Rapamycin-impurities | Pharmaffiliates

rapamycin

Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2.Reference standards of Rapamycin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => 27-O-Desmethyl Rapamycin
    [catalogue_number] => PA 18 26530
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 900.17
    [form] => C50H77NO13
    [cas] => NA
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PA 18 26530

27-O-Desmethyl Rapamycin


  • Catalogue No.:PA 18 26530

  • CAS :

    NA

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.17

stdClass Object
(
    [pname] => Prolyl-rapamycin
    [catalogue_number] => PA 18 26560
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 900.15
    [form] => C50H77NO13
    [cas] => NA
    [pslug] => prolyl-rapamycin-pa1826560
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PA 18 26560

Prolyl-rapamycin


  • Catalogue No.:PA 18 26560

  • CAS :

    NA

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.15

stdClass Object
(
    [pname] => 12-Desmethyl Rapamycin
    [catalogue_number] => PA 18 26570
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 900.15
    [form] => C50H77NO13
    [cas] => NA
    [pslug] => 12-desmethyl-rapamycin-pa1826570
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PA 18 26570

12-Desmethyl Rapamycin


  • Catalogue No.:PA 18 26570

  • CAS :

    NA

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.15

stdClass Object
(
    [pname] => 29-Desmethyl-rapamycin
    [catalogue_number] => PA 18 26580
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 900.15
    [form] => C50H77NO13
    [cas] => NA
    [pslug] => 29-desmethyl-rapamycin-pa1826580
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PA 18 26580

29-Desmethyl-rapamycin


  • Catalogue No.:PA 18 26580

  • CAS :

    NA

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.15

stdClass Object
(
    [pname] => 44-Ene-rapamycin
    [catalogue_number] => PA 18 26590
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 912.16
    [form] => C51H77NO13
    [cas] => NA
    [pslug] => 44-ene-rapamycin-pa1826590
    [latest_product] => 0
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PA 18 26590

44-Ene-rapamycin


  • Catalogue No.:PA 18 26590

  • CAS :

    NA

  • Molecular Formula : C51H77NO13

  • Molecular Weight : 912.16

stdClass Object
(
    [pname] => (19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt
    [catalogue_number] => PA STI 047640
    [category_ids] => ,92,69,74,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 984.23
    [form] => C53H78D4NNaO14
    [cas] => NA
    [pslug] => 19e-z-seco-4-o-2-hydroxy-ethyl-d4-rapamycin-sodium-salt-pasti047640
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PA STI 047640

(19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt


  • Catalogue No.:PA STI 047640

  • CAS :

    NA

  • Molecular Formula : C53H78D4NNaO14

  • Molecular Weight : 984.23

stdClass Object
(
    [pname] => 7-O-Demethyl Rapamycin
    [catalogue_number] => PA 18 26650
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 900.16
    [form] => C50H77NO13
    [cas] => 151519-50-5
    [pslug] => 151519-50-5-7-o-demethyl-rapamycin-pa1826650
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PA 18 26650

7-O-Demethyl Rapamycin


  • Catalogue No.:PA 18 26650

  • CAS :

    151519-50-5

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.16

stdClass Object
(
    [pname] => Secorapamycin
    [catalogue_number] => PA 18 0261000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 936.17
    [form] =>  C51H78NNaO13
    [cas] => 148554-65-8
    [pslug] => 148554-65-8-secorapamycin-pa180261000
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PA 18 0261000

Secorapamycin


  • Catalogue No.:PA 18 0261000

  • CAS :

    148554-65-8

  • Molecular Formula : C51H78NNaO13

  • Molecular Weight : 936.17

stdClass Object
(
    [pname] => 7-​O-​Demethyl-​7-​O-​ethyl-Rapamycin
    [catalogue_number] => PA 18 0261001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 928.21
    [form] => C52H81NO13
    [cas] => 157054-84-7
    [pslug] => 157054-84-7-7-​o-​demethyl-​7-​o-​ethyl-rapamycin-pa180261001
    [latest_product] => 0
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PA 18 0261001

7-​O-​Demethyl-​7-​O-​ethyl-Rapamycin


  • Catalogue No.:PA 18 0261001

  • CAS :

    157054-84-7

  • Molecular Formula : C52H81NO13

  • Molecular Weight : 928.21

stdClass Object
(
    [pname] => 42-O-[2-[[Hydroxy[2-(trimethylammonio)ethoxy]phosphinyl]oxy]ethyl] Rapamycin Inner Salt
    [catalogue_number] => PA 18 0261002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 1123.37
    [form] => C58H95N2O17P
    [cas] => 1062645-51-5
    [pslug] => 1062645-51-5-42-o-2-hydroxy-2-trimethylammonio-ethoxy-phosphinyl-oxy-ethyl-rapamycin-inner-salt-pa180261002
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PA 18 0261002

