Doxorubicin-impurities | Pharmaffiliates

doxorubicin

Doxorubicin is commonly used to treat some leukemias and Hodgkin's lymphoma, as well as cancers of the bladder, breast, stomach, lung, ovaries, thyroid, soft tissue sarcoma, multiple myeloma, and others. It is sold under the trade names Adriamycin.. Reference standards of Doxorubicin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Doxorubicinol (mixture of diasteromers)
    [catalogue_number] => PA 04 45510
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 545.55
    [form] => C27H31NO11
    [cas] => NA
    [pslug] => doxorubicinol-mixture-of-diasteromers-pa0445510
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PA 04 45510

Doxorubicinol (mixture of diasteromers)


  • Catalogue No.:PA 04 45510

  • CAS :

    NA

  • Molecular Formula : C27H31NO11

  • Molecular Weight : 545.55

stdClass Object
(
    [pname] => 7,8-Desacetyl-9,10-dehydro Daunorubicinone
    [catalogue_number] => PA 04 45520
    [category_ids] => ,80,75,78,70,82,
    [chemical_name] => 
    [weight] => 352.29
    [form] => C19H12O7
    [cas] => 1159977-24-8
    [pslug] => 1159977-24-8-7-8-desacetyl-9-10-dehydro-daunorubicinone-pa0445520
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PA 04 45520

7,8-Desacetyl-9,10-dehydro Daunorubicinone


  • Catalogue No.:PA 04 45520

  • CAS :

    1159977-24-8

  • Molecular Formula : C19H12O7

  • Molecular Weight : 352.29

stdClass Object
(
    [pname] => Doxorubicin Olefin Impurity
    [catalogue_number] => PA 04 45550
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 511.48
    [form] => C26H25NO10
    [cas] => NA
    [pslug] => doxorubicin-olefin-impurity-pa0445550
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PA 04 45550

Doxorubicin Olefin Impurity


  • Catalogue No.:PA 04 45550

  • CAS :

    NA

  • Molecular Formula : C26H25NO10

  • Molecular Weight : 511.48

stdClass Object
(
    [pname] => 7,8,9,10-Dehydro Doxorubicinone
    [catalogue_number] => PA 04 45580
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 394.33
    [form] => C21H14O8
    [cas] => 1159977-23-7
    [pslug] => 1159977-23-7-7-8-9-10-dehydro-doxorubicinone-pa0445580
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PA 04 45580

7,8,9,10-Dehydro Doxorubicinone


  • Catalogue No.:PA 04 45580

  • CAS :

    1159977-23-7

  • Molecular Formula : C21H14O8

  • Molecular Weight : 394.33

stdClass Object
(
    [pname] => 14-Hydroxy Carminomycin
    [catalogue_number] => PA 04 45590
    [category_ids] => ,80,91,78,70,82,
    [chemical_name] => 
    [weight] => 529.49
    [form] => C26H27NO11
    [cas] => 69401-50-9
    [pslug] => 69401-50-9-14-hydroxy-carminomycin-pa0445590
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PA 04 45590

14-Hydroxy Carminomycin


  • Catalogue No.:PA 04 45590

  • CAS :

    69401-50-9

  • Molecular Formula : C26H27NO11

  • Molecular Weight : 529.49

stdClass Object
(
    [pname] => N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-6-(2,5-dioxopyrrol-1-yl)hexanamide
    [catalogue_number] => PA 04 45600
    [category_ids] => ,79,80,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 750.7
    [form] => C37H42N4O13
    [cas] => 1361644-26-9
    [pslug] => 1361644-26-9-n-e-1-2s-4s-4-2r-4s-5s-6s-4-amino-5-hydroxy-6-methyloxan-2-yl-oxy-2-5-12-trihydroxy-7-methoxy-6-11-dioxo-3-4-dihydro-1h-tetracen-2-yl-2-hydroxyethylidene-amino-6-2-5-dioxopyrrol-1-yl-hexanamide-pa0445600
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PA 04 45600

N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-6-(2,5-dioxopyrrol-1-yl)hexanamide


  • Catalogue No.:PA 04 45600

  • CAS :

    1361644-26-9

  • Molecular Formula : C37H42N4O13

  • Molecular Weight : 750.7

stdClass Object
(
    [pname] => Doxorubicinol
    [catalogue_number] => PA 04 45610
    [category_ids] => ,79,80,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 545.54
    [form] => C27H31NO11
    [cas] => 54193-28-1
    [pslug] => 54193-28-1-doxorubicinol-pa0445610
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PA 04 45610

Doxorubicinol


  • Catalogue No.:PA 04 45610

  • CAS :

    54193-28-1

  • Molecular Formula : C27H31NO11

  • Molecular Weight : 545.54

stdClass Object
(
    [pname] => 7-Deoxy Doxorubicinol Aglycone-13C,d3 (Mixture of Diastereomers)
    [catalogue_number] => PA STI 026160
    [category_ids] => ,69,70,75,76,78,82,98,
    [chemical_name] => 
    [weight] => 404.39
    [form] => C21H17D3O8
    [cas] => NA
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PA STI 026160

7-Deoxy Doxorubicinol Aglycone-13C,d3 (Mixture of Diastereomers)


  • Catalogue No.:PA STI 026160

  • CAS :

    NA

  • Molecular Formula : C21H17D3O8

  • Molecular Weight : 404.39

stdClass Object
(
    [pname] => Doxorubicin-13C,d3 (approximately 50% pure, contains unidentified salts)
    [catalogue_number] => PA STI 036350
    [category_ids] => ,70,78,82,98,
    [chemical_name] => 
    [weight] => 547.53
    [form] => C2613CH26D3NO11
    [cas] => NA
    [pslug] => doxorubicin-13c-d3-approximately-50percentage-pure-contains-unidentified-salts-pasti036350
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PA STI 036350

Doxorubicin-13C,d3 (approximately 50% pure, contains unidentified salts)


  • Catalogue No.:PA STI 036350

  • CAS :

    NA

  • Molecular Formula : C2613CH26D3NO11

  • Molecular Weight : 547.53

stdClass Object
(
    [pname] => Doxorubicinone-d3
    [catalogue_number] => PA STI 036370
    [category_ids] => ,70,75,76,78,82,98,
    [chemical_name] => 
    [weight] => 417.38
    [form] => C21H15D3O9
    [cas] => NA
    [pslug] => doxorubicinone-d3-pasti036370
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PA STI 036370

Doxorubicinone-d3


  • Catalogue No.:PA STI 036370

  • CAS :

    NA

  • Molecular Formula : C21H15D3O9

  • Molecular Weight : 417.38

stdClass Object
(
    [pname] => 14-Chloro Daunorubicin
    [catalogue_number] => PA 04 45640
    [category_ids] => ,74,78,70,82,
    [chemical_name] => 
    [weight] => 561.97
    [form] => C27H28ClNO10
    [cas] => 121250-06-4
    [pslug] => 121250-06-4-14-chloro-daunorubicin-pa0445640
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PA 04 45640

14-Chloro Daunorubicin


  • Catalogue No.:PA 04 45640

  • CAS :

    121250-06-4

  • Molecular Formula : C27H28ClNO10

  • Molecular Weight : 561.97

stdClass Object
(
    [pname] => (8S-cis)-8-Acetyl-10-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
    [catalogue_number] => PA 04 45660
    [category_ids] => ,69,91,71,78,70,82,
    [chemical_name] => 
    [weight] => 512.19
    [form] => C27H32O8Si
    [cas] => 111248-01-2
    [pslug] => 111248-01-2-8s-cis-8-acetyl-10-1-1-dimethylethyl-dimethylsilyl-oxy-7-8-9-10-tetrahydro-6-8-11-trihydroxy-1-methoxy-5-12-naphthacenedione-pa0445660
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PA 04 45660

(8S-cis)-8-Acetyl-10-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione


  • Catalogue No.:PA 04 45660

  • CAS :

