Dasatinib-impurities | Pharmaffiliates

dasatinib

A Bcr-Abl tyrosine kinase inhibitor, Dasatinib is an anti cancer drug. It is administered orally and used for the treatment of prostrate cancer and many other cancers. It is a Src family tyrosine kinase inhibitor used for treating leukemia.. Reference standards of Dasatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => N-Boc-N-deshydroxyethyl Dasatinib
    [catalogue_number] => PA 04 07510
    [category_ids] => 88,80,71,70,78,82
    [chemical_name] => 
    [weight] => 544.07
    [form] => C25H30ClN7O3S
    [cas] => 1159977-13-5
    [pslug] => 1159977-13-5-n-boc-n-deshydroxyethyl-dasatinib-pa0407510
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PA 04 07510

N-Boc-N-deshydroxyethyl Dasatinib


  • Catalogue No.:PA 04 07510

  • CAS :

    1159977-13-5

  • Molecular Formula : C25H30ClN7O3S

  • Molecular Weight : 544.07

stdClass Object
(
    [pname] => N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[(triphenylmethyl)amino]-5-thiazolecarboxamide
    [catalogue_number] => PA 04 07540
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 526.05
    [form] => C30H24ClN3O2S
    [cas] => 910297-68-6
    [pslug] => 910297-68-6-n-2-chloro-6-hydroxymethyl-phenyl-2-triphenylmethyl-amino-5-thiazolecarboxamide-pa0407540
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PA 04 07540

N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[(triphenylmethyl)amino]-5-thiazolecarboxamide


  • Catalogue No.:PA 04 07540

  • CAS :

    910297-68-6

  • Molecular Formula : C30H24ClN3O2S

  • Molecular Weight : 526.05

stdClass Object
(
    [pname] => N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
    [catalogue_number] => PA 04 07550
    [category_ids] => 88,82,78,71,70
    [chemical_name] => 
    [weight] => 394.28
    [form] => C16H13Cl2N5OS
    [cas] => 302964-08-5
    [pslug] => 302964-08-5-n-2-chloro-6-methylphenyl-2-6-chloro-2-methyl-4-pyrimidinyl-amino-5-thiazolecarboxamide-pa0407550
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PA 04 07550

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide


  • Catalogue No.:PA 04 07550

  • CAS :

    302964-08-5

  • Molecular Formula : C16H13Cl2N5OS

  • Molecular Weight : 394.28

stdClass Object
(
    [pname] => Dasatinib Carboxylic Acid
    [catalogue_number] => PA 04 07560
    [category_ids] => 88,76,75,70,71,78,82
    [chemical_name] => 
    [weight] => 501.99
    [form] => C22H24ClN7O3S
    [cas] => 910297-53-9
    [pslug] => 910297-53-9-dasatinib-carboxylic-acid-pa0407560
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PA 04 07560

Dasatinib Carboxylic Acid


  • Catalogue No.:PA 04 07560

  • CAS :

    910297-53-9

  • Molecular Formula : C22H24ClN7O3S

  • Molecular Weight : 501.99

stdClass Object
(
    [pname] => Dasatinib Carboxylic Acid Ethyl Ester
    [catalogue_number] => PA 04 07580
    [category_ids] => ,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 530.04
    [form] => C24H28ClN7O3S
    [cas] => 910297-62-0
    [pslug] => 910297-62-0-dasatinib-carboxylic-acid-ethyl-ester-pa0407580
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PA 04 07580

Dasatinib Carboxylic Acid Ethyl Ester


  • Catalogue No.:PA 04 07580

  • CAS :

    910297-62-0

  • Molecular Formula : C24H28ClN7O3S

  • Molecular Weight : 530.04

stdClass Object
(
    [pname] => Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib
    [catalogue_number] => PA 04 07630
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 494.39
    [form] => C21H21Cl2N5O3S
    [cas] => 910297-70-0
    [pslug] => 910297-70-0-des-6-4-2-hydroxyethyl-1-piperazinyl-6-chloro-o-pivalate-dasatinib-pa0407630
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PA 04 07630

Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib


  • Catalogue No.:PA 04 07630

  • CAS :

    910297-70-0

  • Molecular Formula : C21H21Cl2N5O3S

  • Molecular Weight : 494.39

stdClass Object
(
    [pname] => 2,2-Dimethyl-propanoic Acid [2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methyl Ester
    [catalogue_number] => PA 04 07640
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 367.85
    [form] => C16H18ClN3O3S
    [cas] => 910297-69-7
    [pslug] => 910297-69-7-2-2-dimethyl-propanoic-acid-2-2-amino-5-thiazolyl-carbonyl-amino-3-chlorophenyl-methyl-ester-pa0407640
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PA 04 07640

2,2-Dimethyl-propanoic Acid [2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methyl Ester


  • Catalogue No.:PA 04 07640

  • CAS :

