A multikinase inhibitor, Regorafenib is used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors. Shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.Reference standards of Regorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Regorafenib - API Standards [catalogue_number] => PA 18 49000 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 482.82 [form] => C21H15ClF4N4O3 [cas] => 755037-03-7 [pslug] => 755037-03-7-regorafenib-api-pa1849000 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49000
CAS :
Molecular Formula : C21H15ClF4N4O3
Molecular Weight : 482.82
stdClass Object ( [pname] => Regorafenib N-Oxide [catalogue_number] => PA 18 49510 [category_ids] => ,79,80,71,76,75,78,70,82, [chemical_name] => [weight] => 498.81 [form] => C21H15ClF4N4O4 [cas] => 835621-11-9 [pslug] => 835621-11-9-regorafenib-n-oxide-pa1849510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49510
Molecular Formula : C21H15ClF4N4O4
Molecular Weight : 498.81
stdClass Object ( [pname] => 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide [catalogue_number] => PA 18 49520 [category_ids] => ,79,80,71,76,75,78,70,82,89, [chemical_name] => [weight] => 491.45 [form] => C25H19F2N5O4 [cas] => 2518234-85-8 [pslug] => 2518234-85-8-4-4-amino-3-fluorophenoxy-n-2-fluoro-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-picolinamide-pa1849520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49520
Molecular Formula : C25H19F2N5O4
Molecular Weight : 491.45
stdClass Object ( [pname] => Hydroxyregorafenib [catalogue_number] => PA 18 49530 [category_ids] => ,79,80,71,76,75,78,70,82, [chemical_name] => [weight] => 498.81 [form] => C21H15ClF4N4O4 [cas] => 1343498-71-4 [pslug] => 1343498-71-4-hydroxyregorafenib-pa1849530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49530
stdClass Object ( [pname] => 4-Dechloro-2-chloro-Regorafenib [catalogue_number] => PA 18 49540 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 482.82 [form] => C21H15ClF4N4O3 [cas] => NA [pslug] => 4-dechloro-2-chloro-regorafenib-pa1849540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49540
stdClass Object ( [pname] => Regorafenib - Impurity C [catalogue_number] => PA 18 49550 [category_ids] => 79,80,71,75 [chemical_name] => [weight] => 395.39 [form] => C20H18FN5O3 [cas] => 1855006-12-0 [pslug] => 1855006-12-0-regorafenib-impurity-c-pa1849550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49550
Molecular Formula : C20H18FN5O3
Molecular Weight : 395.39
stdClass Object ( [pname] => Regorafenib - Impurity D [catalogue_number] => PA 18 49560 [category_ids] => 89,79,71,75,80 [chemical_name] => [weight] => 548.5 [form] => C27H22F2N6O5 [cas] => 2438857-80-6 [pslug] => 2438857-80-6-regorafenib-impurity-d-pa1849560 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49560
Molecular Formula : C27H22F2N6O5
Molecular Weight : 548.5
stdClass Object ( [pname] => 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic Acid [catalogue_number] => PA 18 49570 [category_ids] => ,71,75,79,80,89, [chemical_name] => [weight] => 469.77 [form] => C20H12ClF4N3O4 [cas] => 1187945-05-6 [pslug] => 1187945-05-6-4-4-3-4-chloro-3-trifluoromethyl-phenyl-ureido-3-fluorophenoxy-picolinic-acid-pa1849570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49570
Molecular Formula : C20H12ClF4N3O4
Molecular Weight : 469.77
stdClass Object ( [pname] => N-Desmethyl Regorafenib [catalogue_number] => PA 18 49580 [category_ids] => 82,80,79,78,76,75,71,70 [chemical_name] => [weight] => 468.79 [form] => C20H13ClF4N4O3 [cas] => 1343498-72-5 [pslug] => 1343498-72-5-n-desmethyl-regorafenib-pa1849580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49580
Molecular Formula : C20H13ClF4N4O3
Molecular Weight : 468.79
stdClass Object ( [pname] => Regorafenib Tablets EP Impurity FP-A [catalogue_number] => PA 18 49630 [category_ids] => ,80,71,76,75,78,70,82, [chemical_name] => [weight] => 333.31 [form] => C16H16FN3O4 [cas] => 2514957-39-0 [pslug] => 2514957-39-0-regorafenib-tablets-ep-impurity-fp-a-pa1849630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 49630
Molecular Formula : C16H16FN3O4
Molecular Weight : 333.31
stdClass Object ( [pname] => 4,4'-((2-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)azanediyl)bis(N-methylpicolinamide) [catalogue_number] => PA 18 0491004 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 529.53 [form] => C27H24FN7O4 [cas] => NA [pslug] => 4-4-2-fluoro-4-2-methylcarbamoyl-pyridin-4-yl-oxy-phenyl-azanediyl-bis-n-methylpicolinamide-pa180491004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491004
Molecular Formula : C27H24FN7O4
Molecular Weight : 529.53
stdClass Object ( [pname] => 4-Chloro-N-methyl-6-(methylamino)picolinamide [catalogue_number] => PA 18 0491005 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 199.64 [form] => C8H10ClN3O [cas] => 1446410-29-2 [pslug] => 1446410-29-2-4-chloro-n-methyl-6-methylamino-picolinamide-pa180491005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491005
Molecular Formula : C8H10ClN3O
Molecular Weight : 199.64
