Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer. Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Avanafil Keto Analog [catalogue_number] => PA 28 44590 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 400.82 [form] => C18H17ClN6O3 [cas] => 1452128-53-8 [pslug] => 1452128-53-8-avanafil-keto-analog-pa2844590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44590
CAS :
Molecular Formula : C18H17ClN6O3
Molecular Weight : 400.82
stdClass Object ( [pname] => Avanafi Dichloro Analog [catalogue_number] => PA 28 44620 [category_ids] => ,80,71,78,70,82,79,75, [chemical_name] => [weight] => 518.4 [form] => C23H25Cl2N7O3 [cas] => 2520113-66-8 [pslug] => 2520113-66-8-avanafi-dichloro-analog-pa2844620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44620
Molecular Formula : C23H25Cl2N7O3
Molecular Weight : 518.4
stdClass Object ( [pname] => (1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine [catalogue_number] => PA 28 44630 [category_ids] => ,80,79,84,75, [chemical_name] => [weight] => 113.16 [form] => C5H11N3 [cas] => 759408-08-7 [pslug] => 759408-08-7-1-4-5-6-tetrahydropyrimidin-2-yl-methanamine-pa2844630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44630
Molecular Formula : C5H11N3
Molecular Weight : 113.16
stdClass Object ( [pname] => 4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid [catalogue_number] => PA 28 44640 [category_ids] => ,80,71,78,70,82,79,75, [chemical_name] => [weight] => 515.95 [form] => C23H26ClN7O5 [cas] => 2748151-94-0 [pslug] => 2748151-94-0-4-4-3-chloro-4-methoxybenzyl-amino-5-pyrimidin-2-ylmethyl-carbamoyl-pyrimidin-2-yl-amino-5-hydroxypentanoic-acid-pa2844640 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44640
Molecular Formula : C23H26ClN7O5
Molecular Weight : 515.95
stdClass Object ( [pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid [catalogue_number] => PA 28 44650 [category_ids] => ,80,71,78,70,82,79,75,88, [chemical_name] => [weight] => 339.8 [form] => C14H14ClN3O3S [cas] => 330786-34-0 [pslug] => 330786-34-0-4-3-chloro-4-methoxybenzyl-amino-2-methylthio-pyrimidine-5-carboxylic-acid-pa2844650 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44650
Molecular Formula : C14H14ClN3O3S
Molecular Weight : 339.8
stdClass Object ( [pname] => Avanafil Isopropyl Amide Analog [catalogue_number] => PA 28 44660 [category_ids] => ,80,71,78,70,82,79,75, [chemical_name] => [weight] => 433.93 [form] => C21H28ClN5O3 [cas] => 2520114-11-6 [pslug] => 2520114-11-6-avanafil-isopropyl-amide-analog-pa2844660 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 44660
Molecular Formula : C21H28ClN5O3
Molecular Weight : 433.93
stdClass Object ( [pname] => Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441000 [category_ids] => ,75,76,70,78,82, [chemical_name] => [weight] => 367.85 [form] => C16H18ClN3O3S [cas] => 2520114-23-0 [pslug] => 2520114-23-0-ethyl-4-2-chloro-4-methoxybenzyl-amino-2-methylthio-pyrimidine-5-carboxylate-pa280441000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441000
Molecular Formula : C16H18ClN3O3S
Molecular Weight : 367.85
stdClass Object ( [pname] => Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441001 [category_ids] => ,75,76,70,78,82, [chemical_name] => [weight] => 402.29 [form] => C16H17Cl2N3O3S [cas] => 2250242-48-7 [pslug] => 2250242-48-7-ethyl-4-3-5-dichloro-4-methoxybenzyl-amino-2-methylthio-pyrimidine-5-carboxylate-pa280441001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441001
Molecular Formula : C16H17Cl2N3O3S
Molecular Weight : 402.29
stdClass Object ( [pname] => Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 337.76 [form] => C15H16ClN3O4 [cas] => 330785-99-4 [pslug] => 330785-99-4-ethyl-4-3-chloro-4-methoxybenzyl-amino-2-methylthio-pyrimidine-5-carboxylate-pa280441002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441002
Molecular Formula : C15H16ClN3O4
Molecular Weight : 337.76
stdClass Object ( [pname] => (S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 420.89 [form] => C20H25ClN4O4 [cas] => 330785-83-6 [pslug] => 330785-83-6-s-ethyl-4-3-chloro-4-methoxybenzylamino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441004
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
stdClass Object ( [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide [catalogue_number] => PA 28 0441005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 487.99 [form] => C23H30ClN7O3 [cas] => NA [pslug] => s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-n-1-4-5-6-tetrahydropyrimidin-2-yl-methyl-pyrimidine-5-carboxamide-pa280441005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441005
Molecular Formula : C23H30ClN7O3
Molecular Weight : 487.99
