslug] => 101555-61-7-boc-d-beta-homophenylalanine-pa1948850
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PA 19 48850

Boc-D-β-homophenylalanine


  • Catalogue No.:PA 19 48850

  • CAS :

    101555-61-7

  • Molecular Formula : C15H21NO4

  • Molecular Weight : 279.33

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48860
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 297.32
    [form] => C15H20FNO4
    [cas] => 331763-66-7
    [pslug] => 331763-66-7-r-3-tert-butoxycarbonyl-amino-4-3-fluorophenyl-butanoic-acid-pa1948860
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PA 19 48860

(R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48860

  • CAS :

    331763-66-7

  • Molecular Formula : C15H20FNO4

  • Molecular Weight : 297.32

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48870
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 297.32
    [form] => C15H20FNO4
    [cas] => 218608-98-1
    [pslug] => 218608-98-1-r-3-tert-butoxycarbonyl-amino-4-2-fluorophenyl-butanoic-acid-pa1948870
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PA 19 48870

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48870

  • CAS :

    218608-98-1

  • Molecular Formula : C15H20FNO4

  • Molecular Weight : 297.32

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(4-fluorophenyl)butanoic Acid
    [catalogue_number] => PA 19 48880
    [category_ids] => ,80,71,75,81,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 297.32
    [form] => C15H20FNO4
    [cas] => 218609-00-8
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PA 19 48880

(R)-3-((tert-Butoxycarbonyl)amino)-4-(4-fluorophenyl)butanoic Acid


  • Catalogue No.:PA 19 48880

  • CAS :

    218609-00-8

  • Molecular Formula : C15H20FNO4

  • Molecular Weight : 297.32

stdClass Object
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    [pname] => (S)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one (2R,3R)-2,3-bis(benzoyloxy)succinate
    [catalogue_number] => PA 19 48890
    [category_ids] => ,80,69,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 765.61
    [form] => C34H29F6N5O9
    [cas] => 1219440-27-3
    [pslug] => 1219440-27-3-s-3-amino-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-4-2-4-5-trifluorophenyl-butan-1-one-2r-3r-2-3-bis-benzoyloxy-succinate-pa1948890
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PA 19 48890

(S)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one (2R,3R)-2,3-bis(benzoyloxy)succinate


  • Catalogue No.:PA 19 48890

  • CAS :

    1219440-27-3

  • Molecular Formula : C34H29F6N5O9

  • Molecular Weight : 765.61

stdClass Object
(
    [pname] => N-Acetyl Sitagliptin-d3
    [catalogue_number] => PA STI 003510
    [category_ids] => ,80,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 452.37
    [form] => C18H13D3F6N5O2
    [cas] => 1795785-80-6
    [pslug] => 1795785-80-6-n-acetyl-sitagliptin-d3-pasti003510
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PA STI 003510

N-Acetyl Sitagliptin-d3


  • Catalogue No.:PA STI 003510

  • CAS :

    1795785-80-6

  • Molecular Formula : C18H13D3F6N5O2

  • Molecular Weight : 452.37

stdClass Object
(
    [pname] => 4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]
-1-(2,4,5-trifluorophenyl)butan-2-one-d4
    [catalogue_number] => PA STI 070760
    [category_ids] => ,80,69,71,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 410.31
    [form] => C16H8D4F6N4O2
    [cas] => NA
    [pslug] => 4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-
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PA STI 070760

4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl] -1-(2,4,5-trifluorophenyl)butan-2-one-d4


  • Catalogue No.:PA STI 070760

  • CAS :

    NA

  • Molecular Formula : C16H8D4F6N4O2

  • Molecular Weight : 410.31

stdClass Object
(
    [pname] => (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin
-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine-d4
    [catalogue_number] => PA STI 070770
    [category_ids] => ,80,69,71,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 409.32
    [form] => C16H9D4F6N5O
    [cas] => 1620233-76-2
    [pslug] => 1620233-76-2-2z-4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin
-7-8h-yl-1-2-4-5-trifluorophenyl-but-2-en-2-amine-d4-pasti070770
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PA STI 070770

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine-d4


  • Catalogue No.:PA STI 070770

  • CAS :

    1620233-76-2

  • Molecular Formula : C16H9D4F6N5O

  • Molecular Weight : 409.32

stdClass Object
(
    [pname] => Sitagliptin-d4 Phosphate
    [catalogue_number] => PA STI 079340
    [category_ids] => ,80,69,71,75,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 509.33
    [form] => C16H14D4F6N5O5P
    [cas] => 1432063-88-1
    [pslug] => 1432063-88-1-sitagliptin-d4-phosphate-pasti079340
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PA STI 079340

Sitagliptin-d4 Phosphate


  • Catalogue No.:PA STI 079340

  • CAS :

    1432063-88-1

  • Molecular Formula : C16H14D4F6N5O5P

  • Molecular Weight : 509.33

stdClass Object
(
    [pname] => ent-Sitagliptin-d4 Phosphate
    [catalogue_number] => PA STI 079350
    [category_ids] => ,80,69,71,75,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 509.33
    [form] => C16H14D4F6N5O5P
    [cas] => NA
    [pslug] => ent-sitagliptin-d4-phosphate-pasti079350
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PA STI 079350

ent-Sitagliptin-d4 Phosphate


  • Catalogue No.:PA STI 079350

  • CAS :

    NA

  • Molecular Formula : C16H14D4F6N5O5P

  • Molecular Weight : 509.33