Ticagrelor-impurities | Pharmaffiliates

ticagrelor

A P2Y12 receptor antagonist drug, used as a platelet aggregation inhibitor. Ticagrelor is a nucleoside analogue used in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases. Reference standards of Ticagrelor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate
    [catalogue_number] => PA 47 11525
    [category_ids] => ,79,80,69,70,92,89,
    [chemical_name] => 
    [weight] => 226.22
    [form] => C12H12F2O2
    [cas] => NA
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PA 47 11525

Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate


  • Catalogue No.:PA 47 11525

  • CAS :

    NA

  • Molecular Formula : C12H12F2O2

  • Molecular Weight : 226.22

stdClass Object
(
    [pname] => (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid
    [catalogue_number] => PA 47 11580
    [category_ids] => ,79,80,78,70,82,92,89,
    [chemical_name] => 
    [weight] => 198.17
    [form] => C10H8F2O2
    [cas] => 220352-36-3
    [pslug] => 220352-36-3-1r-2r-2-3-4-difluorophenyl-cyclopropanecarboxylic-acid-pa4711580
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PA 47 11580

(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid


  • Catalogue No.:PA 47 11580

  • CAS :

    220352-36-3

  • Molecular Formula : C10H8F2O2

  • Molecular Weight : 198.17

stdClass Object
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    [pname] => (1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11585
    [category_ids] => 92,89,82,80,79,78,70
    [chemical_name] => 
    [weight] => 522.57
    [form] => C23H28F2N6O4S
    [cas] => 2056269-94-2
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PA 47 11585

(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11585

  • CAS :

    2056269-94-2

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

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    [pname] => (1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11595
    [category_ids] => ,79,80,78,70,82,89,
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    [weight] => 522.57
    [form] => C23H28F2N6O4S
    [cas] => NA
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PA 47 11595

(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11595

  • CAS :

    NA

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

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(
    [pname] => (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
    [catalogue_number] => PA 47 11620
    [category_ids] => ,80,79,89,88,
    [chemical_name] => 
    [weight] => 389.86
    [form] => C14H20ClN5O4S
    [cas] => 1354945-69-9
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PA 47 11620

(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol


  • Catalogue No.:PA 47 11620

  • CAS :

    1354945-69-9

  • Molecular Formula : C14H20ClN5O4S

  • Molecular Weight : 389.86

stdClass Object
(
    [pname] => 2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo [4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethyl Hydrogen Sulfate
    [catalogue_number] => PA 47 11630
    [category_ids] => ,80,79,89,88,71,
    [chemical_name] => 
    [weight] => 602.63
    [form] => C23H28F2N6O7S2
    [cas] => NA
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PA 47 11630

2-(((1S,2S,3S,4R)-4-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo [4,5-d]pyrimidin-3-yl)-2,3-dihydroxycyclopentyl)oxy)ethyl Hydrogen Sulfate


  • Catalogue No.:PA 47 11630

  • CAS :

    NA

  • Molecular Formula : C23H28F2N6O7S2

  • Molecular Weight : 602.63

stdClass Object
(
    [pname] => (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(2,3-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
    [catalogue_number] => PA 47 11640
    [category_ids] => ,80,79,89,88,71,
    [chemical_name] => 
    [weight] => 522.57
    [form] => C23H28F2N6O4S
    [cas] => 1643378-48-6
    [pslug] => 1643378-48-6-1s-2s-3r-5s-3-7-1r-2s-2-2-3-difluorophenyl-cyclopropyl-amino-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-5-2-hydroxyethoxy-1-2-cyclopentanediol-pa4711640
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PA 47 11640

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(2,3-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol


  • Catalogue No.:PA 47 11640

  • CAS :

    1643378-48-6

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

stdClass Object
(
    [pname] => (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(4-Fluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
    [catalogue_number] => PA 47 11650
    [category_ids] => ,80,79,89,88,71,
    [chemical_name] => 
    [weight] => 504.58
    [form] => C23H29FN6O4S
    [cas] => 1643378-47-5
    [pslug] => 1643378-47-5-1s-2s-3r-5s-3-7-1r-2s-2-4-fluorophenyl-cyclopropyl-amino-5-propylthio-3h-1-2-3-triazolo-4-5-d-pyrimidin-3-yl-5-2-hydroxyethoxy-1-2-cyclopentanediol-pa4711650
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PA 47 11650

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(4-Fluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol


  • Catalogue No.:PA 47 11650

  • CAS :

    1643378-47-5

  • Molecular Formula : C23H29FN6O4S

  • Molecular Weight : 504.58

stdClass Object
(
    [pname] => ent-Ticagrelor
    [catalogue_number] => PA 47 11670
    [category_ids] => ,80,79,89,88,71,
    [chemical_name] => 
    [weight] => 522.57
    [form] => C23H28F2N6O4S
    [cas] => 2096989-55-6
    [pslug] => 2096989-55-6-ent-ticagrelor-pa4711670
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PA 47 11670

ent-Ticagrelor


  • Catalogue No.:PA 47 11670

  • CAS :

