Nilotinib-impurities | Pharmaffiliates

nilotinib

Nilotinib is used to treat Philadelphia chromosome positive chronic myelogenous leukaemia. It is sold under the brand name Tasigna. It is not safe for use during pregnancy. Reference standards of Nilotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Nilotinib 3-Pyridinyl Impurity
    [catalogue_number] => PA 14 0641005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 172.19
    [form] => C9H8N4
    [cas] => 66521-66-2
    [pslug] => 66521-66-2-nilotinib-3-pyridinyl-impurity-pa140641005
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PA 14 0641005

Nilotinib 3-Pyridinyl Impurity


  • Catalogue No.:PA 14 0641005

  • CAS :

    66521-66-2

  • Molecular Formula : C9H8N4

  • Molecular Weight : 172.19

20% OFF
stdClass Object
(
    [pname] => Nilotinib - Impurity H (Freebase)
    [catalogue_number] => PA 14 64570
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 529.52
    [form] => C28H22F3N7O
    [cas] => 641571-15-5
    [pslug] => 641571-15-5-nilotinib-impurity-h-freebase-pa1464570
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PA 14 64570

Nilotinib - Impurity H (Freebase)


  • Catalogue No.:PA 14 64570

  • CAS :

    641571-15-5

  • Molecular Formula : C28H22F3N7O

  • Molecular Weight : 529.52

stdClass Object
(
    [pname] => 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
    [catalogue_number] => PA 14 64540
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 271.2
    [form] => C11H8F3N3O2
    [cas] => 916975-92-3
    [pslug] => 916975-92-3-4-methyl-1-3-nitro-5-trifluoromethyl-phenyl-1h-imidazole-pa1464540
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PA 14 64540

4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole


  • Catalogue No.:PA 14 64540

  • CAS :

    916975-92-3

  • Molecular Formula : C11H8F3N3O2

  • Molecular Weight : 271.2

stdClass Object
(
    [pname] => Nilotinib - Impurity H (Hydrochloride Salt)
    [catalogue_number] => PA 14 64550
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 565.98
    [form] => C28H23ClF3N7O
    [cas] => NA
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PA 14 64550

Nilotinib - Impurity H (Hydrochloride Salt)


  • Catalogue No.:PA 14 64550

  • CAS :

    NA

  • Molecular Formula : C28H23ClF3N7O

  • Molecular Weight : 565.98

stdClass Object
(
    [pname] => 3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 64560
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 563.96
    [form] => C28H21ClF3N7O
    [cas] => NA
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PA 14 64560

3-((4-Chloro-6-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 14 64560

  • CAS :

    NA

  • Molecular Formula : C28H21ClF3N7O

  • Molecular Weight : 563.96

stdClass Object
(
    [pname] => 3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride
    [catalogue_number] => PA 14 64580
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 291.7
    [form] => C12H13ClF3N3
    [cas] => NA
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PA 14 64580

3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Hydrochloride


  • Catalogue No.:PA 14 64580

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3N3

  • Molecular Weight : 291.7

stdClass Object
(
    [pname] => 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 64590
    [category_ids] => ,80,71,70,78,82,75,79,89,
    [chemical_name] => 
    [weight] => 227.19
    [form] => C10H8F3N3
    [cas] => 943320-48-7
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PA 14 64590

3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline


  • Catalogue No.:PA 14 64590

  • CAS :

    943320-48-7

  • Molecular Formula : C10H8F3N3

  • Molecular Weight : 227.19

stdClass Object
(
    [pname] => Nilotinib N-Oxide
    [catalogue_number] => PA 14 64600
    [category_ids] => 85,83,75,76,78,82,71,70,80
    [chemical_name] => 
    [weight] => 545.53
    [form] => C28H22F3N7O2
    [cas] => 1246817-85-5
    [pslug] => 1246817-85-5-nilotinib-n-oxide-pa1464600
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PA 14 64600

Nilotinib N-Oxide


  • Catalogue No.:PA 14 64600

  • CAS :

    1246817-85-5

  • Molecular Formula : C28H22F3N7O2

  • Molecular Weight : 545.53

stdClass Object
(
    [pname] => Nilotinib System Suitability Mixture
    [catalogue_number] => PA 14 0641001
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
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PA 14 0641001

Nilotinib System Suitability Mixture


  • Catalogue No.:PA 14 0641001

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] =>  3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 0641002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.37
    [form] => C19H17F3N4O
    [cas] => 915711-42-1
    [pslug] => 915711-42-1- 3-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa140641002
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PA 14 0641002

 3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 14 0641002

  • CAS :

    915711-42-1

  • Molecular Formula : C19H17F3N4O

  • Molecular Weight : 374.37

stdClass Object
(
    [pname] => 3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 0641003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 485.25
    [form] => C19H15F3IN3O
    [cas] => 926922-18-1
    [pslug] => 926922-18-1-3-iodo-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-pa140641003
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PA 14 0641003

3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 14 0641003

  • CAS :

