Leflunomide-impurities | Pharmaffiliates

leflunomide

An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Leflunomide - Impurity B
    [catalogue_number] => PA 12 08020
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    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
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PA 12 08020

Leflunomide - Impurity B


  • Catalogue No.:PA 12 08020

  • CAS :

    163451-81-8

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

20% OFF
stdClass Object
(
    [pname] => Leflunomide - Impurity A (Hydrochloride)
    [catalogue_number] => PA 12 0080011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 197.59
    [form] => C7H7ClF3N
    [cas] => 90774-69-9
    [pslug] => 90774-69-9-leflunomide-impurity-a-hydrochloride-pa120080011
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PA 12 0080011

Leflunomide - Impurity A (Hydrochloride)


  • Catalogue No.:PA 12 0080011

  • CAS :

    90774-69-9

  • Molecular Formula : C7H7ClF3N

  • Molecular Weight : 197.59

stdClass Object
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    [pname] => A77 1726-d4
    [catalogue_number] => PA STI 008740
    [category_ids] => ,76,75,117,98,
    [chemical_name] => 
    [weight] => 274.23
    [form] => C12H5D4F3N2O2
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PA STI 008740

A77 1726-d4


  • Catalogue No.:PA STI 008740

  • CAS :

    1185240-22-5

  • Molecular Formula : C12H5D4F3N2O2

  • Molecular Weight : 274.23

stdClass Object
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    [pname] => 5-Hydroxy Leflunomide-d4 (Metabolite M2)
    [catalogue_number] => PA STI 049540
    [category_ids] => ,80,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 290.23
    [form] => C12H5D4F3N2O3
    [cas] => 1794789-76-6
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PA STI 049540

5-Hydroxy Leflunomide-d4 (Metabolite M2)


  • Catalogue No.:PA STI 049540

  • CAS :

    1794789-76-6

  • Molecular Formula : C12H5D4F3N2O3

  • Molecular Weight : 290.23

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    [catalogue_number] => PA 12 08530
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    [chemical_name] => 
    [weight] => 270.21
    [form] => C12H9F3N2O2
    [cas] => 108605-62-5
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PA 12 08530

2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide


  • Catalogue No.:PA 12 08530

  • CAS :

    108605-62-5

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

stdClass Object
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    [pname] => 5-Hydroxy leflunomide
    [catalogue_number] => PA 12 0081000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 286.21
    [form] => C12H9F3N2O3
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PA 12 0081000

5-Hydroxy leflunomide


  • Catalogue No.:PA 12 0081000

  • CAS :

    1058722-46-5

  • Molecular Formula : C12H9F3N2O3

  • Molecular Weight : 286.21

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    [pname] =>  2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide
    [catalogue_number] => PA 12 0081001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 228.17
    [form] => C10H7F3N2O
    [cas] => 419534-37-5
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PA 12 0081001

 2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide


  • Catalogue No.:PA 12 0081001

  • CAS :

    419534-37-5

  • Molecular Formula : C10H7F3N2O

  • Molecular Weight : 228.17