Dabrafenib-impurities | Pharmaffiliates

dabrafenib

Dabrafenib is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It is used alone or in combination with another medication to treat a type of skin cancer.. Reference standards of Dabrafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

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    [pname] => Dabrafenib - API Standards 
    [catalogue_number] => PA 31 06000
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 519.56
    [form] => C23H20F3N5O2S2
    [cas] => 1195765-45-7
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PA 31 06000

Dabrafenib - API Standards


  • Catalogue No.:PA 31 06000

  • CAS :

    1195765-45-7

  • Molecular Formula : C23H20F3N5O2S2

  • Molecular Weight : 519.56

stdClass Object
(
    [pname] => 2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide
    [catalogue_number] => PA 31 0061000
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 516.59
    [form] => C23H22F2N6O2S2
    [cas] => 2017554-98-0
    [pslug] => 2017554-98-0-2-amino-n-3-5-2-aminopyrimidin-4-yl-2-tert-butyl-thiazol-4-yl-2-fluorophenyl-6-fluorobenzenesulfonamide-pa310061000
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PA 31 0061000

2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide


  • Catalogue No.:PA 31 0061000

  • CAS :

    2017554-98-0

  • Molecular Formula : C23H22F2N6O2S2

  • Molecular Weight : 516.59

stdClass Object
(
    [pname] => Carboxy Dabrafenib
    [catalogue_number] => PA 31 0061001
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 549.54
    [form] => C23H18F3N5O4S2
    [cas] => 1195873-54-1
    [pslug] => 1195873-54-1-carboxy-dabrafenib-pa310061001
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PA 31 0061001

Carboxy Dabrafenib


  • Catalogue No.:PA 31 0061001

  • CAS :

    1195873-54-1

  • Molecular Formula : C23H18F3N5O4S2

  • Molecular Weight : 549.54

stdClass Object
(
    [pname] => Hydroxy Dabrafenib
    [catalogue_number] => PA 31 0061002
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 535.56
    [form] => C23H20F3N5O3S2
    [cas] => 1195767-77-1
    [pslug] => 1195767-77-1-hydroxy-dabrafenib-pa310061002
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PA 31 0061002

Hydroxy Dabrafenib


  • Catalogue No.:PA 31 0061002

  • CAS :

    1195767-77-1

  • Molecular Formula : C23H20F3N5O3S2

  • Molecular Weight : 535.56

stdClass Object
(
    [pname] => Desmethyl Dabrafenib
    [catalogue_number] => PA 31 0061003
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 505.53
    [form] => C22H18F3N5O2S2
    [cas] => 1195765-47-9
    [pslug] => 1195765-47-9-desmethyl-dabrafenib-pa310061003
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PA 31 0061003

Desmethyl Dabrafenib


  • Catalogue No.:PA 31 0061003

  • CAS :

    1195765-47-9

  • Molecular Formula : C22H18F3N5O2S2

  • Molecular Weight : 505.53

stdClass Object
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    [pname] => 2,4-Difluorobenzenesulfonyl Chloride
    [catalogue_number] => PA 31 0061004
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 212.59
    [form] => C6H3ClF2O2S
    [cas] => 13918-92-8
    [pslug] => 13918-92-8-2-4-difluorobenzenesulfonyl-chloride-pa310061004
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PA 31 0061004

2,4-Difluorobenzenesulfonyl Chloride


  • Catalogue No.:PA 31 0061004

  • CAS :

    13918-92-8

  • Molecular Formula : C6H3ClF2O2S

  • Molecular Weight : 212.59

stdClass Object
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    [pname] => 4-Bromo-2-fluorobenzenesulfonyl Chloride
    [catalogue_number] => PA 31 0061005
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 273.5
    [form] => C6H3BrClFO2S
    [cas] => 216159-03-4
    [pslug] => 216159-03-4-4-bromo-2-fluorobenzenesulfonyl-chloride-pa310061005
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PA 31 0061005

4-Bromo-2-fluorobenzenesulfonyl Chloride


  • Catalogue No.:PA 31 0061005

  • CAS :

    216159-03-4

  • Molecular Formula : C6H3BrClFO2S

  • Molecular Weight : 273.5

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    [pname] => 2,4,6-Trifluorobenzene-1-sulfonyl Chloride
    [catalogue_number] => PA 31 0061006
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    [chemical_name] => 
    [weight] => 230.59
    [form] => C6H2ClF3O2S
    [cas] => 220239-64-5
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PA 31 0061006

2,4,6-Trifluorobenzene-1-sulfonyl Chloride


  • Catalogue No.:PA 31 0061006

  • CAS :

    220239-64-5

  • Molecular Formula : C6H2ClF3O2S

  • Molecular Weight : 230.59

stdClass Object
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    [pname] => 2-Fluoro-6-methoxybenzenesulphonyl Chloride
    [catalogue_number] => PA 31 0061007
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 224.63
    [form] => C7H6ClFO3S
    [cas] => 1176126-31-0
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PA 31 0061007

2-Fluoro-6-methoxybenzenesulphonyl Chloride


  • Catalogue No.:PA 31 0061007

  • CAS :

    1176126-31-0

  • Molecular Formula : C7H6ClFO3S

  • Molecular Weight : 224.63

stdClass Object
(
    [pname] => Methyl 3-amino-4-fluorobenzoate
    [catalogue_number] => PA 31 0061008
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 169.16
    [form] => C8H8FNO2
    [cas] => 369-26-6
    [pslug] => 369-26-6-methyl-3-amino-4-fluorobenzoate-pa310061008
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PA 31 0061008