    2096989-55-6

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

stdClass Object
(
    [pname] => (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
    [catalogue_number] => PA 47 11680
    [category_ids] => ,80,79,89,71,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => NA
    [pslug] => 1r-2r-2-3-4-difluorophenyl-cyclopropanamine-hydrochloride-pa4711680
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PA 47 11680

(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride


  • Catalogue No.:PA 47 11680

  • CAS :

    NA

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

stdClass Object
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    [pname] => (1S,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
    [catalogue_number] => PA 47 11690
    [category_ids] => ,80,79,89,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
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PA 47 11690

(1S,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride


  • Catalogue No.:PA 47 11690

  • CAS :

    NA

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

stdClass Object
(
    [pname] => (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide
    [catalogue_number] => PA 47 11700
    [category_ids] => ,80,79,89,
    [chemical_name] => 
    [weight] => 197.18
    [form] => C10H9F2NO
    [cas] => 1006376-62-0
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PA 47 11700

(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide


  • Catalogue No.:PA 47 11700

  • CAS :

    1006376-62-0

  • Molecular Formula : C10H9F2NO

  • Molecular Weight : 197.18

stdClass Object
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    [pname] => (1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11800
    [category_ids] => ,80,71,76,75,78,70,82,88,89,
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    [weight] => 522.57
    [form] => C23H28F2N6O4S
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PA 47 11800

(1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11800

  • CAS :

    2096989-56-7

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

stdClass Object
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    [pname] => (1R,2S)-2-(3-Fluorophenyl)cyclopropanamine
    [catalogue_number] => PA 47 11820
    [category_ids] => ,80,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 151.18
    [form] => C9H10FN
    [cas] => 220353-83-3
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PA 47 11820

(1R,2S)-2-(3-Fluorophenyl)cyclopropanamine


  • Catalogue No.:PA 47 11820

  • CAS :

    220353-83-3

  • Molecular Formula : C9H10FN

  • Molecular Weight : 151.18

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    [pname] => (1R,2S)-2-(4-Fluorophenyl)cyclopropanamine
    [catalogue_number] => PA 47 11830
    [category_ids] => ,80,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 151.18
    [form] => C9H10FN
    [cas] => 220349-80-4
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PA 47 11830

(1R,2S)-2-(4-Fluorophenyl)cyclopropanamine


  • Catalogue No.:PA 47 11830

  • CAS :

    220349-80-4

  • Molecular Formula : C9H10FN

  • Molecular Weight : 151.18

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    [pname] => 4,6-Dichloro-2-propylthiopyrimidine-5-amine
    [catalogue_number] => PA 47 11840
    [category_ids] => ,80,78,70,82,79,89,79,88,
    [chemical_name] => 
    [weight] => 238.14
    [form] => C7H9Cl2N3S
    [cas] => 145783-15-9
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PA 47 11840

4,6-Dichloro-2-propylthiopyrimidine-5-amine


  • Catalogue No.:PA 47 11840

  • CAS :

    145783-15-9

  • Molecular Formula : C7H9Cl2N3S

  • Molecular Weight : 238.14

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    [pname] => (1R,2R,3S,5R)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11605
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    [weight] => 522.57
    [form] => C23H28F2N6O4S
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PA 47 11605

(1R,2R,3S,5R)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11605

  • CAS :

    NA

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

stdClass Object
(
    [pname] => 2-(((3aR,4S,6S,6aS)-6-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 47 11655
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    [weight] => 576.66
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PA 47 11655

2-(((3aR,4S,6S,6aS)-6-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol


  • Catalogue No.:PA 47 11655

  • CAS :

    NA

  • Molecular Formula : C27H34F2N6O4S

  • Molecular Weight : 576.66

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    [pname] => (1S,2S,3S,5S)-3-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11665
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PA 47 11665

(1S,2S,3S,5S)-3-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11665

  • CAS :

    NA

  • Molecular Formula : C23H28F2N6O4S

  • Molecular Weight : 522.57

stdClass Object
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    [pname] => 2-(((3aR,4S,6R,6aS)-6-(5-(Butylthio)-7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
    [catalogue_number] => PA 47 11675
    [category_ids] => ,80,89,78,70,82,88,
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PA 47 11675

2-(((3aR,4S,6R,6aS)-6-(5-(Butylthio)-7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol


  • Catalogue No.:PA 47 11675

  • CAS :

    NA

  • Molecular Formula : C27H34F2N6O4S

  • Molecular Weight : 576.66

stdClass Object
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    [pname] => (1S,2S,3R,5S)-3-(5-(Butylthio)-7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11685
    [category_ids] => ,80,89,78,70,82,88,
    [chemical_name] => 
    [weight] => 536.6
    [form] => C24H30F2N6O4S
    [cas] => NA
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PA 47 11685

