A selective and reversible inhibitor of enzyme catechol-O-methyltransferase (COMT), it is used for the treatment of Parkinson's disease. It is used in addition to levodopa. Reference standards of Entacapone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Entacapone - API Standards [catalogue_number] => PA 05 06000 [category_ids] => ,70,78,82, [chemical_name] => [weight] => 305.29 [form] => C14H15N3O5 [cas] => 130929-57-6 [pslug] => 130929-57-6-entacapone-api-pa0506000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06000
CAS :
Molecular Formula : C14H15N3O5
Molecular Weight : 305.29
stdClass Object ( [pname] => Entacapone - Impurity A [catalogue_number] => PA 05 06010 [category_ids] => ,70,78,82, [chemical_name] => [weight] => 305.29 [form] => C14H15N3O5 [cas] => 145195-63-7 [pslug] => 145195-63-7-entacapone-impurity-a-pa0506010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06010
stdClass Object ( [pname] => Entacapone - Impurity B [catalogue_number] => PA 05 06020 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 278.22 [form] => C12H10N2O6 [cas] => 1215039-66-9 [pslug] => 1215039-66-9-entacapone-impurity-b-pa0506020 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06020
Molecular Formula : C12H10N2O6
Molecular Weight : 278.22
stdClass Object ( [pname] => Entacapone - Impurity C [catalogue_number] => PA 05 06030 [category_ids] => ,80,75,78,70,82, [chemical_name] => [weight] => 183.12 [form] => C7H5NO5 [cas] => 116313-85-0 [pslug] => 116313-85-0-entacapone-impurity-c-pa0506030 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06030
Molecular Formula : C7H5NO5
Molecular Weight : 183.12
stdClass Object ( [pname] => Entacapone - Impurity D [catalogue_number] => PA 05 06040 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 333.34 [form] => C16H19N3O5 [cas] => 857629-79-9 [pslug] => 857629-79-9-entacapone-impurity-d-pa0506040 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06040
Molecular Formula : C16H19N3O5
Molecular Weight : 333.34
stdClass Object ( [pname] => Entacapone - Impurity E [catalogue_number] => PA 05 06050 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 200.11 [form] => C6H4N2O6 [cas] => 7659-29-2 [pslug] => 7659-29-2-entacapone-impurity-e-pa0506050 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06050
Molecular Formula : C6H4N2O6
Molecular Weight : 200.11
stdClass Object ( [pname] => Entacapone - Impurity F [catalogue_number] => PA 05 06060 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 250.16 [form] => C10H6N2O6 [cas] => 160391-70-8 [pslug] => 160391-70-8-entacapone-impurity-f-pa0506060 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06060
Molecular Formula : C10H6N2O6
Molecular Weight : 250.16
stdClass Object ( [pname] => Entacapone - Impurity G [catalogue_number] => PA 05 06070 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 263.21 [form] => C11H9N3O5 [cas] => 1364322-41-7 [pslug] => 1364322-41-7-entacapone-impurity-g-pa0506070 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06070
Molecular Formula : C11H9N3O5
Molecular Weight : 263.21
stdClass Object ( [pname] => Entacapone - Impurity H [catalogue_number] => PA 05 06080 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 317.30 [form] => C15H15N3O5 [cas] => 1150310-15-8 [pslug] => 1150310-15-8-entacapone-impurity-h-pa0506080 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06080
Molecular Formula : C15H15N3O5
Molecular Weight : 317.30
stdClass Object ( [pname] => (E)-2-Cyano-3-(3,4-dihydroxy-2-nitrophenyl)-N,N-diethylacrylamide [catalogue_number] => PA 05 06510 [category_ids] => ,78,70,82,80, [chemical_name] => [weight] => 305.29 [form] => C14H15N3O5 [cas] => NA [pslug] => e-2-cyano-3-3-4-dihydroxy-2-nitrophenyl-n-n-diethylacrylamide-pa0506510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06510
stdClass Object ( [pname] => Entacapone Vanillin Dimer [catalogue_number] => PA 05 06520 [category_ids] => ,78,70,82,80, [chemical_name] => [weight] => 400.47 [form] => C21H28N4O4 [cas] => 2518048-68-3 [pslug] => 2518048-68-3-entacapone-vanillin-dimer-pa0506520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06520
Molecular Formula : C21H28N4O4
Molecular Weight : 400.47
