Gefitinib-impurities | Pharmaffiliates

gefitinib

Gefitinib is used to treat lung cancer. Acting in a similar manner to erlotinib gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. Reference standards of Gefitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => O-Desmorpholinopropyl Gefitinib
    [catalogue_number] => PA 07 24540
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 319.72
    [form] => C15H11ClFN3O2
    [cas] => 184475-71-6
    [pslug] => 184475-71-6-o-desmorpholinopropyl-gefitinib-pa0724540
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PA 07 24540

O-Desmorpholinopropyl Gefitinib


  • Catalogue No.:PA 07 24540

  • CAS :

    184475-71-6

  • Molecular Formula : C15H11ClFN3O2

  • Molecular Weight : 319.72

stdClass Object
(
    [pname] => N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine
    [catalogue_number] => PA 07 24550
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 462.9
    [form] => C22H24ClFN4O4
    [cas] => NA
    [pslug] => n-3-chloro-4-fluorophenyl-n-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-yl-hydroxylamine-pa0724550
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PA 07 24550

N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)hydroxylamine


  • Catalogue No.:PA 07 24550

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O4

  • Molecular Weight : 462.9

stdClass Object
(
    [pname] => 4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide
    [catalogue_number] => PA 07 24560
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 478.9
    [form] => C22H24ClFN4O5
    [cas] => NA
    [pslug] => 4-3-4-3-chloro-4-fluorophenyl-hydroxy-amino-7-methoxyquinazolin-6-yl-oxy-propyl-morpholine-4-oxide-pa0724560
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PA 07 24560

4-(3-((4-((3-Chloro-4-fluorophenyl)(hydroxy)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide


  • Catalogue No.:PA 07 24560

  • CAS :

    NA

  • Molecular Formula : C22H24ClFN4O5

  • Molecular Weight : 478.9

stdClass Object
(
    [pname] => N-(3-Morpholinopropyl) Gefitinib
    [catalogue_number] => PA 07 24580
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 574.09
    [form] => C29H37ClFN5O4
    [cas] => 1502829-45-9
    [pslug] => 1502829-45-9-n-3-morpholinopropyl-gefitinib-pa0724580
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PA 07 24580

N-(3-Morpholinopropyl) Gefitinib


  • Catalogue No.:PA 07 24580

  • CAS :

    1502829-45-9

  • Molecular Formula : C29H37ClFN5O4

  • Molecular Weight : 574.09

stdClass Object
(
    [pname] => N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
    [catalogue_number] => PA 07 24590
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 333.74
    [form] => C16H13ClFN3O2
    [cas] => 153437-78-6
    [pslug] => 153437-78-6-n-3-chloro-4-fluorophenyl-6-7-dimethoxyquinazolin-4-amine-pa0724590
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PA 07 24590

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine


  • Catalogue No.:PA 07 24590

  • CAS :

    153437-78-6

  • Molecular Formula : C16H13ClFN3O2

  • Molecular Weight : 333.74

stdClass Object
(
    [pname] => N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24600
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 412.46
    [form] => C22H25FN4O3
    [cas] => 2254241-82-0
    [pslug] => 2254241-82-0-n-4-fluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724600
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PA 07 24600

N-(4-Fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine


  • Catalogue No.:PA 07 24600

  • CAS :

    2254241-82-0

  • Molecular Formula : C22H25FN4O3

  • Molecular Weight : 412.46

stdClass Object
(
    [pname] => 4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine
    [catalogue_number] => PA 07 24610
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 337.8
    [form] => C16H20ClN3O3
    [cas] => 199327-59-8
    [pslug] => 199327-59-8-4-3-4-chloro-7-methoxyquinazolin-6-yl-oxy-propyl-morpholine-pa0724610
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PA 07 24610

4-(3-((4-Chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine


  • Catalogue No.:PA 07 24610

  • CAS :

    199327-59-8

  • Molecular Formula : C16H20ClN3O3

  • Molecular Weight : 337.8

stdClass Object
(
    [pname] => O-Desmethyl Gefitinib
    [catalogue_number] => PA 07 24620
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 432.88
    [form] => C21H22ClFN4O3
    [cas] => 847949-49-9
    [pslug] => 847949-49-9-o-desmethyl-gefitinib-pa0724620
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PA 07 24620

O-Desmethyl Gefitinib


  • Catalogue No.:PA 07 24620

  • CAS :

    847949-49-9

  • Molecular Formula : C21H22ClFN4O3

  • Molecular Weight : 432.88

stdClass Object
(
    [pname] => N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24630
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 430.45
    [form] => C22H24F2N4O3
    [cas] => 184475-50-1
    [pslug] => 184475-50-1-n-3-4-difluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724630
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PA 07 24630

N-(3,4-Difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine


  • Catalogue No.:PA 07 24630

  • CAS :