stdClass Object ( [pname] => 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-ethylurea [catalogue_number] => PA 18 0491006 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 266.65 [form] => C10H10ClF3N2O [cas] => 2711-21-9 [pslug] => 2711-21-9-1-4-chloro-3-trifluoromethyl-phenyl-3-ethylurea-pa180491006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491006
Molecular Formula : C10H10ClF3N2O
Molecular Weight : 266.65
stdClass Object ( [pname] => 4-(4-Amino-3-(4-amino-3-fluorophenoxy)phenoxy)-N-methylpicolinamide [catalogue_number] => PA 18 0491007 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 368.37 [form] => C19H17FN4O3 [cas] => 2098799-12-1 [pslug] => 2098799-12-1-4-4-amino-3-4-amino-3-fluorophenoxy-phenoxy-n-methylpicolinamide-pa180491007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491007
Molecular Formula : C19H17FN4O3
Molecular Weight : 368.37
stdClass Object ( [pname] => 4-(4-Amino-3-fluorophenoxy)picolinic Acid [catalogue_number] => PA 18 0491008 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 248.21 [form] => C12H9FN2O3 [cas] => 2817629-89-1 [pslug] => 2817629-89-1-4-4-amino-3-fluorophenoxy-picolinic-acid-pa180491008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491008
Molecular Formula : C12H9FN2O3
Molecular Weight : 248.21
stdClass Object ( [pname] => Methyl 4-(4-amino-3-fluorophenoxy)pyridine-2-carboxylate [catalogue_number] => PA 18 0491009 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 262.24 [form] => C13H11FN2O3 [cas] => 864245-61-4 [pslug] => 864245-61-4-methyl-4-4-amino-3-fluorophenoxy-pyridine-2-carboxylate-pa180491009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491009
Molecular Formula : C13H11FN2O3
Molecular Weight : 262.24
stdClass Object ( [pname] => Ethyl 4-(4-amino-3-fluorophenoxy)picolinate [catalogue_number] => PA 18 0491010 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 276.27 [form] => C14H13FN2O3 [cas] => 2817629-88-0 [pslug] => 2817629-88-0-ethyl-4-4-amino-3-fluorophenoxy-picolinate-pa180491010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491010
Molecular Formula : C14H13FN2O3
Molecular Weight : 276.27
stdClass Object ( [pname] => 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-hydroxyphenyl)urea [catalogue_number] => PA 18 0491011 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 348.68 [form] => C14H9ClF4N2O2 [cas] => 1333390-56-9 [pslug] => 1333390-56-9-1-4-chloro-3-trifluoromethyl-phenyl-3-2-fluoro-4-hydroxyphenyl-urea-pa180491011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491011
Molecular Formula : C14H9ClF4N2O2
Molecular Weight : 348.68
stdClass Object ( [pname] => 3-(4-Chloro-3-(trifluoromethyl)phenyl)-1-((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)-1-(2-fluoro-4-hydroxyphenyl)urea [catalogue_number] => PA 18 0491012 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 570.24 [form] => C22H12Cl2F7N3O3 [cas] => NA [pslug] => 3-4-chloro-3-trifluoromethyl-phenyl-1-4-chloro-3-trifluoromethyl-phenyl-carbamoyl-1-2-fluoro-4-hydroxyphenyl-urea-pa180491012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491012
Molecular Formula : C22H12Cl2F7N3O3
Molecular Weight : 570.24
stdClass Object ( [pname] => 4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate [catalogue_number] => PA 18 0491013 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 570.24 [form] => C22H12Cl2F7N3O3 [cas] => 2518416-73-2 [pslug] => 2518416-73-2-4-3-4-chloro-3-trifluoromethyl-phenyl-ureido-3-fluorophenyl-4-chloro-3-trifluoromethyl-phenyl-carbamate-pa180491013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491013
stdClass Object ( [pname] => 1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)-1-((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)urea [catalogue_number] => PA 18 0491014 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 638.7 [form] => C23H11Cl3F9N3O2 [cas] => NA [pslug] => 1-3-bis-4-chloro-3-trifluoromethyl-phenyl-1-4-chloro-3-trifluoromethyl-phenyl-carbamoyl-urea-pa180491014 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491014
Molecular Formula : C23H11Cl3F9N3O2
Molecular Weight : 638.7
stdClass Object ( [pname] => 4,5,6-trichloro-N-methylpicolinamide [catalogue_number] => PA 18 0491015 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 239.48 [form] => C7H5Cl3N2O [cas] => NA [pslug] => 4-5-6-trichloro-n-methylpicolinamide-pa180491015 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491015
Molecular Formula : C7H5Cl3N2O
Molecular Weight : 239.48
stdClass Object ( [pname] => 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-6-hydroxyphenyl)urea [catalogue_number] => PA 18 0491016 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 348.68 [form] => C14H9ClF4N2O2 [cas] => NA [pslug] => 1-4-chloro-3-trifluoromethyl-phenyl-3-2-fluoro-6-hydroxyphenyl-urea-pa180491016 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491016
stdClass Object ( [pname] => 4-Hydroxy-N-methylpicolinamide [catalogue_number] => PA 18 0491017 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 152.15 [form] => C7H8N2O2 [cas] => 611226-36-9 [pslug] => 611226-36-9-4-hydroxy-n-methylpicolinamide-pa180491017 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0491017
Molecular Formula : C7H8N2O2
Molecular Weight : 152.15
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