methotrexate
An antimetabolite of the antifolate type, Methotrexate is an chemotherapy drug and used for treating autoimmune diseases like psoriasis, rheumatoid arthritis. It causes life threatening side effects. Reference standards of Methotrexate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Methotrexate - Impurity A (Hydrochloride Salt)
Catalogue No.:PA 13 0280011
Molecular Formula : C7H9ClN6O
Molecular Weight : 228.64
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7-Methylpteridine-2,4-diamine
Catalogue No.:PA 13 0281010
Molecular Formula : C7H8N6
Molecular Weight : 176.18
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Methotrexate - Impurity B (Hydrate Salt)
Catalogue No.:PA 13 0280021
Molecular Formula : C19H22N8O6
Molecular Weight : 458.44
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7-Hydroxy Methotrexate-d3
Catalogue No.:PA STI 049680
Molecular Formula : C20H19D3N8O6
Molecular Weight : 473.46
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[catalogue_number] => PA 13 28110
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Methotrexate - Impurity K
Catalogue No.:PA 13 28110
Molecular Formula : C12H14N2O5
Molecular Weight : 266.25
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Catalogue No.:PA 13 0281000
Molecular Formula : C20H21N7O5
Molecular Weight : 439.43
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7-Cyanomethotrexate Dimethyl Ester
Catalogue No.:PA 13 0281001
Molecular Formula : C23H25N9O5
Molecular Weight : 507.51
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Methotrexate-d3 Dimethyl Ester
Catalogue No.:PA 13 0281002
Molecular Formula : C22H23D3N8O5
Molecular Weight : 485.52
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Catalogue No.:PA 13 0281003
Molecular Formula : C20H22N8O6
Molecular Weight : 470.45
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(2,4-Diaminopteridin-7-yl)methanol
Catalogue No.:PA 13 0281004
Molecular Formula : C7H8N6O
Molecular Weight : 192.18
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Catalogue No.:PA 13 0281005
Molecular Formula : C6H6N6
Molecular Weight : 162.16
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6-Methylpteridine-2,4-diamine
Catalogue No.:PA 13 0281006
Molecular Formula : C7H8N6
Molecular Weight : 176.18
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[catalogue_number] => PA 13 0281007
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(4-Chlorobenzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281007
Molecular Formula : C12H12ClNO5
Molecular Weight : 285.68
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[pname] => Methotrexate System Suitability Mixture
[catalogue_number] => PA 13 0281008
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Methotrexate System Suitability Mixture
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[weight] => 454.45
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Catalogue No.:PA 13 0281009
Molecular Formula : C19H22N10O4
Molecular Weight : 454.45
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[pname] => Methotrexate - Impurity E (Freebase)
[catalogue_number] => PA 13 0280051
[category_ids] => 82,78,76,75,70
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[weight] => 325.33
[form] => C15H15N7O2
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Methotrexate - Impurity E (Freebase)
Catalogue No.:PA 13 0280051
Molecular Formula : C15H15N7O2
Molecular Weight : 325.33
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[catalogue_number] => PA 13 0281011
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Diethyl (4-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281011
Molecular Formula : C17H24N2O5
Molecular Weight : 336.39
stdClass Object
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Sodium (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)-N-nitrosobenzamido)-2-methylpentanedioate
Catalogue No.:PA 13 0281012
Molecular Formula : C21H21N9Na2O6
Molecular Weight : 541.44
stdClass Object
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(4-(((2,4-Diaminopteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281013
Molecular Formula : C19H19N9O6
Molecular Weight : 469.42
stdClass Object
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N-(4-(Methylamino)benzoyl)-N-nitroso-L-glutamic Acid
Catalogue No.:PA 13 0281014
Molecular Formula : C13H15N3O6
Molecular Weight : 309.28
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(4-(Methyl(nitroso)amino)benzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281015
Molecular Formula : C13H15N3O6
Molecular Weight : 309.28
stdClass Object
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[weight] => 338.28
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N-(4-(Methyl(nitroso)amino)benzoyl)-N-nitroso-L-glutamic Acid
Catalogue No.:PA 13 0281016
Molecular Formula : C13H14N4O7
Molecular Weight : 338.28
stdClass Object
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Diethyl (3-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281030
Molecular Formula : C17H24N2O5
Molecular Weight : 336.39
stdClass Object
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[catalogue_number] => PA 13 0281031
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Diethyl (2-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281031
Molecular Formula : C17H24N2O5
Molecular Weight : 336.39