    184475-50-1

  • Molecular Formula : C22H24F2N4O3

  • Molecular Weight : 430.45

stdClass Object
(
    [pname] => 4-Defluoro-4-hydroxy Gefitinib
    [catalogue_number] => PA 07 24640
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 444.91
    [form] => C22H25ClN4O4
    [cas] => 847949-50-2
    [pslug] => 847949-50-2-4-defluoro-4-hydroxy-gefitinib-pa0724640
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PA 07 24640

4-Defluoro-4-hydroxy Gefitinib


  • Catalogue No.:PA 07 24640

  • CAS :

    847949-50-2

  • Molecular Formula : C22H25ClN4O4

  • Molecular Weight : 444.91

stdClass Object
(
    [pname] => N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24650
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 463.36
    [form] => C22H24Cl2N4O3
    [cas] => 2089650-13-3
    [pslug] => 2089650-13-3-n-3-4-dichlorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-amine-pa0724650
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PA 07 24650

N-(3,4-Dichlorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine


  • Catalogue No.:PA 07 24650

  • CAS :

    2089650-13-3

  • Molecular Formula : C22H24Cl2N4O3

  • Molecular Weight : 463.36

stdClass Object
(
    [pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate
    [catalogue_number] => PA 07 24660
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 362.74
    [form] => C17H12ClFN2O4
    [cas] => 2512211-98-0
    [pslug] => 2512211-98-0-3-3-chloro-4-fluorophenyl-7-methoxy-4-oxo-3-4-dihydroquinazolin-6-yl-acetate-pa0724660
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PA 07 24660

3-(3-Chloro-4-fluorophenyl)-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl Acetate


  • Catalogue No.:PA 07 24660

  • CAS :

    2512211-98-0

  • Molecular Formula : C17H12ClFN2O4

  • Molecular Weight : 362.74

stdClass Object
(
    [pname] => 3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one
    [catalogue_number] => PA 07 24670
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 447.89
    [form] => C22H23ClFN3O4
    [cas] => 1608115-59-8
    [pslug] => 1608115-59-8-3-3-chloro-4-fluorophenyl-7-methoxy-6-3-morpholinopropoxy-quinazolin-4-3h-one-pa0724670
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PA 07 24670

3-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one


  • Catalogue No.:PA 07 24670

  • CAS :

    1608115-59-8

  • Molecular Formula : C22H23ClFN3O4

  • Molecular Weight : 447.89

stdClass Object
(
    [pname] => 7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine
    [catalogue_number] => PA 07 24680
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 485.77
    [form] => C21H20Cl3FN4O2
    [cas] => NA
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PA 07 24680

7,8-Dichloro-N-(3-chloro-4-fluorophenyl)-6-(3-morpholinopropoxy)quinazolin-4-amine


  • Catalogue No.:PA 07 24680

  • CAS :

    NA

  • Molecular Formula : C21H20Cl3FN4O2

  • Molecular Weight : 485.77

stdClass Object
(
    [pname] => 4-chloro-7-methoxyquinazolin-6-yl acetate
    [catalogue_number] => PA 07 0241000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 252.65
    [form] => C11H9ClN2O3
    [cas] => 230955-75-6
    [pslug] => 230955-75-6-4-chloro-7-methoxyquinazolin-6-yl-acetate-pa070241000
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PA 07 0241000

4-chloro-7-methoxyquinazolin-6-yl acetate


  • Catalogue No.:PA 07 0241000

  • CAS :

    230955-75-6

  • Molecular Formula : C11H9ClN2O3

  • Molecular Weight : 252.65

stdClass Object
(
    [pname] => Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate
    [catalogue_number] => PA 07 0241001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 324.38
    [form] => C16H24N2O5
    [cas] => 214472-41-0
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PA 07 0241001

Methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate


  • Catalogue No.:PA 07 0241001

  • CAS :

    214472-41-0

  • Molecular Formula : C16H24N2O5

  • Molecular Weight : 324.38

stdClass Object
(
    [pname] => Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate
    [catalogue_number] => PA 07 0241002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 354.36
    [form] => C16H22N2O7
    [cas] => 214472-37-4
    [pslug] => 214472-37-4-methyl-4-methoxy-5-3-morpholinopropoxy-2-nitrobenzoate-pa070241002
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PA 07 0241002

Methyl 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzoate


  • Catalogue No.:PA 07 0241002

  • CAS :

    214472-37-4

  • Molecular Formula : C16H22N2O7

  • Molecular Weight : 354.36

stdClass Object
(
    [pname] => Gefitinib Nitroso Impurity
    [catalogue_number] => PA 07 0241003
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 475.91
    [form] => C22H23ClFN5O4
    [cas] => NA
    [pslug] => gefitinib-nitroso-impurity-pa070241003
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PA 07 0241003

Gefitinib Nitroso Impurity


  • Catalogue No.:PA 07 0241003

  • CAS :

    NA

  • Molecular Formula : C22H23ClFN5O4

  • Molecular Weight : 475.91