Spironolactone-Impurities | Pharmaffiliates

spironolactone

Spironolactone is used for the treatment of heart failures and kidney diseases. It is metabolised in liver and major metabolites of spironolactone are 7α-TMS,6β-OH-7α-TMS and canrenone,. Reference standards of Spironolactone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
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    [pname] => Spironolactone - Impurity A
    [catalogue_number] => PA 19 18010
    [category_ids] => ,69,75,78,70,82,87,
    [chemical_name] => 
    [weight] => 414.56
    [form] => C24H30O4S
    [cas] => 132458-33-4
    [pslug] => 132458-33-4-spironolactone-impurity-a-pa1918010
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PA 19 18010

Spironolactone - Impurity A


  • Catalogue No.:PA 19 18010

  • CAS :

    132458-33-4

  • Molecular Formula : C24H30O4S

  • Molecular Weight : 414.56

stdClass Object
(
    [pname] => 7α-Thiomethyl Spironolactone-d7 (Major)
    [catalogue_number] => PA STI 082790
    [category_ids] => ,76,75,78,70,82,87,98,
    [chemical_name] => 
    [weight] => 395.61
    [form] => C23H25D7O3S
    [cas] => NA
    [pslug] => 7-alpha-thiomethyl-spironolactone-d7-major-pasti082790
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PA STI 082790

7α-Thiomethyl Spironolactone-d7 (Major)


  • Catalogue No.:PA STI 082790

  • CAS :

    NA

  • Molecular Formula : C23H25D7O3S

  • Molecular Weight : 395.61

stdClass Object
(
    [pname] => Spironolactone - Impurity B
    [catalogue_number] => PA 19 18020
    [category_ids] => ,80,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 495.47
    [form] => C24H31BrO4S
    [cas] => NA
    [pslug] => spironolactone-impurity-b-pa1918020
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PA 19 18020

Spironolactone - Impurity B


  • Catalogue No.:PA 19 18020

  • CAS :

    NA

  • Molecular Formula : C24H31BrO4S

  • Molecular Weight : 495.47

stdClass Object
(
    [pname] => Spironolactone - Impurity G
    [catalogue_number] => PA 19 18070
    [category_ids] => ,80,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 432.58
    [form] => C24H32O5S
    [cas] => 880106-10-5
    [pslug] => 880106-10-5-spironolactone-impurity-g-pa1918070
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PA 19 18070

Spironolactone - Impurity G


  • Catalogue No.:PA 19 18070

  • CAS :

    880106-10-5

  • Molecular Formula : C24H32O5S

  • Molecular Weight : 432.58

stdClass Object
(
    [pname] => Spironolactone - Impurity H
    [catalogue_number] => PA 19 18080
    [category_ids] => ,80,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 298.43
    [form] => C20H26O2
    [cas] => 53866-24-3
    [pslug] => 53866-24-3-spironolactone-impurity-h-pa1918080
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PA 19 18080

Spironolactone - Impurity H


  • Catalogue No.:PA 19 18080

  • CAS :

    53866-24-3

  • Molecular Formula : C20H26O2

  • Molecular Weight : 298.43

stdClass Object
(
    [pname] => (8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
    [catalogue_number] => PAI 19 018001
    [category_ids] => ,78,70,75,76,82,
    [chemical_name] => 
    [weight] => 342.48
    [form] => C22H30O3
    [cas] => NA
    [pslug] => -8r-9s-10r-13s-14s-17s-17-hydroxy-17-3-hydroxyprop-1-yn-1-yl-10-13-dimethyl-1-2-6-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-3h-cyclopenta-a-phenanthren-3-one-pai19018001
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PAI 19 018001

(8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one


  • Catalogue No.:PAI 19 018001

  • CAS :

    NA

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

stdClass Object
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    [pname] => (8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
    [catalogue_number] => PAI 19 018002
    [category_ids] => ,78,70,75,76,82,
    [chemical_name] => 
    [weight] => 344.5
    [form] => C22H32O3
    [cas] => NA
    [pslug] => -8r-9s-10r-13s-14s-17r-17-hydroxy-17-3-hydroxyprop-1-en-1-yl-10-13-dimethyl-1-2-6-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-3h-cyclopenta-a-phenanthren-3-one-pai19018002
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PAI 19 018002

(8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one


  • Catalogue No.:PAI 19 018002

  • CAS :

    NA

  • Molecular Formula : C22H32O3

  • Molecular Weight : 344.5

stdClass Object
(
    [pname] => (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione
    [catalogue_number] => PAI 19 018003
    [category_ids] => ,78,70,75,76,82,
    [chemical_name] => 
    [weight] => 340.46
    [form] => C22H28O3
    [cas] => 52845-59-7
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PAI 19 018003

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione


  • Catalogue No.:PAI 19 018003

  • CAS :

    52845-59-7

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

stdClass Object
(
    [pname] => (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione
    [catalogue_number] => PAI 19 018004
    [category_ids] => ,78,70,75,76,82,
    [chemical_name] => 
    [weight] => 338.45
    [form] => C22H26O3
    [cas] => NA
    [pslug] => -8r-9s-10r-13s-14s-17r-10-13-dimethyl-1-8-9-10-11-12-13-14-15-16-decahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-3-5-2h-dione-pai19018004
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PAI 19 018004

