Levosimendan-impurities | Pharmaffiliates

levosimendan

Levosimendan is marketed under the trade name Simdax. It is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. Reference standards of Levosimendan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Levosimendan - API Standards 
    [catalogue_number] => PA 12 42000
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 280.28
    [form] => C14H12N6O
    [cas] => 141505-33-1
    [pslug] => 141505-33-1-levosimendan-api-pa1242000
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PA 12 42000

Levosimendan - API Standards


  • Catalogue No.:PA 12 42000

  • CAS :

    141505-33-1

  • Molecular Formula : C14H12N6O

  • Molecular Weight : 280.28

stdClass Object
(
    [pname] => 2-[2-[4-(2-Azidotetrahydro-3-methyl-5-oxo-2-furanyl)phenyl]hydrazinylidene]propanedinitrile
    [catalogue_number] => PA 12 42510
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 309.28
    [form] => C14H11N7O2
    [cas] => 252638-01-0
    [pslug] => 252638-01-0-2-2-4-2-azidotetrahydro-3-methyl-5-oxo-2-furanyl-phenyl-hydrazinylidene-propanedinitrile-pa1242510
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PA 12 42510

2-[2-[4-(2-Azidotetrahydro-3-methyl-5-oxo-2-furanyl)phenyl]hydrazinylidene]propanedinitrile


  • Catalogue No.:PA 12 42510

  • CAS :

    252638-01-0

  • Molecular Formula : C14H11N7O2

  • Molecular Weight : 309.28

stdClass Object
(
    [pname] => Levosimendan Cyanoacetate Hydrazone Impurity
    [catalogue_number] => PA 12 42520
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 327.34
    [form] => C16H17N5O3
    [cas] => NA
    [pslug] => levosimendan-cyanoacetate-hydrazone-impurity-pa1242520
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PA 12 42520

Levosimendan Cyanoacetate Hydrazone Impurity


  • Catalogue No.:PA 12 42520

  • CAS :

    NA

  • Molecular Formula : C16H17N5O3

  • Molecular Weight : 327.34

stdClass Object
(
    [pname] => (4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide
    [catalogue_number] => PA 12 42540
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 280.28
    [form] => C14H12N6O
    [cas] => 131741-08-7
    [pslug] => 131741-08-7-4-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-carbonohydrazonoyl-dicyanide-pa1242540
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PA 12 42540

(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide


  • Catalogue No.:PA 12 42540

  • CAS :

    131741-08-7

  • Molecular Formula : C14H12N6O

  • Molecular Weight : 280.28

stdClass Object
(
    [pname] => Levosimendan Cyanoacetamide Hydrazone Impurity
    [catalogue_number] => PA 12 42550
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 298.31
    [form] => C14H14N6O2
    [cas] => 274263-65-9
    [pslug] => 274263-65-9-levosimendan-cyanoacetamide-hydrazone-impurity-pa1242550
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PA 12 42550

Levosimendan Cyanoacetamide Hydrazone Impurity


  • Catalogue No.:PA 12 42550

  • CAS :

    274263-65-9

  • Molecular Formula : C14H14N6O2

  • Molecular Weight : 298.31

stdClass Object
(
    [pname] => 6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
    [catalogue_number] => PA 12 42570
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 203.25
    [form] => C11H13N3O
    [cas] => 36725-28-7
    [pslug] => 36725-28-7-6-4-aminophenyl-5-methyl-4-5-dihydropyridazin-3-2h-one-pa1242570
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PA 12 42570

6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one


  • Catalogue No.:PA 12 42570

  • CAS :

    36725-28-7

  • Molecular Formula : C11H13N3O

  • Molecular Weight : 203.25

stdClass Object
(
    [pname] => 2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl Cyanide
    [catalogue_number] => PA 12 42580
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 298.31
    [form] => C14H14N6O2
    [cas] => 131741-37-2
    [pslug] => 131741-37-2-2-amino-n-4-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-2-oxoacetohydrazonoyl-cyanide-pa1242580
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PA 12 42580

2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl Cyanide


  • Catalogue No.:PA 12 42580

  • CAS :

    131741-37-2

  • Molecular Formula : C14H14N6O2

  • Molecular Weight : 298.31

stdClass Object
(
    [pname] => Dextrosimendan
    [catalogue_number] => PA 12 42590
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 280.29
    [form] => C14H12N6O
    [cas] => 144238-75-5
    [pslug] => 144238-75-5-dextrosimendan-pa1242590
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PA 12 42590

Dextrosimendan


  • Catalogue No.:PA 12 42590

  • CAS :