stdClass Object ( [pname] => 5-Nitrovanillin Dimer Impurity [catalogue_number] => PA 05 06530 [category_ids] => ,78,70,82,80, [chemical_name] => [weight] => 459.5 [form] => C22H29N5O6 [cas] => 2514697-83-5 [pslug] => 2514697-83-5-5-nitrovanillin-dimer-impurity-pa0506530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06530
Molecular Formula : C22H29N5O6
Molecular Weight : 459.5
stdClass Object ( [pname] => cis-Entacapone-d10 [catalogue_number] => PA STI 037060 [category_ids] => ,78,70,82,98, [chemical_name] => [weight] => 315.35 [form] => C14H5D10N3O5 [cas] => 1185241-19-3 [pslug] => 1185241-19-3-cis-entacapone-d10-pasti037060 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 037060
Molecular Formula : C14H5D10N3O5
Molecular Weight : 315.35
stdClass Object ( [pname] => E-Entacapone-d10 [catalogue_number] => PA STI 037070 [category_ids] => ,78,70,82,98, [chemical_name] => [weight] => 315.35 [form] => C14H5D10N3O5 [cas] => NA [pslug] => e-entacapone-d10-pasti037070 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 037070
stdClass Object ( [pname] => 2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide [catalogue_number] => PA 05 06540 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 249.18 [form] => C10H7N3O5 [cas] => 158693-01-7 [pslug] => 158693-01-7-2-cyano-3-3-4-dihydroxy-5-nitrophenyl-acrylamide-pa0506540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 06540
Molecular Formula : C10H7N3O5
Molecular Weight : 249.18
stdClass Object ( [pname] => Entacapone 3-o-glucuronide [catalogue_number] => PA 05 0061000 [category_ids] => ,70,75,76,78,82,95, [chemical_name] => [weight] => 481.41 [form] => C20H23N3O11 [cas] => 158069-75-1 [pslug] => 158069-75-1-entacapone-3-o-glucuronide-pa050061000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061000
Molecular Formula : C20H23N3O11
Molecular Weight : 481.41
stdClass Object ( [pname] => 3,4-Dihydroxy-5-nitrobenzoic acid [catalogue_number] => PA 05 0061001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 199.12 [form] => C7H5NO6 [cas] => 84211-30-3 [pslug] => 84211-30-3-3-4-dihydroxy-5-nitrobenzoic-acid-pa050061001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061001
Molecular Formula : C7H5NO6
Molecular Weight : 199.12
stdClass Object ( [pname] => (E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylic acid [catalogue_number] => PA 05 0061002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 264.19 [form] => C11H8N2O6 [cas] => 1202160-40-4 [pslug] => 1202160-40-4-e-2-cyano-3-4-hydroxy-3-methoxy-5-nitrophenyl-acrylic-acid-pa050061002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061002
Molecular Formula : C11H8N2O6
Molecular Weight : 264.19
stdClass Object ( [pname] => (E)-3-O-Methyl Entacapone [catalogue_number] => PA 05 0061003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 319.32 [form] => C15H17N3O5 [cas] => 857629-78-8 [pslug] => 857629-78-8-e-3-o-methyl-entacapone-pa050061003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061003
Molecular Formula : C15H17N3O5
Molecular Weight : 319.32
stdClass Object ( [pname] => (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-ethylacrylamide [catalogue_number] => PA 05 0061004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 277.24 [form] => C12H11N3O5 [cas] => 150995-46-3 [pslug] => 150995-46-3-e-2-cyano-3-3-4-dihydroxy-5-nitrophenyl-n-ethylacrylamide-pa050061004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061004
Molecular Formula : C12H11N3O5
Molecular Weight : 277.24
stdClass Object ( [pname] => (E/Z)-3-O-Methyl Entacapone [catalogue_number] => PA 05 0061005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 319.32 [form] => C15H17N3O5 [cas] => 146698-91-1 [pslug] => 146698-91-1-e-z-3-o-methyl-entacapone-pa050061005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061005
stdClass Object ( [pname] => N,N-Diethyl-2-hydroxyacetamide [catalogue_number] => PA 05 0061006 [category_ids] => ,76,78,70,82, [chemical_name] => [weight] => 131.18 [form] => C6H13NO2 [cas] => 39096-01-0 [pslug] => 39096-01-0-n-n-diethyl-2-hydroxyacetamide-pa050061006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 05 0061006
Molecular Formula : C6H13NO2
Molecular Weight : 131.18
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