Methyl 3-amino-4-fluorobenzoate


  • Catalogue No.:PA 31 0061008

  • CAS :

    369-26-6

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

stdClass Object
(
    [pname] => Methyl 3-amino-5-fluorobenzoate
    [catalogue_number] => PA 31 0061009
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 169.16
    [form] => C8H8FNO2
    [cas] => 884497-46-5
    [pslug] => 884497-46-5-methyl-3-amino-5-fluorobenzoate-pa310061009
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PA 31 0061009

Methyl 3-amino-5-fluorobenzoate


  • Catalogue No.:PA 31 0061009

  • CAS :

    884497-46-5

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

stdClass Object
(
    [pname] => Methyl 5-amino-2-fluorobenzoate
    [catalogue_number] => PA 31 0061010
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 169.16
    [form] => C8H8FNO2
    [cas] => 56741-34-5
    [pslug] => 56741-34-5-methyl-5-amino-2-fluorobenzoate-pa310061010
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PA 31 0061010

Methyl 5-amino-2-fluorobenzoate


  • Catalogue No.:PA 31 0061010

  • CAS :

    56741-34-5

  • Molecular Formula : C8H8FNO2

  • Molecular Weight : 169.16

stdClass Object
(
    [pname] => 3-Amino-2-fluorobenzoic Acid
    [catalogue_number] => PA 31 0061011
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 155.13
    [form] => C7H6FNO2
    [cas] => 914223-43-1
    [pslug] => 914223-43-1-3-amino-2-fluorobenzoic-acid-pa310061011
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PA 31 0061011

3-Amino-2-fluorobenzoic Acid


  • Catalogue No.:PA 31 0061011

  • CAS :

    914223-43-1

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

stdClass Object
(
    [pname] => N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2-fluoro-6-methoxybenzenesulfonamide
    [catalogue_number] => PA 31 0061012
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 531.6
    [form] => C24H23F2N5O3S2
    [cas] => NA
    [pslug] => n-3-5-2-aminopyrimidin-4-yl-2-tert-butyl-thiazol-4-yl-2-fluorophenyl-2-fluoro-6-methoxybenzenesulfonamide-pa310061012
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PA 31 0061012

N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2-fluoro-6-methoxybenzenesulfonamide


  • Catalogue No.:PA 31 0061012

  • CAS :

    NA

  • Molecular Formula : C24H23F2N5O3S2

  • Molecular Weight : 531.6

stdClass Object
(
    [pname] => 2-Fluoro-6-nitrobenzenesulfonyl Chloride
    [catalogue_number] => PA 31 0061013
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 239.6
    [form] => C6H3ClFNO4S
    [cas] => 887266-98-0
    [pslug] => 887266-98-0-2-fluoro-6-nitrobenzenesulfonyl-chloride-pa310061013
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PA 31 0061013

2-Fluoro-6-nitrobenzenesulfonyl Chloride


  • Catalogue No.:PA 31 0061013

  • CAS :

    887266-98-0

  • Molecular Formula : C6H3ClFNO4S

  • Molecular Weight : 239.6

stdClass Object
(
    [pname] => Methyl 3-amino-2-methoxybenzoate
    [catalogue_number] => PA 31 0061014
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 181.19
    [form] => C9H11NO3
    [cas] => 5129-25-9
    [pslug] => 5129-25-9-methyl-3-amino-2-methoxybenzoate-pa310061014
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PA 31 0061014

Methyl 3-amino-2-methoxybenzoate


  • Catalogue No.:PA 31 0061014

  • CAS :

    5129-25-9

  • Molecular Formula : C9H11NO3

  • Molecular Weight : 181.19

stdClass Object
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    [pname] => M30-Dabrafenib
    [catalogue_number] => PA 31 0061017
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 551.52
    [form] => C22H16F3N5O5S2
    [cas] => 1613724-38-1
    [pslug] => 1613724-38-1-m30-dabrafenib-pa310061017
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PA 31 0061017

M30-Dabrafenib


  • Catalogue No.:PA 31 0061017

  • CAS :

    1613724-38-1

  • Molecular Formula : C22H16F3N5O5S2

  • Molecular Weight : 551.52

stdClass Object
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    [pname] => M31-Dabrafenib
    [catalogue_number] => PA 31 0061018
    [category_ids] => ,79,80,71,78,70,82,89,88,
    [chemical_name] => 
    [weight] => 503.52
    [form] => C22H16F3N5O2S2
    [cas] => 1613724-51-8
    [pslug] => 1613724-51-8-m31-dabrafenib-pa310061018
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PA 31 0061018

M31-Dabrafenib


  • Catalogue No.:PA 31 0061018

  • CAS :

    1613724-51-8

  • Molecular Formula : C22H16F3N5O2S2

  • Molecular Weight : 503.52

stdClass Object
(
    [pname] => Dabrafenib Glucuronide
    [catalogue_number] => PA 31 0061019
    [category_ids] => ,79,80,71,78,70,82,89,88,95,
    [chemical_name] => 
    [weight] => 695.64
    [form] => C28H24F3N5O9S2
    [cas] => 2147682-66-2
    [pslug] => 2147682-66-2-dabrafenib-glucuronide-pa310061019
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PA 31 0061019

Dabrafenib Glucuronide


  • Catalogue No.:PA 31 0061019

  • CAS :

    2147682-66-2

  • Molecular Formula : C28H24F3N5O9S2

  • Molecular Weight : 695.64