Sunitinib-impurities | Pharmaffiliates

sunitinib

An oral anti cancer drug. Works by inhibiting cellular signals by targeting multiple receptor tyrosine kinases (RTKs). Sunitinib is approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) Reference standards of Sunitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Sunitinib - API Standards 
    [catalogue_number] => PA 19 75000
    [category_ids] => 117,82,78,71,70
    [chemical_name] => 
    [weight] => 398.47
    [form] => C22H27FN4O2
    [cas] => 557795-19-4
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PA 19 75000

Sunitinib - API Standards


  • Catalogue No.:PA 19 75000

  • CAS :

    557795-19-4

  • Molecular Formula : C22H27FN4O2

  • Molecular Weight : 398.47

stdClass Object
(
    [pname] => (Z)-N-Ethyl-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]- 2,4-dimethyl-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 19 75520
    [category_ids] => 89,82,80,79,78,71,70
    [chemical_name] => 
    [weight] => 327.35
    [form] => C18H18FN3O2
    [cas] => NA
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PA 19 75520

(Z)-N-Ethyl-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]- 2,4-dimethyl-1H-pyrrole-3-carboxamide


  • Catalogue No.:PA 19 75520

  • CAS :

    NA

  • Molecular Formula : C18H18FN3O2

  • Molecular Weight : 327.35

stdClass Object
(
    [pname] => Sunitinib L-Malate - API Standards 
    [catalogue_number] => PA 19 75530
    [category_ids] => 117,82,78,71,70
    [chemical_name] => 
    [weight] => 532.56
    [form] => C26H33FN4O7
    [cas] => 341031-54-7
    [pslug] => 341031-54-7-sunitinib-malate-pa1975530
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PA 19 75530

Sunitinib L-Malate - API Standards


  • Catalogue No.:PA 19 75530

  • CAS :

    341031-54-7

  • Molecular Formula : C26H33FN4O7

  • Molecular Weight : 532.56

stdClass Object
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    [pname] => Sunitinib N-oxide
    [catalogue_number] => PA 19 75540
    [category_ids] => 117,71,82,78,70
    [chemical_name] => 
    [weight] => 414.47
    [form] => C22H27FN4O3
    [cas] => 356068-99-0
    [pslug] => 356068-99-0-sunitinib-n-oxide-pa1975540
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PA 19 75540

Sunitinib N-oxide


  • Catalogue No.:PA 19 75540

  • CAS :

    356068-99-0

  • Molecular Formula : C22H27FN4O3

  • Molecular Weight : 414.47

stdClass Object
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    [pname] => (E)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 19 75570
    [category_ids] => 117,82,78,71,70
    [chemical_name] => 
    [weight] => 398.47
    [form] => C22H27FN4O2
    [cas] => 1691223-83-2
    [pslug] => 1691223-83-2-e-n-2-diethylamino-ethyl-5-5-fluoro-2-oxoindolin-3-ylidene-methyl-2-4-dimethyl-1h-pyrrole-3-carboxamide-pa1975570
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PA 19 75570

(E)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide


  • Catalogue No.:PA 19 75570

  • CAS :

    1691223-83-2

  • Molecular Formula : C22H27FN4O2

  • Molecular Weight : 398.47

stdClass Object
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    [pname] => Sunitinib-d10
    [catalogue_number] => PA STI 080680
    [category_ids] => ,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 408.54
    [form] => C22H17D10FN4O2
    [cas] => 1126721-82-1
    [pslug] => 1126721-82-1-sunitinib-d10-pasti080680
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PA STI 080680

Sunitinib-d10


  • Catalogue No.:PA STI 080680

  • CAS :

    1126721-82-1

  • Molecular Formula : C22H17D10FN4O2

  • Molecular Weight : 408.54

stdClass Object
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    [pname] => Sunitinib-d4
    [catalogue_number] => PA STI 080690
    [category_ids] => ,71,98,78,70,82,117,
    [chemical_name] => 
    [weight] => 402.50
    [form] => C22H23D4FN4O2
    [cas] => 1126721-79-6
    [pslug] => 1126721-79-6-sunitinib-d4-pasti080690
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PA STI 080690