(1S,2S,3R,5S)-3-(5-(Butylthio)-7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11685

  • CAS :

    NA

  • Molecular Formula : C24H30F2N6O4S

  • Molecular Weight : 536.6

stdClass Object
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    [pname] => (1S,2S,3R,5S)-3-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
    [catalogue_number] => PA 47 11695
    [category_ids] => ,80,89,78,70,82,88,
    [chemical_name] => 
    [weight] => 536.6
    [form] => C24H30F2N6O4S
    [cas] => NA
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PA 47 11695

(1S,2S,3R,5S)-3-(5-(Butylthio)-7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


  • Catalogue No.:PA 47 11695

  • CAS :

    NA

  • Molecular Formula : C24H30F2N6O4S

  • Molecular Weight : 536.6

stdClass Object
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    [pname] => N-Hydroxy Ticagrelor
    [catalogue_number] => PA 47 11715
    [category_ids] => ,80,89,78,70,82,88,
    [chemical_name] => 
    [weight] => 538.57
    [form] => C23H28F2N6O5S
    [cas] => 1644461-92-6
    [pslug] => 1644461-92-6-n-hydroxy-ticagrelor-pa4711715
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PA 47 11715

N-Hydroxy Ticagrelor


  • Catalogue No.:PA 47 11715

  • CAS :

    1644461-92-6

  • Molecular Formula : C23H28F2N6O5S

  • Molecular Weight : 538.57

stdClass Object
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    [pname] => (2S,3S)-2-((5-(Butylthio)-3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3-(3,4-difluorophenyl)cyclopropan-1-one
    [catalogue_number] => PA 47 11725
    [category_ids] => ,80,89,78,70,82,88,
    [chemical_name] => 
    [weight] => 550.58
    [form] => C24H28F2N6O5S
    [cas] => NA
    [pslug] => 2s-3s-2-5-butylthio-3-1r-2s-3s-4s-2-3-dihydroxy-4-2-hydroxyethoxy-cyclopentyl-3h-1-2-3-triazolo-4-5-d-pyrimidin-7-yl-amino-3-3-4-difluorophenyl-cyclopropan-1-one-pa4711725
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PA 47 11725

(2S,3S)-2-((5-(Butylthio)-3-((1R,2S,3S,4S)-2,3-dihydroxy-4-(2-hydroxyethoxy)cyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3-(3,4-difluorophenyl)cyclopropan-1-one


  • Catalogue No.:PA 47 11725

  • CAS :

    NA

  • Molecular Formula : C24H28F2N6O5S

  • Molecular Weight : 550.58

stdClass Object
(
    [pname] => 6-Chloro-N4-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-2-(propylthio)pyrimidine-4,5-diamine
    [catalogue_number] => PA 47 11735
    [category_ids] => ,80,89,78,70,82,88,
    [chemical_name] => 
    [weight] => 370.85
    [form] => C16H17ClF2N4S
    [cas] => NA
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PA 47 11735

6-Chloro-N4-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-2-(propylthio)pyrimidine-4,5-diamine


  • Catalogue No.:PA 47 11735

  • CAS :

    NA

  • Molecular Formula : C16H17ClF2N4S

  • Molecular Weight : 370.85

stdClass Object
(
    [pname] => (1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine
    [catalogue_number] => PA 47 11805
    [category_ids] => ,80,89,78,70,82,
    [chemical_name] => 
    [weight] => 169.17
    [form] => C9H9F2N
    [cas] => 1459719-81-3
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PA 47 11805

(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine


  • Catalogue No.:PA 47 11805

  • CAS :

    1459719-81-3

  • Molecular Formula : C9H9F2N

  • Molecular Weight : 169.17

stdClass Object
(
    [pname] => Ticagrelor - Impurity E (Hydrochloride Salt)
    [catalogue_number] => PA 47 0110051
    [category_ids] => ,79,80,89,
    [chemical_name] => 
    [weight] => 205.63
    [form] => C9H10ClF2N
    [cas] => 1402222-66-5
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PA 47 0110051

Ticagrelor - Impurity E (Hydrochloride Salt)


  • Catalogue No.:PA 47 0110051

  • CAS :

    1402222-66-5

  • Molecular Formula : C9H10ClF2N

  • Molecular Weight : 205.63

stdClass Object
(
    [pname] => rel-(1R,2S)-2-(4-Fluorophenyl)cyclopropan-1-amine
    [catalogue_number] => PA 47 0111110
    [category_ids] => ,80,78,70,82,79,89,
    [chemical_name] => 
    [weight] => 151.18
    [form] => C9H10FN
    [cas] => 113516-71-5
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PA 47 0111110

rel-(1R,2S)-2-(4-Fluorophenyl)cyclopropan-1-amine


  • Catalogue No.:PA 47 0111110

  • CAS :

    113516-71-5

  • Molecular Formula : C9H10FN

  • Molecular Weight : 151.18