    926922-18-1

  • Molecular Formula : C19H15F3IN3O

  • Molecular Weight : 485.25

stdClass Object
(
    [pname] => 4-(Pyridin-2-yl)pyrimidin-2-amine
    [catalogue_number] => PA 14 0641004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 172.19
    [form] => C9H8N4
    [cas] => 66521-65-1
    [pslug] => 66521-65-1-4-pyridin-2-yl-pyrimidin-2-amine-pa140641004
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PA 14 0641004

4-(Pyridin-2-yl)pyrimidin-2-amine


  • Catalogue No.:PA 14 0641004

  • CAS :

    66521-65-1

  • Molecular Formula : C9H8N4

  • Molecular Weight : 172.19

stdClass Object
(
    [pname] => 4-Methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
    [catalogue_number] => PA 14 0641006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 529.53
    [form] => C28H22F3N7O
    [cas] => 641571-05-3 
    [pslug] => 641571-05-3 -4-methyl-n-3-2-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-3-4-pyridin-3-yl-pyrimidin-2-yl-amino-benzamide-pa140641006
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PA 14 0641006

4-Methyl-N-(3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide


  • Catalogue No.:PA 14 0641006

  • CAS :

    641571-05-3 

  • Molecular Formula : C28H22F3N7O

  • Molecular Weight : 529.53

stdClass Object
(
    [pname] => Tert-butyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
    [catalogue_number] => PA 14 0641007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 362.43
    [form] => C21H22N4O2
    [cas] => 2468737-73-5
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PA 14 0641007

Tert-butyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate


  • Catalogue No.:PA 14 0641007

  • CAS :

    2468737-73-5

  • Molecular Formula : C21H22N4O2

  • Molecular Weight : 362.43

stdClass Object
(
    [pname] => N-(3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
    [catalogue_number] => PA 14 0641008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 543.55
    [form] => C29H24F3N7O
    [cas] => 2119583-25-2 
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PA 14 0641008

N-(3-(2,4-Dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide


  • Catalogue No.:PA 14 0641008

  • CAS :

    2119583-25-2 

  • Molecular Formula : C29H24F3N7O

  • Molecular Weight : 543.55

stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile
    [catalogue_number] => PA 14 0641009
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 251.21
    [form] => C12H8F3N3
    [cas] => 641571-12-2
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PA 14 0641009

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile


  • Catalogue No.:PA 14 0641009

  • CAS :

    641571-12-2

  • Molecular Formula : C12H8F3N3

  • Molecular Weight : 251.21

stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide
    [catalogue_number] => PA 14 0641010
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 269.23
    [form] => C12H10F3N3O
    [cas] => 917391-28-7
    [pslug] => 917391-28-7-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-benzamide-pa140641010
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PA 14 0641010

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide


  • Catalogue No.:PA 14 0641010

  • CAS :

    917391-28-7

  • Molecular Formula : C12H10F3N3O

  • Molecular Weight : 269.23

stdClass Object
(
    [pname] => 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic acid
    [catalogue_number] => PA 14 0641011
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 641571-13-3
    [pslug] => 641571-13-3-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-benzoic-acid-pa140641011
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PA 14 0641011

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic acid


  • Catalogue No.:PA 14 0641011

  • CAS :

    641571-13-3

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

stdClass Object
(
    [pname] => (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
    [catalogue_number] => PA 14 0641012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 176.22
    [form] => C10H12N2O
    [cas] => 123367-26-0
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PA 14 0641012

(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one


  • Catalogue No.:PA 14 0641012

  • CAS :

    123367-26-0

  • Molecular Formula : C10H12N2O

  • Molecular Weight : 176.22

stdClass Object
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    [pname] => 3-Bromo-5-nitrobenzotrifluoride
    [catalogue_number] => PA 14 0641013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 270.01
    [form] => C7H3BrF3NO2
    [cas] => 630125-49-4
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PA 14 0641013

3-Bromo-5-nitrobenzotrifluoride


  • Catalogue No.:PA 14 0641013

  • CAS :

    630125-49-4

  • Molecular Formula : C7H3BrF3NO2

  • Molecular Weight : 270.01

stdClass Object
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    [pname] => 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-nitrobenzamide
    [catalogue_number] => PA 14 0641014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 404.35
    [form] => C19H15F3N4O3
    [cas] => 1157857-29-8
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PA 14 0641014

4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-nitrobenzamide


  • Catalogue No.:PA 14 0641014

  • CAS :

    1157857-29-8

  • Molecular Formula : C19H15F3N4O3

  • Molecular Weight : 404.35

stdClass Object
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    [pname] => 2,3-Dihydroxy-4-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-oxobutanoic acid
    [catalogue_number] => PA 14 0641015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 661.6
    [form] => C32H26F3N7O6
    [cas] => NA
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PA 14 0641015

2,3-Dihydroxy-4-((2-methyl-5-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamoyl)phenyl)(4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-oxobutanoic acid


  • Catalogue No.:PA 14 0641015

  • CAS :