Sunitinib-d4


  • Catalogue No.:PA STI 080690

  • CAS :

    1126721-79-6

  • Molecular Formula : C22H23D4FN4O2

  • Molecular Weight : 402.50

stdClass Object
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    [pname] => 5-Fluoroindolin-2-one
    [catalogue_number] => PA 19 75600
    [category_ids] => ,80,71,
    [chemical_name] => 
    [weight] => 151.14
    [form] => C8H6FNO
    [cas] => 56341-41-4
    [pslug] => 56341-41-4-5-fluoroindolin-2-one-pa1975600
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PA 19 75600

5-Fluoroindolin-2-one


  • Catalogue No.:PA 19 75600

  • CAS :

    56341-41-4

  • Molecular Formula : C8H6FNO

  • Molecular Weight : 151.14

stdClass Object
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    [pname] => N,N-Dimethyl Sunitinib
    [catalogue_number] => PA 19 75640
    [category_ids] => ,71,78,70,82,117,
    [chemical_name] => 
    [weight] => 370.43
    [form] => C20H23FN4O2
    [cas] => 326914-17-4
    [pslug] => 326914-17-4-n-n-dimethyl-sunitinib-pa1975640
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PA 19 75640

N,N-Dimethyl Sunitinib


  • Catalogue No.:PA 19 75640

  • CAS :

    326914-17-4

  • Molecular Formula : C20H23FN4O2

  • Molecular Weight : 370.43

stdClass Object
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    [pname] => (Z)-N-(3-(Dimethylamino)propyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 19 0751017
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 384.46
    [form] => C21H25FN4O2
    [cas] => 2417674-06-5
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PA 19 0751017

(Z)-N-(3-(Dimethylamino)propyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide


  • Catalogue No.:PA 19 0751017

  • CAS :

    2417674-06-5

  • Molecular Formula : C21H25FN4O2

  • Molecular Weight : 384.46

stdClass Object
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    [pname] => N-Ethyl-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 19 0751018
    [category_ids] => ,71,78,82,75,76,
    [chemical_name] => 
    [weight] => 327.36
    [form] => C18H18FN3O2
    [cas] => 1467015-10-6
    [pslug] => 1467015-10-6-n-ethyl-5-5-fluoro-2-oxoindolin-3-ylidene-methyl-2-4-dimethyl-1h-pyrrole-3-carboxamide-pa190751018
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PA 19 0751018

N-Ethyl-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide


  • Catalogue No.:PA 19 0751018

  • CAS :

    1467015-10-6

  • Molecular Formula : C18H18FN3O2

  • Molecular Weight : 327.36

stdClass Object
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    [pname] => N-Nitroso N-Desethyl Sunitinib
    [catalogue_number] => PA 19 0751019
    [category_ids] => ,70,71,78,82,117,162,
    [chemical_name] => 
    [weight] => 399.43
    [form] => C20H22FN5O3
    [cas] => NA
    [pslug] => n-nitroso-n-desethyl-sunitinib-pa190751019
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PA 19 0751019

N-Nitroso N-Desethyl Sunitinib


  • Catalogue No.:PA 19 0751019

  • CAS :

    NA

  • Molecular Formula : C20H22FN5O3

  • Molecular Weight : 399.43

stdClass Object
(
    [pname] => (Z)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1-nitroso-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 19 0751020
    [category_ids] => ,82,78,71,70,162,
    [chemical_name] => 
    [weight] => 427.48
    [form] => C22H26FN5O3
    [cas] => NA
    [pslug] => z-n-2-diethylamino-ethyl-5-5-fluoro-2-oxoindolin-3-ylidene-methyl-2-4-dimethyl-1-nitroso-1h-pyrrole-3-carboxamide-pa190751020
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PA 19 0751020

(Z)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1-nitroso-1H-pyrrole-3-carboxamide


  • Catalogue No.:PA 19 0751020

  • CAS :

    NA

  • Molecular Formula : C22H26FN5O3

  • Molecular Weight : 427.48