etoricoxib
A COX-2 inhibitor, Etoricoxib is used in the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, spondylitis, chronic low back pain, and gout. It is a selective inhibitor of isoform 2 of the enzyme cyclooxygenase. Reference standards of Etoricoxib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => 6'-Desmethyl-6'-methylhydroxy Etoricoxib
[catalogue_number] => PA 05 40560
[category_ids] => ,79,80,71,76,75,78,70,82,88,
[chemical_name] =>
[weight] => 374.84
[form] => C18H15ClN2O3S
[cas] => 349536-41-0
[pslug] => 349536-41-0-6-desmethyl-6-methylhydroxy-etoricoxib-pa0540560
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6'-Desmethyl-6'-methylhydroxy Etoricoxib
Catalogue No.:PA 05 40560
Molecular Formula : C18H15ClN2O3S
Molecular Weight : 374.84
stdClass Object
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[pname] => 4-(Methylsulfonyl)phenylacetic Acid
[catalogue_number] => PA 05 40580
[category_ids] => ,79,80,71,78,70,82,88,
[chemical_name] =>
[weight] => 214.24
[form] => C9H10O4S
[cas] => 90536-66-6
[pslug] => 90536-66-6-4-methylsulfonyl-phenylacetic-acid-pa0540580
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4-(Methylsulfonyl)phenylacetic Acid
Catalogue No.:PA 05 40580
Molecular Formula : C9H10O4S
Molecular Weight : 214.24
stdClass Object
(
[pname] => 6'-Desmethyl-6'-carboxy Etoricoxib
[catalogue_number] => PA 05 40590
[category_ids] => ,79,80,71,76,75,78,70,82,88,
[chemical_name] =>
[weight] => 388.82
[form] => C18H13ClN2O4S
[cas] => 349536-39-6
[pslug] => 349536-39-6-6-desmethyl-6-carboxy-etoricoxib-pa0540590
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6'-Desmethyl-6'-carboxy Etoricoxib
Catalogue No.:PA 05 40590
Molecular Formula : C18H13ClN2O4S
Molecular Weight : 388.82
stdClass Object
(
[pname] => Etoricoxib N1'-Oxide
[catalogue_number] => PA 05 40600
[category_ids] => ,80,71,75,78,70,82,88,
[chemical_name] =>
[weight] => 374.84
[form] => C18H15ClN2O3S
[cas] => 325855-74-1
[pslug] => 325855-74-1-etoricoxib-n1-oxide-pa0540600
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Catalogue No.:PA 05 40600
Molecular Formula : C18H15ClN2O3S
Molecular Weight : 374.84