    910297-69-7

  • Molecular Formula : C16H18ClN3O3S

  • Molecular Weight : 367.85

stdClass Object
(
    [pname] => 2,2-Dimethyl-propanoic Acid [3-Chloro-2-[[[2-[(triphenylmethyl)amino]-5-thiazolyl]carbonyl]amino]phenyl]methyl Ester
    [catalogue_number] => PA 04 07650
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 610.16
    [form] => C35H32ClN3O3S
    [cas] => 910298-41-8
    [pslug] => 910298-41-8-2-2-dimethyl-propanoic-acid-3-chloro-2-2-triphenylmethyl-amino-5-thiazolyl-carbonyl-amino-phenyl-methyl-ester-pa0407650
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PA 04 07650

2,2-Dimethyl-propanoic Acid [3-Chloro-2-[[[2-[(triphenylmethyl)amino]-5-thiazolyl]carbonyl]amino]phenyl]methyl Ester


  • Catalogue No.:PA 04 07650

  • CAS :

    910298-41-8

  • Molecular Formula : C35H32ClN3O3S

  • Molecular Weight : 610.16

stdClass Object
(
    [pname] => 4'-Hydroxy Dasatinib
    [catalogue_number] => PA 04 07660
    [category_ids] => ,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 504
    [form] => C22H26ClN7O3S
    [cas] => 910297-57-3
    [pslug] => 910297-57-3-4-hydroxy-dasatinib-pa0407660
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PA 04 07660

4'-Hydroxy Dasatinib


  • Catalogue No.:PA 04 07660

  • CAS :

    910297-57-3

  • Molecular Formula : C22H26ClN7O3S

  • Molecular Weight : 504

stdClass Object
(
    [pname] => Hydroxymethyl Dasatinib
    [catalogue_number] => PA 04 07670
    [category_ids] => ,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 504
    [form] => C22H26ClN7O3S
    [cas] => 910297-58-4
    [pslug] => 910297-58-4-hydroxymethyl-dasatinib-pa0407670
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PA 04 07670

Hydroxymethyl Dasatinib


  • Catalogue No.:PA 04 07670

  • CAS :

    910297-58-4

  • Molecular Formula : C22H26ClN7O3S

  • Molecular Weight : 504

stdClass Object
(
    [pname] => 2-Amino-N-(2,3-dichloro-6-methylphenyl)thiazole-5-carboxamide
    [catalogue_number] => PA 04 07680
    [category_ids] => ,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 302.18
    [form] => C11H9Cl2N3OS
    [cas] => 2468737-78-0
    [pslug] => 2468737-78-0-2-amino-n-2-3-dichloro-6-methylphenyl-thiazole-5-carboxamide-pa0407680
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PA 04 07680

2-Amino-N-(2,3-dichloro-6-methylphenyl)thiazole-5-carboxamide


  • Catalogue No.:PA 04 07680

  • CAS :

    2468737-78-0

  • Molecular Formula : C11H9Cl2N3OS

  • Molecular Weight : 302.18

stdClass Object
(
    [pname] => 2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic Acid
    [catalogue_number] => PA 04 07740
    [category_ids] => ,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 244.27
    [form] => C9H12N2O4S
    [cas] => 302964-02-9
    [pslug] => 302964-02-9-2-tert-butoxycarbonylamino-thiazole-5-carboxylic-acid-pa0407740
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PA 04 07740

2-(tert-Butoxycarbonylamino)thiazole-5-carboxylic Acid


  • Catalogue No.:PA 04 07740

  • CAS :

    302964-02-9

  • Molecular Formula : C9H12N2O4S

  • Molecular Weight : 244.27

stdClass Object
(
    [pname] => N-Boc-N-deshydroxyethyl Dasatinib-d8
    [catalogue_number] => PA STI 013920
    [category_ids] => ,80,71,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 552.12
    [form] => C25H22D8ClN7O3S
    [cas] => 1263379-04-9
    [pslug] => 1263379-04-9-n-boc-n-deshydroxyethyl-dasatinib-d8-pasti013920
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PA STI 013920

N-Boc-N-deshydroxyethyl Dasatinib-d8


  • Catalogue No.:PA STI 013920

  • CAS :

    1263379-04-9

  • Molecular Formula : C25H22D8ClN7O3S

  • Molecular Weight : 552.12

stdClass Object
(
    [pname] => Dasatinib Acetyl Impurity
    [catalogue_number] => PA 04 07790
    [category_ids] => ,80,71,85,83,78,70,82,
    [chemical_name] => 
    [weight] => 309.77
    [form] => C13H12ClN3O2S
    [cas] => 2518438-16-7
    [pslug] => 2518438-16-7-dasatinib-acetyl-impurity-pa0407790
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PA 04 07790

Dasatinib Acetyl Impurity


  • Catalogue No.:PA 04 07790

  • CAS :

    2518438-16-7

  • Molecular Formula : C13H12ClN3O2S

  • Molecular Weight : 309.77