A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Sorafenib - API Standards [catalogue_number] => PA 46 17000 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 464.82 [form] => C21H16ClF3N4O3 [cas] => 284461-73-0 [pslug] => 284461-73-0-sorafenib-api-pa4617000 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17000
CAS :
Molecular Formula : C21H16ClF3N4O3
Molecular Weight : 464.82
stdClass Object ( [pname] => 2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid [catalogue_number] => PA 46 17510 [category_ids] => 82,81,79,78,70 [chemical_name] => [weight] => 635.01 [form] => C28H22ClF3N4O6S [cas] => NA [pslug] => 2-4-4-3-2-chloro-3-trifluoromethyl-phenyl-ureido-phenoxy-6-methylpicolinamido-4-methylbenzenesulfonic-acid-pa4617510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17510
Molecular Formula : C28H22ClF3N4O6S
Molecular Weight : 635.01
stdClass Object ( [pname] => Sorafenib-d3 [catalogue_number] => PA STI 079660 [category_ids] => ,81,98,78,70,82, [chemical_name] => [weight] => 467.84 [form] => C21H13D3ClF3N4O3 [cas] => 1130115-44-4 [pslug] => 1130115-44-4-sorafenib-d3-pasti079660 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 079660
Molecular Formula : C21H13D3ClF3N4O3
Molecular Weight : 467.84
stdClass Object ( [pname] => N-Desmethyl Sorafenib [catalogue_number] => PA 46 17630 [category_ids] => ,79,80,71,81,78,70,82, [chemical_name] => [weight] => 450.8 [form] => C20H14ClF3N4O3 [cas] => 284461-74-1 [pslug] => 284461-74-1-n-desmethyl-sorafenib-pa4617630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 17630
Molecular Formula : C20H14ClF3N4O3
Molecular Weight : 450.8
stdClass Object ( [pname] => Methyl 4-(4-aminophenoxy)picolinate [catalogue_number] => PA 46 0171012 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 244.25 [form] => C13H12N2O3 [cas] => 757251-59-5 [pslug] => 757251-59-5-methyl-4-4-aminophenoxy-picolinate-pa460171012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 0171012
Molecular Formula : C13H12N2O3
Molecular Weight : 244.25
stdClass Object ( [pname] => Sorafenib Carboxylic Acid Methyl Ester [catalogue_number] => PA 46 0171013 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 465.81 [form] => C21H15ClF3N3O4 [cas] => 573673-43-5 [pslug] => 573673-43-5-sorafenib-carboxylic-acid-methyl-ester-pa460171013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 0171013
Molecular Formula : C21H15ClF3N3O4
Molecular Weight : 465.81
stdClass Object ( [pname] => 1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea [catalogue_number] => PA 46 0171015 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 389.42 [form] => C18H26F3N3O3 [cas] => 1567296-47-2 [pslug] => 1567296-47-2-1-4-ethoxy-3-trifluoromethyl-phenyl-3-2-3-hydroxymethyl-piperidin-1-yl-ethyl-urea-pa460171015 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 0171015
Molecular Formula : C18H26F3N3O3
Molecular Weight : 389.42
stdClass Object ( [pname] => N-Methyl-4-(methylamino)picolinamide [catalogue_number] => PA 46 0171016 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 165.2 [form] => C8H11N3O [cas] => 1065074-98-7 [pslug] => 1065074-98-7-n-methyl-4-methylamino-picolinamide-pa460171016 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 0171016
Molecular Formula : C8H11N3O
Molecular Weight : 165.2
stdClass Object ( [pname] => 4,6-Dichloro-N-methylpicolinamide [catalogue_number] => PA 46 0171017 [category_ids] => ,79,81,78,70,82, [chemical_name] => [weight] => 205.04 [form] => C7H6Cl2N2O [cas] => 1379324-09-0 [pslug] => 1379324-09-0-4-6-dichloro-n-methylpicolinamide-pa460171017 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 46 0171017
Molecular Formula : C7H6Cl2N2O
Molecular Weight : 205.04
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