Ezetimibe-Impurities | Pharmaffiliates

ezetimibe

An anti-hyperlipidemic medication, it is used for cholesterol lowering that decreases the absorption of cholesterol in the small intestine. Ezetimibe is hence used for treating high cholesterol. Reference standards of Ezetimibe API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (3'R,3R,4R)-Ezetimibe
    [catalogue_number] => PA 05 41520
    [category_ids] => ,80,71,81,78,70,82,89,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593542-96-1
    [pslug] => 1593542-96-1-3r-3r-4r-ezetimibe-pa0541520
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PA 05 41520

(3'R,3R,4R)-Ezetimibe


  • Catalogue No.:PA 05 41520

  • CAS :

    1593542-96-1

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe (SSR)-Isomer
    [catalogue_number] => PA 05 41570
    [category_ids] => ,75,81,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1593543-00-0
    [pslug] => 1593543-00-0-ezetimibe-ssr-isomer-pa0541570
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PA 05 41570

Ezetimibe (SSR)-Isomer


  • Catalogue No.:PA 05 41570

  • CAS :

    1593543-00-0

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => Ezetimibe Diol Impurity
    [catalogue_number] => PA 05 41590
    [category_ids] => ,80,71,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 413.46
    [form] => C24H25F2NO3
    [cas] => 1374250-08-4
    [pslug] => 1374250-08-4-ezetimibe-diol-impurity-pa0541590
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PA 05 41590

Ezetimibe Diol Impurity


  • Catalogue No.:PA 05 41590

  • CAS :

    1374250-08-4

  • Molecular Formula : C24H25F2NO3

  • Molecular Weight : 413.46

stdClass Object
(
    [pname] => (4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41670
    [category_ids] => ,80,78,70,82,89,79,71,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 272778-12-8
    [pslug] => 272778-12-8-4s3-2r-5s-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-1-oxo-5-trimethylsilyl-oxy-pentyl-4-phenyl-2-oxazolidinone-pa0541670
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PA 05 41670

(4S3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41670

  • CAS :

    272778-12-8

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one
    [catalogue_number] => PA 05 41690
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 389.42
    [form] => C24H20FNO3
    [cas] => 163222-31-9
    [pslug] => 163222-31-9-3r-4s-1-4-fluorophenyl-4-4-hydroxyphenyl-3-3-oxo-3-phenylpropyl-azetidin-2-one-pa0541690
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PA 05 41690

(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one


  • Catalogue No.:PA 05 41690

  • CAS :

    163222-31-9

  • Molecular Formula : C24H20FNO3

  • Molecular Weight : 389.42

stdClass Object
(
    [pname] => Mixture of (Ezetimibe Keto Isomer, Ezetimibe Keto And Ezetimibe) 
    [catalogue_number] => PA 05 41700
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 1224.24
    [form] => C72H59F6N3O9
    [cas] => NA
    [pslug] => mixture-of-ezetimibe-keto-isomer-ezetimibe-keto-and-ezetimibe-pa0541700
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PA 05 41700

Mixture of (Ezetimibe Keto Isomer, Ezetimibe Keto And Ezetimibe)


  • Catalogue No.:PA 05 41700

  • CAS :

    NA

  • Molecular Formula : C72H59F6N3O9

  • Molecular Weight : 1224.24

stdClass Object
(
    [pname] => Mixture of (Ezetimibe and Ezetimibe (RRS)-Isomer)
    [catalogue_number] => PA 05 41710
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 818.85
    [form] => C48H42F4N2O6
    [cas] => NA
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PA 05 41710

Mixture of (Ezetimibe and Ezetimibe (RRS)-Isomer)


  • Catalogue No.:PA 05 41710

  • CAS :

    NA

  • Molecular Formula : C48H42F4N2O6

  • Molecular Weight : 818.85

stdClass Object
(
    [pname] => Mixture of (Des-F Ezetimibe-15 And Ezetimibe-15)
    [catalogue_number] => PA 05 41720
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 692.73
    [form] => C40H37FN2O8
    [cas] => NA
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PA 05 41720

Mixture of (Des-F Ezetimibe-15 And Ezetimibe-15)


  • Catalogue No.:PA 05 41720

  • CAS :

    NA

  • Molecular Formula : C40H37FN2O8

  • Molecular Weight : 692.73

stdClass Object
(
    [pname] => Mixture of (Des-fluoro-A Ezetimibe And Des-fluoro-B Ezetimibe)
    [catalogue_number] => PA 05 41730
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 1192.29
    [form] => C72H65F4N3O9
    [cas] => NA
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PA 05 41730

Mixture of (Des-fluoro-A Ezetimibe And Des-fluoro-B Ezetimibe)