stdClass Object ( [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide [catalogue_number] => PA 28 0441006 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 576.06 [form] => C28H30ClN9O3 [cas] => NA [pslug] => s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-n-n-bis-pyrimidin-2-ylmethyl-pyrimidine-5-carboxamide-pa280441006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441006
Molecular Formula : C28H30ClN9O3
Molecular Weight : 576.06
stdClass Object ( [pname] => (R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide [catalogue_number] => PA 28 0441007 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 449.52 [form] => C23H27N7O3 [cas] => 2250242-21-6 [pslug] => 2250242-21-6-r-2-2-hydroxymethyl-pyrrolidin-1-yl-4-4-methoxybenzyl-amino-n-pyrimidin-2-ylmethyl-pyrimidine-5-carboxamide-pa280441007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441007
Molecular Formula : C23H27N7O3
Molecular Weight : 449.52
stdClass Object ( [pname] => 1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441008 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 509.95 [form] => C24H24ClN7O4 [cas] => 2520113-98-6 [pslug] => 2520113-98-6-1h-benzo-d-1-2-3-triazol-1-yl-s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441008
Molecular Formula : C24H24ClN7O4
Molecular Weight : 509.95
stdClass Object ( [pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid [catalogue_number] => PA 28 0441009 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 767.67 [form] => C36H40Cl2N8O7 [cas] => 2520114-03-6 [pslug] => 2520114-03-6-4-3-chloro-4-methoxybenzyl-amino-2-s-2-4-3-chloro-4-methoxybenzyl-amino-2-s-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carbonyl-oxy-methyl-pyrrolidin-1-yl-pyrimidine-5-carboxylic-acid-pa280441009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441009
Molecular Formula : C36H40Cl2N8O7
Molecular Weight : 767.67
stdClass Object ( [pname] => (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide [catalogue_number] => PA 28 0441010 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 519.04 [form] => C25H35ClN6O4 [cas] => 2520114-17-2 [pslug] => 2520114-17-2-s-4-3-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-n-isopropyl-n-isopropylcarbamoyl-pyrimidine-5-carboxamide-pa280441010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441010
Molecular Formula : C25H35ClN6O4
Molecular Weight : 519.04
stdClass Object ( [pname] => Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441011 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 455.34 [form] => C20H24Cl2N4O4 [cas] => 2520114-19-4 [pslug] => 2520114-19-4-ethyl-s-4-3-5-dichloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441011
Molecular Formula : C20H24Cl2N4O4
Molecular Weight : 455.34
stdClass Object ( [pname] => (S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid [catalogue_number] => PA 28 0441012 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 427.28 [form] => C18H20Cl2N4O4 [cas] => 1643811-26-0 [pslug] => 1643811-26-0s-4-3-5-dichloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylic-acid-pa280441012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441012
Molecular Formula : C18H20Cl2N4O4
Molecular Weight : 427.28
stdClass Object ( [pname] => Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate [catalogue_number] => PA 28 0441013 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 420.89 [form] => C20H25ClN4O4 [cas] => 2520114-28-5 [pslug] => 2520114-28-5-ethyl-s-4-2-chloro-4-methoxybenzyl-amino-2-2-hydroxymethyl-pyrrolidin-1-yl-pyrimidine-5-carboxylate-pa280441013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441013
stdClass Object ( [pname] => 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide [catalogue_number] => PA 28 0441014 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 446.91 [form] => C19H19ClN6O3S [cas] => 1364671-52-2 [pslug] => 1364671-52-2-4-3-chloro-4-methoxybenzyl-amino-2-methylsulfinyl-n-pyrimidin-2-ylmethyl-pyrimidine-5-carboxamide-pa280441014 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441014
Molecular Formula : C19H19ClN6O3S
Molecular Weight : 446.91
stdClass Object ( [pname] => Avanafil D4 [catalogue_number] => PA STI 089027 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 487.98 [form] => C23H22D4ClN7O3 [cas] => 2012598-68-2 [pslug] => 2012598-68-2-avanafil-d4-pasti089027 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 089027
Molecular Formula : C23H22D4ClN7O3
Molecular Weight : 487.98
stdClass Object ( [pname] => Avanafil Diamine Impurity [catalogue_number] => PA 28 0441015 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 554.43 [form] => C26H25Cl2N7O3 [cas] => 1643811-29-3 [pslug] => 1643811-29-3-avanafil-diamine-impurity-pa280441015 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 28 0441015
Molecular Formula : C26H25Cl2N7O3
Molecular Weight : 554.43
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