    111248-01-2

  • Molecular Formula : C27H32O8Si

  • Molecular Weight : 512.19

stdClass Object
(
    [pname] => (8S,10S)-10-(((4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(4-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)-4-hydroxy-2-(hydroxymethyl)-1,3-dioxolan-2-yl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
    [catalogue_number] => PA 04 45680
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 1087.05
    [form] => C54H58N2O22
    [cas] => NA
    [pslug] => 8s-10s-10-4s-5s-6s-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl-oxy-8-4-2s-4s-4-2r-4s-5s-6s-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl-oxy-2-5-12-trihydroxy-7-methoxy-6-11-dioxo-1-2-3-4-6-11-hexahydrotetracen-2-yl-4-hydroxy-2-hydroxymethyl-1-3-dioxolan-2-yl-6-8-11-trihydroxy-1-methoxy-7-8-9-10-tetrahydrotetracene-5-12-dione-pa0445680
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PA 04 45680

(8S,10S)-10-(((4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(4-((2S,4S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)-4-hydroxy-2-(hydroxymethyl)-1,3-dioxolan-2-yl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione


  • Catalogue No.:PA 04 45680

  • CAS :

    NA

  • Molecular Formula : C54H58N2O22

  • Molecular Weight : 1087.05

stdClass Object
(
    [pname] => 9,10-Anhydro Doxorubicin
    [catalogue_number] => PA 04 45690
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 525.51
    [form] => C27H27NO10
    [cas] => 80996-23-2
    [pslug] => 80996-23-2-9-10-anhydro-doxorubicin-pa0445690
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PA 04 45690

9,10-Anhydro Doxorubicin


  • Catalogue No.:PA 04 45690

  • CAS :

    80996-23-2

  • Molecular Formula : C27H27NO10

  • Molecular Weight : 525.51

stdClass Object
(
    [pname] => 11-Deoxydoxorubicin
    [catalogue_number] => PA 04 0451000
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 527.53
    [form] => C27H29NO10
    [cas] => 71800-89-0
    [pslug] => 71800-89-0-11-deoxydoxorubicin-pa040451000
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PA 04 0451000

11-Deoxydoxorubicin


  • Catalogue No.:PA 04 0451000

  • CAS :

    71800-89-0

  • Molecular Formula : C27H29NO10

  • Molecular Weight : 527.53

stdClass Object
(
    [pname] => 7-Deoxy Doxorubicin Aglycone
    [catalogue_number] => PA 04 45630
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 398.37
    [form] => C21H18O8
    [cas] => 38554-25-5
    [pslug] => 38554-25-5-7-deoxy-doxorubicin-aglycone-pa0445630
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PA 04 45630

7-Deoxy Doxorubicin Aglycone


  • Catalogue No.:PA 04 45630

  • CAS :

    38554-25-5

  • Molecular Formula : C21H18O8

  • Molecular Weight : 398.37

stdClass Object
(
    [pname] => Doxorubicin Dimer
    [catalogue_number] => PA 31 0761000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 858.85
    [form] => C44H46N2O16
    [cas] => NA
    [pslug] => doxorubicin-dimer-pa310761000
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PA 31 0761000

Doxorubicin Dimer


  • Catalogue No.:PA 31 0761000

  • CAS :

    NA

  • Molecular Formula : C44H46N2O16

  • Molecular Weight : 858.85

stdClass Object
(
    [pname] => 4,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid
    [catalogue_number] => PA 31 0761001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 382.32
    [form] => C20H14O8
    [cas] => NA
    [pslug] => 4-5-12-trihydroxy-7-methoxy-6-11-dioxo-3-4-6-11-tetrahydrotetracene-2-carboxylic-acid-pa310761001
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PA 31 0761001

4,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid


  • Catalogue No.:PA 31 0761001

  • CAS :

    NA

  • Molecular Formula : C20H14O8

  • Molecular Weight : 382.32

stdClass Object
(
    [pname] => 11-Deoxydoxorubicin Hydrochloride
    [catalogue_number] => PA 04 0451001
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 563.98
    [form] => C27H30ClNO10
    [cas] => 73952-94-0
    [pslug] => 73952-94-0-11-deoxydoxorubicin-hydrochloride-pa040451001
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PA 04 0451001