  • Catalogue No.:PA 05 41730

  • CAS :

    NA

  • Molecular Formula : C72H65F4N3O9

  • Molecular Weight : 1192.29

stdClass Object
(
    [pname] => Mixtuure of (Ezetimibe Acid And Ezetimibe RRS Acid)
    [catalogue_number] => PA 05 41740
    [category_ids] => ,80,78,70,82,89,79,
    [chemical_name] => 
    [weight] => 866.75
    [form] => C48H44F4Li2N2O8
    [cas] => NA
    [pslug] => mixtuure-of-ezetimibe-acid-and-ezetimibe-rrs-acid-pa0541740
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PA 05 41740

Mixtuure of (Ezetimibe Acid And Ezetimibe RRS Acid)


  • Catalogue No.:PA 05 41740

  • CAS :

    NA

  • Molecular Formula : C48H44F4Li2N2O8

  • Molecular Weight : 866.75

stdClass Object
(
    [pname] => 4-{(E)-[(3-Fluorophenyl)imino]methyl}phenol
    [catalogue_number] => PA 05 41750
    [category_ids] => ,80,75,78,70,82,89,
    [chemical_name] => 
    [weight] => 215.22
    [form] => C13H10FNO
    [cas] => 1829558-53-3
    [pslug] => 1829558-53-3-4-e-3-fluorophenyl-imino-methyl-phenol-pa0541750
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PA 05 41750

4-{(E)-[(3-Fluorophenyl)imino]methyl}phenol


  • Catalogue No.:PA 05 41750

  • CAS :

    1829558-53-3

  • Molecular Formula : C13H10FNO

  • Molecular Weight : 215.22

stdClass Object
(
    [pname] => 4-{(E)-[(2-fluorophenyl)imino]methyl}phenol
    [catalogue_number] => PA 05 41760
    [category_ids] => ,80,75,78,70,82,89,
    [chemical_name] => 
    [weight] => 215.22
    [form] => C13H10FNO
    [cas] => 1829558-56-6
    [pslug] => 1829558-56-6-4-e-2-fluorophenyl-imino-methyl-phenol-pa0541760
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PA 05 41760

4-{(E)-[(2-fluorophenyl)imino]methyl}phenol


  • Catalogue No.:PA 05 41760

  • CAS :

    1829558-56-6

  • Molecular Formula : C13H10FNO

  • Molecular Weight : 215.22

stdClass Object
(
    [pname] => ((4R)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one)
    [catalogue_number] => PA 05 41820
    [category_ids] => ,80,78,70,82,89,92,
    [chemical_name] => 
    [weight] => 357.38
    [form] => C20H20FNO4
    [cas] => 404874-94-8
    [pslug] => 404874-94-8-4r-3-5s-5-4-fluorophenyl-5-hydroxypentanoyl-4-phenyl-1-3-oxazolidin-2-one-pa0541820
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PA 05 41820

((4R)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one)


  • Catalogue No.:PA 05 41820

  • CAS :

    404874-94-8

  • Molecular Formula : C20H20FNO4

  • Molecular Weight : 357.38

stdClass Object
(
    [pname] => Ezetimibe Benzyl Impurity
    [catalogue_number] => PA 05 41840
    [category_ids] => 80,89,92
    [chemical_name] => 
    [weight] => 499.56
    [form] => C31H27F2NO3
    [cas] => 851860-29-2
    [pslug] => 851860-29-2-ezetimibe-benzyl-impurity-pa0541840
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PA 05 41840

Ezetimibe Benzyl Impurity


  • Catalogue No.:PA 05 41840

  • CAS :

    851860-29-2

  • Molecular Formula : C31H27F2NO3

  • Molecular Weight : 499.56

stdClass Object
(
    [pname] => Ezetimibe Open-Ring Anhydro Alcohol
    [catalogue_number] => PA 05 41850
    [category_ids] => ,80,89,92,
    [chemical_name] => 
    [weight] => 395.44
    [form] => C24H23F2NO2
    [cas] => 1374250-07-3
    [pslug] => 1374250-07-3-ezetimibe-open-ring-anhydro-alcohol-pa0541850
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PA 05 41850

Ezetimibe Open-Ring Anhydro Alcohol


  • Catalogue No.:PA 05 41850

  • CAS :

    1374250-07-3

  • Molecular Formula : C24H23F2NO2

  • Molecular Weight : 395.44

stdClass Object
(
    [pname] => Ezetimibe Ring-opening Dehydrate Impurity
    [catalogue_number] => PA 05 41860
    [category_ids] => ,80,89,92,
    [chemical_name] => 
    [weight] => 409.43
    [form] => C24H21F2NO3
    [cas] => 1292292-63-7
    [pslug] => 1292292-63-7-ezetimibe-ring-opening-dehydrate-impurity-pa0541860
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PA 05 41860

