Afatinib-Impurities | Pharmaffiliates

afatinib

afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif. Reference standards of Afatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 02680
    [category_ids] => ,79,80,71,84,
    [chemical_name] => 
    [weight] => 502.39
    [form] => C24H25Cl2N5O3
    [cas] => 2223677-63-0
    [pslug] => 2223677-63-0-s-e-n-4-3-4-dichlorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802680
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PA 28 02680

(S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 02680

  • CAS :

    2223677-63-0

  • Molecular Formula : C24H25Cl2N5O3

  • Molecular Weight : 502.39

stdClass Object
(
    [pname] => (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
    [catalogue_number] => PA 28 02700
    [category_ids] => ,79,80,71,84,
    [chemical_name] => 
    [weight] => 358.39
    [form] => C18H22N4O4
    [cas] => NA
    [pslug] => s-e-4-dimethylamino-n-4-hydroxy-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-but-2-enamide-pa2802700
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PA 28 02700

(S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide


  • Catalogue No.:PA 28 02700

  • CAS :

    NA

  • Molecular Formula : C18H22N4O4

  • Molecular Weight : 358.39