42-O-[2-[[Hydroxy[2-(trimethylammonio)ethoxy]phosphinyl]oxy]ethyl] Rapamycin Inner Salt


  • Catalogue No.:PA 18 0261002

  • CAS :

    1062645-51-5

  • Molecular Formula : C58H95N2O17P

  • Molecular Weight : 1123.37

stdClass Object
(
    [pname] => 32-O-Demethyl-rapamycin
    [catalogue_number] => PA 18 0261004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 900.15
    [form] => C50H77NO13
    [cas] => 141392-23-6
    [pslug] => 141392-23-6-32-o-demethyl-rapamycin-pa180261004
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PA 18 0261004

32-O-Demethyl-rapamycin


  • Catalogue No.:PA 18 0261004

  • CAS :

    141392-23-6

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.15

stdClass Object
(
    [pname] => Omipalisib
    [catalogue_number] => PA 18 0261005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 505.5
    [form] => C25H17F2N5O3S
    [cas] => 1086062-66-9
    [pslug] => 1086062-66-9-omipalisib-pa180261005
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PA 18 0261005

Omipalisib


  • Catalogue No.:PA 18 0261005

  • CAS :

    1086062-66-9

  • Molecular Formula : C25H17F2N5O3S

  • Molecular Weight : 505.5

stdClass Object
(
    [pname] => Torin 2
    [catalogue_number] => PA 18 0261006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 432.41
    [form] => C24H15F3N4O
    [cas] => 1223001-51-1
    [pslug] => 1223001-51-1-torin-2-pa180261006
    [latest_product] => 0
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PA 18 0261006

Torin 2


  • Catalogue No.:PA 18 0261006

  • CAS :

    1223001-51-1

  • Molecular Formula : C24H15F3N4O

  • Molecular Weight : 432.41

stdClass Object
(
    [pname] => 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    [catalogue_number] => PA 18 0261007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 309.33
    [form] => C15H15N7O
    [cas] => 1224844-38-5
    [pslug] => 1224844-38-5-3-2-amino-5-benzoxazolyl-1-1-methylethyl-1h-pyrazolo-3-4-d-pyrimidin-4-amine-pa180261007
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PA 18 0261007

3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine


  • Catalogue No.:PA 18 0261007

  • CAS :

    1224844-38-5

  • Molecular Formula : C15H15N7O

  • Molecular Weight : 309.33

stdClass Object
(
    [pname] => 21-Norrapamycin
    [catalogue_number] => PA 18 0261008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 900.16
    [form] => C50H77NO13
    [cas] => 156223-31-3
    [pslug] => 156223-31-3-21-norrapamycin-pa180261008
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PA 18 0261008

21-Norrapamycin


  • Catalogue No.:PA 18 0261008

  • CAS :

    156223-31-3

  • Molecular Formula : C50H77NO13

  • Molecular Weight : 900.16

stdClass Object
(
    [pname] => Sirolimus 13C D3
    [catalogue_number] => PA STI 089156
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 918.2
    [form] => C5013CH76D3NO13
    [cas] => NA
    [pslug] => sirolimus-13c-d3-pasti089156
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PA STI 089156

Sirolimus 13C D3


  • Catalogue No.:PA STI 089156

  • CAS :

    NA

  • Molecular Formula : C5013CH76D3NO13

  • Molecular Weight : 918.2

stdClass Object
(
    [pname] => Rapamycin, 36-demethyl-36-ethyl
    [catalogue_number] => PA 18 0261010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 928.21
    [form] => C52H81NO13
    [cas] => 1290606-21-1
    [pslug] => 1290606-21-1-rapamycin-36-demethyl-36-ethyl-pa180261010
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PA 18 0261010

Rapamycin, 36-demethyl-36-ethyl


  • Catalogue No.:PA 18 0261010

  • CAS :

    1290606-21-1

  • Molecular Formula : C52H81NO13

  • Molecular Weight : 928.21

stdClass Object
(
    [pname] => 42-Oxorapamycin
    [catalogue_number] => PA 18 0261009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 912.17
    [form] => C51H77NO13
    [cas] => 136293-03-3
    [pslug] => 136293-03-3-42-oxorapamycin-pa180261009
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PA 18 0261009

42-Oxorapamycin


  • Catalogue No.:PA 18 0261009

  • CAS :

    136293-03-3

  • Molecular Formula : C51H77NO13

  • Molecular Weight : 912.17

stdClass Object
(
    [pname] => Secorapamycin B
    [catalogue_number] => PA 18 0261011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 932.2
    [form] => C51H81NO14
    [cas] => 185107-79-3
    [pslug] => 185107-79-3-secorapamycin-b-pa180261011
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PA 18 0261011

Secorapamycin B


  • Catalogue No.:PA 18 0261011

  • CAS :

    185107-79-3

  • Molecular Formula : C51H81NO14

  • Molecular Weight : 932.2