Ezetimibe Ring-opening Dehydrate Impurity


  • Catalogue No.:PA 05 41860

  • CAS :

    1292292-63-7

  • Molecular Formula : C24H21F2NO3

  • Molecular Weight : 409.43

stdClass Object
(
    [pname] => (R)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
    [catalogue_number] => PA 05 41870
    [category_ids] => ,80,89,92,
    [chemical_name] => 
    [weight] => 355.35
    [form] => C20H18FNO4
    [cas] => 404874-93-7
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PA 05 41870

(R)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione


  • Catalogue No.:PA 05 41870

  • CAS :

    404874-93-7

  • Molecular Formula : C20H18FNO4

  • Molecular Weight : 355.35

stdClass Object
(
    [pname] => (S)-1-(3-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
    [catalogue_number] => PA 05 41880
    [category_ids] => ,80,89,92,
    [chemical_name] => 
    [weight] => 355.36
    [form] => C20H18FNO4
    [cas] => 2514696-40-1
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PA 05 41880

(S)-1-(3-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione


  • Catalogue No.:PA 05 41880

  • CAS :

    2514696-40-1

  • Molecular Formula : C20H18FNO4

  • Molecular Weight : 355.36

stdClass Object
(
    [pname] => (S)-3-((S)-5-(4-Fluorophenyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41930
    [category_ids] => ,89,80,79,92,
    [chemical_name] => 
    [weight] => 429.56
    [form] => C23H28FNO4Si
    [cas] => 1354716-94-1
    [pslug] => 1354716-94-1-s-3-s-5-4-fluorophenyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541930
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PA 05 41930

(S)-3-((S)-5-(4-Fluorophenyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41930

  • CAS :

    1354716-94-1

  • Molecular Formula : C23H28FNO4Si

  • Molecular Weight : 429.56

stdClass Object
(
    [pname] => (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41940
    [category_ids] => ,78,70,82,71,89,80,79,
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    [weight] => 644.78
    [form] => C36H38F2N2O5Si
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PA 05 41940

(S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41940

  • CAS :

    NA

  • Molecular Formula : C36H38F2N2O5Si

  • Molecular Weight : 644.78

stdClass Object
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    [pname] => (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
    [catalogue_number] => PA 05 41950
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => NA
    [pslug] => 4s-3-2r-5s-5-4-fluorophenyl-2-r-3-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-1-oxo-5-trimethylsilyl-oxy-pentyl-4-phenyl-2-oxazolidinone-pa0541950
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PA 05 41950

(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(R)-[(3-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone


  • Catalogue No.:PA 05 41950

  • CAS :

    NA

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
(
    [pname] => (S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one
    [catalogue_number] => PA 05 41960
    [category_ids] => ,78,70,82,71,89,80,79,
    [chemical_name] => 
    [weight] => 716.96
    [form] => C39H46F2N2O5Si2
    [cas] => 1809031-15-9
    [pslug] => 1809031-15-9-s-3-2r-5r-5-4-fluorophenyl-2-s-4-fluorophenyl-amino-4-trimethylsilyl-oxy-phenyl-methyl-5-trimethylsilyl-oxy-pentanoyl-4-phenyloxazolidin-2-one-pa0541960
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PA 05 41960

(S)-3-((2R,5R)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one


  • Catalogue No.:PA 05 41960

  • CAS :

    1809031-15-9

  • Molecular Formula : C39H46F2N2O5Si2

  • Molecular Weight : 716.96

stdClass Object
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    [pname] => Ezetimibe Triol Impurity
    [catalogue_number] => PA 05 41970
    [category_ids] => ,78,70,82,71,89,80,
    [chemical_name] => 
    [weight] => 572.61
    [form] => C33H30F2N2O5
    [cas] => 2363086-22-8
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PA 05 41970

Ezetimibe Triol Impurity


  • Catalogue No.:PA 05 41970

  • CAS :

    2363086-22-8

  • Molecular Formula : C33H30F2N2O5

  • Molecular Weight : 572.61

stdClass Object
(
    [pname] => (3R,4S)-1-(3-Fluorophenyl)-3-(3-(4-fluorophenyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one
    [catalogue_number] => PA 05 41515
    [category_ids] => ,89,80,79,92,
    [chemical_name] => 
    [weight] => 393.43
    [form] => C24H21F2NO2
    [cas] => NA
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PA 05 41515

(3R,4S)-1-(3-Fluorophenyl)-3-(3-(4-fluorophenyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one


  • Catalogue No.:PA 05 41515

  • CAS :

    NA

  • Molecular Formula : C24H21F2NO2

  • Molecular Weight : 393.43