11-Deoxydoxorubicin Hydrochloride


  • Catalogue No.:PA 04 0451001

  • CAS :

    73952-94-0

  • Molecular Formula : C27H30ClNO10

  • Molecular Weight : 563.98

stdClass Object
(
    [pname] => Ethyl 3-(1-ethylpropoxy)benzoate
    [catalogue_number] => PA 31 0761002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 236.31
    [form] => C14H20O3
    [cas] => 1151665-78-9
    [pslug] => 1151665-78-9-ethyl-3-1-ethylpropoxy-benzoate-pa310761002
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PA 31 0761002

Ethyl 3-(1-ethylpropoxy)benzoate


  • Catalogue No.:PA 31 0761002

  • CAS :

    1151665-78-9

  • Molecular Formula : C14H20O3

  • Molecular Weight : 236.31

stdClass Object
(
    [pname] => Doxorubicinol 13CD3 TFA 
    [catalogue_number] => PA STI 089023
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 663.57
    [form] => C2813CH29D3F3NO13
    [cas] => NA
    [pslug] => doxorubicinol-13cd3-tfa -pasti089023
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PA STI 089023

Doxorubicinol 13CD3 TFA 


  • Catalogue No.:PA STI 089023

  • CAS :

    NA

  • Molecular Formula : C2813CH29D3F3NO13

  • Molecular Weight : 663.57

stdClass Object
(
    [pname] => (8S,8'S,10S,10'S)-8,8'-(4-hydroxy-2-(hydroxymethyl)-1,3-dioxolane-2,4-diyl)bis(10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione)
    [catalogue_number] => PA 31 0761004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 1087.05
    [form] => C54H58N2O22
    [cas] => NA
    [pslug] => 8s-8s-10s-10s-8-8-4-hydroxy-2-hydroxymethyl-1-3-dioxolane-2-4-diyl-bis-10-2r-4s-5s-6s-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl-oxy-6-8-11-trihydroxy-1-methoxy-7-8-9-10-tetrahydrotetracene-5-12-dione-pa310761004
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PA 31 0761004

(8S,8'S,10S,10'S)-8,8'-(4-hydroxy-2-(hydroxymethyl)-1,3-dioxolane-2,4-diyl)bis(10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione)


  • Catalogue No.:PA 31 0761004

  • CAS :

    NA

  • Molecular Formula : C54H58N2O22

  • Molecular Weight : 1087.05

stdClass Object
(
    [pname] => (S)-4-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,12-dihydroxy-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid compound with 2,2,2-trifluoroacetic Acid
    [catalogue_number] => PA 31 0761005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 625.51
    [form] => C28H26F3NO12
    [cas] => NA
    [pslug] => s-4-2r-4s-5s-6s-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl-oxy-5-12-dihydroxy-7-methoxy-6-11-dioxo-3-4-6-11-tetrahydrotetracene-2-carboxylic-acid-compound-with-2-2-2-trifluoroacetic-acid-pa310761005
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PA 31 0761005

(S)-4-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,12-dihydroxy-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid compound with 2,2,2-trifluoroacetic Acid


  • Catalogue No.:PA 31 0761005

  • CAS :

    NA

  • Molecular Formula : C28H26F3NO12

  • Molecular Weight : 625.51

stdClass Object
(
    [pname] => Duborimycin
    [catalogue_number] => PA 31 0761006
    [category_ids] => ,71,81,78,82,
    [chemical_name] => 
    [weight] => 529.54
    [form] => C27H31NO10
    [cas] => 28008-55-1
    [pslug] => 28008-55-1-duborimycin-pa310761006
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PA 31 0761006

Duborimycin


  • Catalogue No.:PA 31 0761006

  • CAS :

    28008-55-1

  • Molecular Formula : C27H31NO10

  • Molecular Weight : 529.54