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione


  • Catalogue No.:PAI 19 018004

  • CAS :

    NA

  • Molecular Formula : C22H26O3

  • Molecular Weight : 338.45

stdClass Object
(
    [pname] => Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate
    [catalogue_number] => PAI 19 018005
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 386.53
    [form] => C24H34O4
    [cas] => NA
    [pslug] => -ethyl-3-3s-8r-9s-10r-13s-14s-17s-3-17-dihydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-propiolate-pai19018005
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PAI 19 018005

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate


  • Catalogue No.:PAI 19 018005

  • CAS :

    NA

  • Molecular Formula : C24H34O4

  • Molecular Weight : 386.53

stdClass Object
(
    [pname] => Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate
    [catalogue_number] => PAI 19 018006
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    [chemical_name] => 
    [weight] => 388.55
    [form] => C24H36O4
    [cas] => NA
    [pslug] => -ethyl-e-3-3s-8r-9s-10r-13s-14s-17r-3-17-dihydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-acrylate-pai19018006
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PAI 19 018006

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate


  • Catalogue No.:PAI 19 018006

  • CAS :

    NA

  • Molecular Formula : C24H36O4

  • Molecular Weight : 388.55

stdClass Object
(
    [pname] => (3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one
    [catalogue_number] => PAI 19 018007
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 342.48
    [form] => C22H30O3
    [cas] => NA
    [pslug] => -3s-8r-9s-10r-13s-14s-17r-3-hydroxy-10-13-dimethyl-1-2-3-4-7-8-9-10-11-12-13-14-15-16-tetradecahydro-5h-spiro-cyclopenta-a-phenanthrene-17-2-furan-5-one-pai19018007
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PAI 19 018007

(3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one


  • Catalogue No.:PAI 19 018007

  • CAS :

    NA

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

stdClass Object
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    [pname] => (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one
    [catalogue_number] => PAI 19 018008
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 402.69
    [form] => C25H42O2Si
    [cas] => 42151-23-5
    [pslug] => 42151-23-5-3beta-3-1-1-dimethylethyl-dimethylsilyl-oxy-androst-5-en-17-one-pai19018008
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PAI 19 018008

(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one


  • Catalogue No.:PAI 19 018008

  • CAS :

    42151-23-5

  • Molecular Formula : C25H42O2Si

  • Molecular Weight : 402.69

stdClass Object
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    [pname] => Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate
    [catalogue_number] => PAI 19 018009
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    [chemical_name] => 
    [weight] => 500.8
    [form] => C30H48O4Si
    [cas] => NA
    [pslug] => -ethyl-3-3s-8r-9s-10r-13s-14s-17s-3-tert-butyldimethylsilyl-oxy-17-hydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-propiolate-pai19018009
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PAI 19 018009

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate


  • Catalogue No.:PAI 19 018009

  • CAS :

    NA

  • Molecular Formula : C30H48O4Si

  • Molecular Weight : 500.8

stdClass Object
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    [pname] => Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate
    [catalogue_number] => PAI 19 018010
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 502.81
    [form] => C30H50O4Si
    [cas] => NA
    [pslug] => -ethyl-e-3-3s-8r-9s-10r-13s-14s-17r-3-tert-butyldimethylsilyl-oxy-17-hydroxy-10-13-dimethyl-2-3-4-7-8-9-10-11-12-13-14-15-16-17-tetradecahydro-1h-cyclopenta-a-phenanthren-17-yl-acrylate-pai19018010
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PAI 19 018010

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate


  • Catalogue No.:PAI 19 018010

  • CAS :

    NA

  • Molecular Formula : C30H50O4Si

  • Molecular Weight : 502.81

stdClass Object
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    [pname] => (3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one
    [catalogue_number] => PAI 19 018011
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 456.74
    [form] => C28H44O3Si
    [cas] => NA
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PAI 19 018011

(3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one


  • Catalogue No.:PAI 19 018011

  • CAS :

    NA

  • Molecular Formula : C28H44O3Si

  • Molecular Weight : 456.74

stdClass Object
(
    [pname] => 7α-Thiomethyl spironolactone
    [catalogue_number] => PA 19 0181000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 388.57
    [form] => C23H32O3S
    [cas] => 38753-77-4
    [pslug] => 38753-77-4-7alpha-thiomethyl-spironolactone-pa190181000
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PA 19 0181000

7α-Thiomethyl spironolactone


  • Catalogue No.:PA 19 0181000

  • CAS :

    38753-77-4

  • Molecular Formula : C23H32O3S

  • Molecular Weight : 388.57

stdClass Object
(
    [pname] => 7α-Thio spironolactone
    [catalogue_number] => PA 19 0181001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.54
    [form] => C22H30O3S
    [cas] => 38753-76-3
    [pslug] => 38753-76-3-7alpha-thio-spironolactone-pa190181001
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PA 19 0181001

7α-Thio spironolactone


  • Catalogue No.:PA 19 0181001

  • CAS :

    38753-76-3

  • Molecular Formula : C22H30O3S

  • Molecular Weight : 374.54

stdClass Object
(
    [pname] => Spironolactone (IPRS/36/18)-from IPC
    [catalogue_number] => PA IPRS 36 18
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
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Spironolactone (IPRS/36/18)-from IPC


  • Catalogue No.:PA IPRS 36 18

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA