Imatinib-impurities | Pharmaffiliates

imatinib

Imatinib is a small molecule kinase inhibitor used to treat certain types of cancer. It is occasionally referred to as CGP57148B or STI571. It is used in treating chronic myelogenous leukemia, gastrointestinal stromal tumors and a number of other malignancies. Reference standards of Imatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Imatinib (Pyridine)-N-oxide
    [catalogue_number] => PA 09 05010
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 509.6
    [form] => C29H31N7O2
    [cas] => 571186-92-0
    [pslug] => 571186-92-0-imatinib-pyridine-n-oxide-pa0905010
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PA 09 05010

Imatinib (Pyridine)-N-oxide


  • Catalogue No.:PA 09 05010

  • CAS :

    571186-92-0

  • Molecular Formula : C29H31N7O2

  • Molecular Weight : 509.6

stdClass Object
(
    [pname] => Imatinib (Piperidine)-N,N-DiOxide
    [catalogue_number] => PA 09 05020
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 525.6
    [form] => C29H31N7O3
    [cas] => 571186-93-1
    [pslug] => 571186-93-1-imatinib-piperidine-n-n-dioxide-pa0905020
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PA 09 05020

Imatinib (Piperidine)-N,N-DiOxide


  • Catalogue No.:PA 09 05020

  • CAS :

    571186-93-1

  • Molecular Formula : C29H31N7O3

  • Molecular Weight : 525.6

stdClass Object
(
    [pname] => Imatinib (Piperidine)-N,N-DiOxide Methanesulfonate
    [catalogue_number] => PA 09 05021
    [category_ids] => ,80,71,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 621.71
    [form] => C30H35N7O6S
    [cas] => NA
    [pslug] => imatinib-piperidine-n-n-dioxide-methanesulfonate-pa0905021
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PA 09 05021

Imatinib (Piperidine)-N,N-DiOxide Methanesulfonate


  • Catalogue No.:PA 09 05021

  • CAS :

    NA

  • Molecular Formula : C30H35N7O6S

  • Molecular Weight : 621.71

stdClass Object
(
    [pname] => Imatinib - Impurity D
    [catalogue_number] => PA 09 05040
    [category_ids] => 82,80,78,75,71,70
    [chemical_name] => 
    [weight] => 923.50
    [form] => C53H51ClN12O2
    [cas] => NA
    [pslug] => imatinib-impurity-d-pa0905040
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PA 09 05040

Imatinib - Impurity D


  • Catalogue No.:PA 09 05040

  • CAS :

    NA

  • Molecular Formula : C53H51ClN12O2

  • Molecular Weight : 923.50

stdClass Object
(
    [pname] => 4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride Dichydrochloride
    [catalogue_number] => PA 09 05510
    [category_ids] => 71,75,80,78,70,82
    [chemical_name] => 
    [weight] => 325.66
    [form] => C13H19Cl3N2O
    [cas] => 106261-64-7
    [pslug] => 106261-64-7-4-4-methylpiperazin-1-ylmethyl-benzoyl-chloride-dichydrochloride-pa0905510
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PA 09 05510

4-(4-Methylpiperazin-1-ylmethyl)benzoyl chloride Dichydrochloride


  • Catalogue No.:PA 09 05510

  • CAS :

    106261-64-7

  • Molecular Formula : C13H19Cl3N2O

  • Molecular Weight : 325.66

stdClass Object
(
    [pname] => Imatinib - Impurity F
    [catalogue_number] => PA 09 05520
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 277.32
    [form] => C16H15N5
    [cas] => 152460-10-1
    [pslug] => 152460-10-1-imatinib-impurity-f-pa0905520
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PA 09 05520

Imatinib - Impurity F


  • Catalogue No.:PA 09 05520

  • CAS :

    152460-10-1

  • Molecular Formula : C16H15N5

  • Molecular Weight : 277.32

stdClass Object
(
    [pname] => Imatinib Meta-methyl-piperazine Impurity
    [catalogue_number] => PA 09 05530
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 493.6
    [form] => C29H31N7O
    [cas] => 1246819-59-9
    [pslug] => 1246819-59-9-imatinib-meta-methyl-piperazine-impurity-pa0905530
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PA 09 05530

Imatinib Meta-methyl-piperazine Impurity


  • Catalogue No.:PA 09 05530

  • CAS :

    1246819-59-9

  • Molecular Formula : C29H31N7O

  • Molecular Weight : 493.6

stdClass Object
(
    [pname] => Imatinib (Piperidine)-N4-Oxide
    [catalogue_number] => PA 09 05540
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 509.6
    [form] => C29H31N7O2
    [cas] => 938082-57-6
    [pslug] => 938082-57-6-imatinib-piperidine-n4-oxide-pa0905540
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PA 09 05540

Imatinib (Piperidine)-N4-Oxide


  • Catalogue No.:PA 09 05540

  • CAS :

    938082-57-6

  • Molecular Formula : C29H31N7O2

  • Molecular Weight : 509.6

stdClass Object
(
    [pname] => 1-(Chloromethyl)-1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium chloride
    [catalogue_number] => PA 09 05550
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 578.54
    [form] => C30H33Cl2N7O
    [cas] => NA
    [pslug] => 1-chloromethyl-1-methyl-4-4-4-methyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-phenyl-carbamoyl-benzyl-piperazin-1-ium-chloride-pa0905550
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PA 09 05550

1-(Chloromethyl)-1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium chloride


  • Catalogue No.:PA 09 05550

  • CAS :

    NA

  • Molecular Formula : C30H33Cl2N7O

  • Molecular Weight : 578.54

stdClass Object
(
    [pname] => Imatinib Carboxylic Impurity
    [catalogue_number] => PA 09 05560
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 307.22
    [form] => C13H20Cl2N2O2
    [cas] => 106261-49-8
    [pslug] => 106261-49-8-imatinib-carboxylic-impurity-pa0905560
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PA 09 05560

Imatinib Carboxylic Impurity


  • Catalogue No.:PA 09 05560

  • CAS :

    106261-49-8

  • Molecular Formula : C13H20Cl2N2O2

  • Molecular Weight : 307.22

stdClass Object
(
    [pname] => 4-Methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide methanesulfonate
    [catalogue_number] => PA 09 28510
    [category_ids] => ,80,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 491.56
    [form] => C25H25N5O4S
    [cas] => NA
    [pslug] => 4-methyl-n-4-methyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-phenyl-benzamide-methanesulfonate-pa0928510
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PA 09 28510

4-Methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide methanesulfonate


  • Catalogue No.:PA 09 28510

  • CAS :

    NA

  • Molecular Formula : C25H25N5O4S

  • Molecular Weight : 491.56

stdClass Object
(
    [pname] => Imatinib Meta-methyl-piperazine Impurity-d3
    [catalogue_number] => PA STI 052680
    [category_ids] => ,80,71,75,98,78,70,82,
    [chemical_name] => 
    [weight] => 496.62
    [form] => C29H28D3N7O
    [cas] => 1246819-35-9
    [pslug] => 1246819-35-9-imatinib-meta-methyl-piperazine-impurity-d3-pasti052680
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PA STI 052680

Imatinib Meta-methyl-piperazine Impurity-d3


  • Catalogue No.:PA STI 052680

  • CAS :

    1246819-35-9

  • Molecular Formula : C29H28D3N7O

  • Molecular Weight : 496.62

stdClass Object
(
    [pname] => Imatinib Para-diaminomethylbenzene Impurity-d3
    [catalogue_number] => PA STI 052690
    [category_ids] => ,80,71,75,98,78,70,82,
    [chemical_name] => 
    [weight] => 496.62
    [form] => C29H28D3N7O
    [cas] => 1246819-27-1
    [pslug] => 1246819-27-1-imatinib-para-diaminomethylbenzene-impurity-d3-pasti052690
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PA STI 052690

Imatinib Para-diaminomethylbenzene Impurity-d3


  • Catalogue No.:PA STI 052690

  • CAS :

    1246819-27-1

  • Molecular Formula : C29H28D3N7O

  • Molecular Weight : 496.62

stdClass Object
(
    [pname] => N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
    [catalogue_number] => PA 09 05610
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 277.32
    [form] => C16H15N5
    [cas] => 112696-91-0
    [pslug] => 112696-91-0-n-4-amino-2-methylphenyl-4-3-pyridyl-2-pyrimidineamine-pa0905610
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PA 09 05610

N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine


  • Catalogue No.:PA 09 05610

  • CAS :

    112696-91-0

  • Molecular Formula : C16H15N5

  • Molecular Weight : 277.32

stdClass Object
(
    [pname] => Imatinib para-Diaminomethylbenzene
    [catalogue_number] => PA 09 0051000
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 493.60
    [form] => C29H31N7O
    [cas] => 1026753-54-7
    [pslug] => 1026753-54-7-imatinib-para-diaminomethylbenzene-pa090051000
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PA 09 0051000

Imatinib para-Diaminomethylbenzene


  • Catalogue No.:PA 09 0051000

  • CAS :

    1026753-54-7

  • Molecular Formula : C29H31N7O

  • Molecular Weight : 493.60

stdClass Object
(
    [pname] => Imatinib D4
    [catalogue_number] => PA STI 088698
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 497.64
    [form] => C29H27D4N7O
    [cas] => 1134803-16-9
    [pslug] => 1134803-16-9-imatinib-d4-pasti088698
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PA STI 088698

Imatinib D4


  • Catalogue No.:PA STI 088698

  • CAS :

    1134803-16-9

  • Molecular Formula : C29H27D4N7O

  • Molecular Weight : 497.64

stdClass Object
(
    [pname] => N-Boc-N-Desmethyl Imatinib
    [catalogue_number] => PA 09 0051001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 579.71
    [form] => C33H37N7O3
    [cas] => 1076199-23-9
    [pslug] => 1076199-23-9-n-boc-n-desmethyl-imatinib-pa090051001
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PA 09 0051001

N-Boc-N-Desmethyl Imatinib


  • Catalogue No.:PA 09 0051001

  • CAS :

    1076199-23-9

  • Molecular Formula : C33H37N7O3

  • Molecular Weight : 579.71

stdClass Object
(
    [pname] => 6-Methyl-N1-(4-methyl-6-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
    [catalogue_number] => PA 09 0051002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 291.36
    [form] => C17H17N5
    [cas] => 1032314-73-0
    [pslug] => 1032314-73-0-6-methyl-n1-4-methyl-6-pyridin-3-yl-pyrimidin-2-yl-benzene-1-3-diamine-pa090051002
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PA 09 0051002

6-Methyl-N1-(4-methyl-6-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine


  • Catalogue No.:PA 09 0051002

  • CAS :

    1032314-73-0

  • Molecular Formula : C17H17N5

  • Molecular Weight : 291.36

stdClass Object
(
    [pname] => 4-methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
    [catalogue_number] => PA 09 0051003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 395.47
    [form] => C24H21N5O
    [cas] => 152459-96-6
    [pslug] => 152459-96-6-4-methyl-n-4-methyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-phenyl-benzamide-pa090051003
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PA 09 0051003

4-methyl-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide


  • Catalogue No.:PA 09 0051003

  • CAS :

    152459-96-6

  • Molecular Formula : C24H21N5O

  • Molecular Weight : 395.47

stdClass Object
(
    [pname] => 4-(chloromethyl)benzoic acid
    [catalogue_number] => PA 09 0051004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 170.59
    [form] => C8H7ClO2
    [cas] => 1642-81-5
    [pslug] => 1642-81-5-4-chloromethyl-benzoic-acid-pa090051004
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PA 09 0051004

4-(chloromethyl)benzoic acid


  • Catalogue No.:PA 09 0051004

  • CAS :

    1642-81-5

  • Molecular Formula : C8H7ClO2

  • Molecular Weight : 170.59

stdClass Object
(
    [pname] => N-(2-methyl-5-nitrophenyl)-[3,4'-bipyridin]-2'-amine
    [catalogue_number] => PA 09 0051005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 306.33
    [form] => C17H14N4O2
    [cas] => 641615-50-1
    [pslug] => 641615-50-1-n-2-methyl-5-nitrophenyl-3-4-bipyridin-2-amine-pa090051005
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PA 09 0051005

N-(2-methyl-5-nitrophenyl)-[3,4'-bipyridin]-2'-amine


  • Catalogue No.:PA 09 0051005

  • CAS :

    641615-50-1

  • Molecular Formula : C17H14N4O2

  • Molecular Weight : 306.33

stdClass Object
(
    [pname] => Desmethyl Imatinib D4
    [catalogue_number] => PA STI 089122
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 483.61
    [form] => C28H25D4N7O
    [cas] => NA
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PA STI 089122

Desmethyl Imatinib D4


  • Catalogue No.:PA STI 089122

  • CAS :

    NA

  • Molecular Formula : C28H25D4N7O

  • Molecular Weight : 483.61

stdClass Object
(
    [pname] => sec-Butyl 4-((4-methylpiperazin-1-yl)methyl)benzoate
    [catalogue_number] => PA 09 0051006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 290.41
    [form] => C17H26N2O2
    [cas] => NA
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PA 09 0051006

sec-Butyl 4-((4-methylpiperazin-1-yl)methyl)benzoate


  • Catalogue No.:PA 09 0051006

  • CAS :

    NA

  • Molecular Formula : C17H26N2O2

  • Molecular Weight : 290.41

stdClass Object
(
    [pname] => N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
    [catalogue_number] => PA 09 0051007
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 522.61
    [form] => C29H30N8O2
    [cas] => NA
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PA 09 0051007

N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide


  • Catalogue No.:PA 09 0051007

  • CAS :

    NA

  • Molecular Formula : C29H30N8O2

  • Molecular Weight : 522.61

stdClass Object
(
    [pname] => N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-nitrosopiperazin-1-yl)methyl)benzamide
    [catalogue_number] => PA 09 0051008
    [category_ids] => 162,70,75,76,78,82
    [chemical_name] => 
    [weight] => 508.59
    [form] => C28H28N8O2
    [cas] => 2816369-80-7
    [pslug] => 2816369-80-7-n-4-methyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-phenyl-4-4-nitrosopiperazin-1-yl-methyl-benzamide-pa090051008
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PA 09 0051008

N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-nitrosopiperazin-1-yl)methyl)benzamide


  • Catalogue No.:PA 09 0051008

  • CAS :

    2816369-80-7

  • Molecular Formula : C28H28N8O2

  • Molecular Weight : 508.59

stdClass Object
(
    [pname] => N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide
    [catalogue_number] => PA 09 0051012
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 508.59
    [form] => C28H28N8O2
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PA 09 0051012

N-(4-Methyl-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide


  • Catalogue No.:PA 09 0051012

  • CAS :

    NA

  • Molecular Formula : C28H28N8O2

  • Molecular Weight : 508.59