Rapamycin-impurities | Pharmaffiliates

rapamycin

Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2.Reference standards of Rapamycin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Rapamycin - API Standards 
    [catalogue_number] => PA 18 26000
    [category_ids] => 82,81,78,71,70,69
    [chemical_name] => 
    [weight] => 914.17
    [form] => C51H79NO13
    [cas] => 53123-88-9
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PA 18 26000

Rapamycin - API Standards


  • Catalogue No.:PA 18 26000

  • CAS :

    53123-88-9

  • Molecular Formula : C51H79NO13

  • Molecular Weight : 914.17

stdClass Object
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    [pname] => Rapamycin Dialdehyde
    [catalogue_number] => PA 18 26510
    [category_ids] => ,69,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 946.17
    [form] => C51H79NO15
    [cas] => 500733-49-3
    [pslug] => 500733-49-3-rapamycin-dialdehyde-pa1826510
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PA 18 26510

Rapamycin Dialdehyde


  • Catalogue No.:PA 18 26510

  • CAS :

    500733-49-3

  • Molecular Formula : C51H79NO15

  • Molecular Weight : 946.17

stdClass Object
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    [pname] => Seco Rapamycin
    [catalogue_number] => PA 18 26550
    [category_ids] => 82,81,78,71,70,69
    [chemical_name] => 
    [weight] => 914.17
    [form] => C51H79NO13
    [cas] => 147438-27-5
    [pslug] => 147438-27-5-seco-rapamycin-pa1826550
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PA 18 26550

Seco Rapamycin


  • Catalogue No.:PA 18 26550

  • CAS :

    147438-27-5

  • Molecular Formula : C51H79NO13

  • Molecular Weight : 914.17

stdClass Object
(
    [pname] => 28-epi-Rapamycin
    [catalogue_number] => PA 18 26600
    [category_ids] => ,69,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 914.17
    [form] => C51H79NO13
    [cas] => 253431-35-5
    [pslug] => 253431-35-5-28-epi-rapamycin-pa1826600
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PA 18 26600

28-epi-Rapamycin


  • Catalogue No.:PA 18 26600

  • CAS :

    253431-35-5

  • Molecular Formula : C51H79NO13

  • Molecular Weight : 914.17

stdClass Object
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    [pname] => 29-Desmethoxy-rapamycin
    [catalogue_number] => PA 18 26610
    [category_ids] => ,69,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 884.15
    [form] => C50H77NO12
    [cas] => NA
    [pslug] => 29-desmethoxy-rapamycin-pa1826610
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PA 18 26610

29-Desmethoxy-rapamycin


  • Catalogue No.:PA 18 26610

  • CAS :

    NA

  • Molecular Formula : C50H77NO12

  • Molecular Weight : 884.15

stdClass Object
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    [pname] => 12-Ethyl Rapamycin
    [catalogue_number] => PA 18 26620
    [category_ids] => ,69,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 928.2
    [form] => C52H81NO13
    [cas] => NA
    [pslug] => 12-ethyl-rapamycin-pa1826620
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PA 18 26620

12-Ethyl Rapamycin


  • Catalogue No.:PA 18 26620

  • CAS :

    NA

  • Molecular Formula : C52H81NO13

  • Molecular Weight : 928.2

stdClass Object
(
    [pname] => 33-Ethyl Rapamycin
    [catalogue_number] => PA 18 26630
    [category_ids] => ,69,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 928.2
    [form] => C52H81NO13
    [cas] => NA
    [pslug] => 33-ethyl-rapamycin-pa1826630
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PA 18 26630

33-Ethyl Rapamycin


  • Catalogue No.:PA 18 26630

  • CAS :

    NA

  • Molecular Formula : C52H81NO13

  • Molecular Weight : 928.2

stdClass Object
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    [pname] => 42-O-tert-Butyldimethylsilyloxyethyl-d4 Rapamycin
    [catalogue_number] => PA STI 016250
    [category_ids] => ,69,71,98,
    [chemical_name] => 
    [weight] => 1076.51
    [form] => C59H93D4NO14Si
    [cas] => 1356839-88-7
    [pslug] => 1356839-88-7-42-o-tert-butyldimethylsilyloxyethyl-d4-rapamycin-pasti016250
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PA STI 016250

42-O-tert-Butyldimethylsilyloxyethyl-d4 Rapamycin


  • Catalogue No.:PA STI 016250

  • CAS :

    1356839-88-7

  • Molecular Formula : C59H93D4NO14Si

  • Molecular Weight : 1076.51

stdClass Object
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    [pname] => (9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13S,14R,15E)-14-hydroxy-2,13-dimethoxy-3,9,11,15-tetramethyl-12,17-dioxooctadeca-3,5,7,15-tetraen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione
    [catalogue_number] => PA 18 0261012
    [category_ids] => ,82,81,78,71,70,69,
    [chemical_name] => 
    [weight] => 703.87
    [form] => C38H57NO11
    [cas] => NA
    [pslug] => 9as-3-hydroxy-3-2r-3r-6s-2-hydroxy-6-2s-3e-5e-7e-9s-11r-13s-14r-15e-14-hydroxy-2-13-dimethoxy-3-9-11-15-tetramethyl-12-17-dioxooctadeca-3-5-7-15-tetraen-1-yl-3-methyltetrahydro-2h-pyran-2-yl-tetrahydropyrido-2-1-c-1-4-oxazine-1-4-3h-6h-dione-pa180261012
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PA 18 0261012

(9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13S,14R,15E)-14-hydroxy-2,13-dimethoxy-3,9,11,15-tetramethyl-12,17-dioxooctadeca-3,5,7,15-tetraen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione


  • Catalogue No.:PA 18 0261012

  • CAS :

    NA

  • Molecular Formula : C38H57NO11

  • Molecular Weight : 703.87

stdClass Object
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    [pname] => (3R,9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione
    [catalogue_number] => PA 18 0261015
    [category_ids] => ,82,81,78,71,70,69,
    [chemical_name] => 
    [weight] => 914.19
    [form] => C51H79NO13
    [cas] => NA
    [pslug] => 3r-9as-3-hydroxy-3-2r-3r-6s-2-hydroxy-6-2s-3e-5e-7e-9s-11r-13r-14r-15e-17r-19e-21r-14-hydroxy-22-1s-3r-4r-4-hydroxy-3-methoxycyclohexyl-2-13-dimethoxy-3-9-11-15-17-21-hexamethyl-12-18-dioxodocosa-3-5-7-15-19-pentaen-1-yl-3-methyltetrahydro-2h-pyran-2-yl-tetrahydropyrido-2-1-c-1-4-oxazine-1-4-3h-6h-dione-pa180261015
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PA 18 0261015

(3R,9aS)-3-Hydroxy-3-((2R,3R,6S)-2-hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)tetrahydropyrido[2,1-c][1,4]oxazine-1,4(3H,6H)-dione


  • Catalogue No.:PA 18 0261015

  • CAS :

    NA

  • Molecular Formula : C51H79NO13

  • Molecular Weight : 914.19