    NA

  • Molecular Formula : C32H26F3N7O6

  • Molecular Weight : 661.6

stdClass Object
(
    [pname] => 3-Guanidino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
    [catalogue_number] => PA 14 0641016
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 416.41
    [form] => C20H19F3N6O
    [cas] => 1345336-53-9
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PA 14 0641016

3-Guanidino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 14 0641016

  • CAS :

    1345336-53-9

  • Molecular Formula : C20H19F3N6O

  • Molecular Weight : 416.41

stdClass Object
(
    [pname] => tert-Butyl (3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamate
    [catalogue_number] => PA 14 0641018
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 341.33
    [form] => C16H18F3N3O2
    [cas] => 641571-14-4
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PA 14 0641018

tert-Butyl (3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)carbamate


  • Catalogue No.:PA 14 0641018

  • CAS :

    641571-14-4

  • Molecular Formula : C16H18F3N3O2

  • Molecular Weight : 341.33

stdClass Object
(
    [pname] => 3,5-Dinitrobenzotrifluoride
    [catalogue_number] => PA 14 0641017
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 236.11
    [form] => C7H3F3N2O4
    [cas] => 401-99-0
    [pslug] => 401-99-0-3-5-dinitrobenzotrifluoride-pa140641017
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PA 14 0641017

3,5-Dinitrobenzotrifluoride


  • Catalogue No.:PA 14 0641017

  • CAS :

    401-99-0

  • Molecular Formula : C7H3F3N2O4

  • Molecular Weight : 236.11

stdClass Object
(
    [pname] => Sodium 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
    [catalogue_number] => PA 14 0641019
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 328.31
    [form] => C17H13N4NaO2
    [cas] => 1207060-52-3
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PA 14 0641019

Sodium 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate


  • Catalogue No.:PA 14 0641019

  • CAS :

    1207060-52-3

  • Molecular Formula : C17H13N4NaO2

  • Molecular Weight : 328.31

stdClass Object
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    [pname] => 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
    [catalogue_number] => PA 14 0641020
    [category_ids] => ,162,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 558.53
    [form] => C28H21F3N8O2
    [cas] => 2925306-68-7
    [pslug] => 2925306-68-7-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-3-nitroso-4-pyridin-3-yl-pyrimidin-2-yl-amino-benzamide-pa140641020
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PA 14 0641020

4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(nitroso(4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide


  • Catalogue No.:PA 14 0641020

  • CAS :

    2925306-68-7

  • Molecular Formula : C28H21F3N8O2

  • Molecular Weight : 558.53

stdClass Object
(
    [pname] => 4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3,5-bis((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride
    [catalogue_number] => PA 14 0641021
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 736.16
    [form] => C37H29ClF3N11O
    [cas] => NA
    [pslug] => 4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-3-5-bis-4-pyridin-3-yl-pyrimidin-2-yl-amino-benzamide-hydrochloride-pa140641021
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PA 14 0641021

4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3,5-bis((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide Hydrochloride


  • Catalogue No.:PA 14 0641021

  • CAS :

    NA

  • Molecular Formula : C37H29ClF3N11O

  • Molecular Weight : 736.16

stdClass Object
(
    [pname] => 3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide Hydrochloride
    [catalogue_number] => PA 14 0641022
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 410.83
    [form] => C19H18ClF3N4O
    [cas] => 2322358-68-7
    [pslug] => 2322358-68-7-3-amino-4-methyl-n-3-4-methyl-1h-imidazol-1-yl-5-trifluoromethyl-phenyl-benzamide-hydrochloride-pa140641022
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PA 14 0641022

3-Amino-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide Hydrochloride


  • Catalogue No.:PA 14 0641022

  • CAS :

    2322358-68-7

  • Molecular Formula : C19H18ClF3N4O

  • Molecular Weight : 410.83

stdClass Object
(
    [pname] => 3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
    [catalogue_number] => PA 14 0641023
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 241.22
    [form] => C11H10F3N3
    [cas] => 641571-06-4
    [pslug] => 641571-06-4-3-2-methyl-1h-imidazol-1-yl-5-trifluoromethyl-aniline-pa140641023
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PA 14 0641023

3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline


  • Catalogue No.:PA 14 0641023

  • CAS :

    641571-06-4

  • Molecular Formula : C11H10F3N3

  • Molecular Weight : 241.22

stdClass Object
(
    [pname] => Nilotinib Imidazolyl N-oxide
    [catalogue_number] => PA 14 0641025
    [category_ids] => ,75,78,70,82,
    [chemical_name] => 
    [weight] => 545.53
    [form] => C28H22F3N7O2
    [cas] => 2139382-75-3
    [pslug] => 2139382-75-3-nilotinib-imidazolyl-n-oxide-pa140641025
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PA 14 0641025

Nilotinib Imidazolyl N-oxide


  • Catalogue No.:PA 14 0641025

  • CAS :

    2139382-75-3

  • Molecular Formula : C28H22F3N7O2

  • Molecular Weight : 545.53