    144238-75-5

  • Molecular Formula : C14H12N6O

  • Molecular Weight : 280.29

stdClass Object
(
    [pname] => (S)-5-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one
    [catalogue_number] => PA 12 0421001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 188.23
    [form] => C11H12N2O
    [cas] => 2290570-69-1
    [pslug] => 2290570-69-1-s-5-methyl-6-phenyl-4-5-dihydropyridazin-3-2h-one-pa120421001
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PA 12 0421001

(S)-5-Methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one


  • Catalogue No.:PA 12 0421001

  • CAS :

    2290570-69-1

  • Molecular Formula : C11H12N2O

  • Molecular Weight : 188.23

stdClass Object
(
    [pname] => (E)-2-(4-((E)-Isocyano(2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)methyl)-2H-1,3-oxazet-2-ylidene)-2-((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)acetonitrile
    [catalogue_number] => PA 12 0421002
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 561.57
    [form] => C28H23N11O3
    [cas] => NA
    [pslug] => e-2-4-e-isocyano-2-4-r-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-hydrazono-methyl-2h-1-3-oxazet-2-ylidene-2-e-4-r-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-diazenyl-acetonitrile-pa120421002
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PA 12 0421002

(E)-2-(4-((E)-Isocyano(2-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)methyl)-2H-1,3-oxazet-2-ylidene)-2-((E)-(4-((R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)diazenyl)acetonitrile


  • Catalogue No.:PA 12 0421002

  • CAS :

    NA

  • Molecular Formula : C28H23N11O3

  • Molecular Weight : 561.57

stdClass Object
(
    [pname] => (R,Z)-2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide
    [catalogue_number] => PA 12 0421003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 298.31
    [form] => C14H14N6O2
    [cas] => NA
    [pslug] => r-z-2-amino-n-4-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-2-oxoacetohydrazonoyl-cyanide-pa120421003
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PA 12 0421003

(R,Z)-2-Amino-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)-2-oxoacetohydrazonoyl cyanide


  • Catalogue No.:PA 12 0421003

  • CAS :

    NA

  • Molecular Formula : C14H14N6O2

  • Molecular Weight : 298.31

stdClass Object
(
    [pname] => 4-(4-(2-(Dicyanomethylene)hydrazinyl)phenyl)-3-methyl-4-oxobutanoic Acid
    [catalogue_number] => PA 12 0421004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 284.28
    [form] => C14H12N4O3
    [cas] => NA
    [pslug] => 4-4-2-dicyanomethylene-hydrazinyl-phenyl-3-methyl-4-oxobutanoic-acid-pa120421004
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PA 12 0421004

4-(4-(2-(Dicyanomethylene)hydrazinyl)phenyl)-3-methyl-4-oxobutanoic Acid


  • Catalogue No.:PA 12 0421004

  • CAS :

    NA

  • Molecular Formula : C14H12N4O3

  • Molecular Weight : 284.28

stdClass Object
(
    [pname] => (R)-N-Acetyl-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
    [catalogue_number] => PA 12 0421005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 245.28
    [form] => C13H15N3O2
    [cas] => 220246-81-1
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PA 12 0421005

(R)-N-Acetyl-6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone


  • Catalogue No.:PA 12 0421005

  • CAS :

    220246-81-1

  • Molecular Formula : C13H15N3O2

  • Molecular Weight : 245.28

stdClass Object
(
    [pname] => Methyl (R,E)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate
    [catalogue_number] => PA 12 0421006
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 313.32
    [form] => C15H15N5O3
    [cas] => NA
    [pslug] => methyl-r-e-2-cyano-2-2-4-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-hydrazono-acetate-pa120421006
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PA 12 0421006

Methyl (R,E)-2-cyano-2-(2-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)hydrazono)acetate


  • Catalogue No.:PA 12 0421006

  • CAS :

    NA

  • Molecular Formula : C15H15N5O3

  • Molecular Weight : 313.32

stdClass Object
(
    [pname] => (R)-N'-(Dicyanomethylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous Hydrazide
    [catalogue_number] => PA 12 0421007
    [category_ids] => ,78,70,82,162,
    [chemical_name] => 
    [weight] => 309.29
    [form] => C14H11N7O2
    [cas] => NA
    [pslug] => r-n-dicyanomethylene-n-4-4-methyl-6-oxo-1-4-5-6-tetrahydropyridazin-3-yl-phenyl-nitrous-hydrazide-pa120421007
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PA 12 0421007

(R)-N'-(Dicyanomethylene)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)nitrous Hydrazide


  • Catalogue No.:PA 12 0421007

  • CAS :

    NA

  • Molecular Formula : C14H11N7O2

  • Molecular Weight : 309.29