Crizotinib-impurities | Pharmaffiliates

crizotinib

Crizotinib is used to treat certain types of lung cancer. It works by slowing or stopping the growth of lung cancer cells. It belongs to a class of drugs known as kinase inhibitors. Reference standards of Crizotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Crizotinib - API Standards 
    [catalogue_number] => PA 03 3850000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 450.34
    [form] => C21H22Cl2FN5O
    [cas] => 877399-52-5
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PA 03 3850000

Crizotinib - API Standards


  • Catalogue No.:PA 03 3850000

  • CAS :

    877399-52-5

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

20% OFF
stdClass Object
(
    [pname] => (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
    [catalogue_number] => PA 03 3851003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 380.04
    [form] => C13H10BrCl2FN2O
    [cas] => 877399-00-3
    [pslug] => 877399-00-3-r-5-bromo-3-1-2-6-dichloro-3-fluorophenyl-ethoxy-pyridin-2-amine-pa033851003
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    [offers_product_code] => PA 03 3851003
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PA 03 3851003

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine


  • Catalogue No.:PA 03 3851003

  • CAS :

    877399-00-3

  • Molecular Formula : C13H10BrCl2FN2O

  • Molecular Weight : 380.04

20% OFF
stdClass Object
(
    [pname] => Crizotinib-d5
    [catalogue_number] => PA STI 022770
    [category_ids] => ,80,69,71,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 455.37
    [form] => C21H17D5Cl2FN5O
    [cas] => 1395950-48-7
    [pslug] => 1395950-48-7-crizotinib-d5-pasti022770
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PA STI 022770

Crizotinib-d5


  • Catalogue No.:PA STI 022770

  • CAS :

    1395950-48-7

  • Molecular Formula : C21H17D5Cl2FN5O

  • Molecular Weight : 455.37

stdClass Object
(
    [pname] => (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
    [catalogue_number] => PA STI 088317
    [category_ids] => ,98,78,70,82,
    [chemical_name] => 
    [weight] => 455.37
    [form] => C21H17D5Cl2FN5O
    [cas] => 1395950-84-1
    [pslug] => 1395950-84-1-r-crizotinib-d5-piperidine-3-3-4-5-5-d5-pasti088317
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PA STI 088317

(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)


  • Catalogue No.:PA STI 088317

  • CAS :

    1395950-84-1

  • Molecular Formula : C21H17D5Cl2FN5O

  • Molecular Weight : 455.37

stdClass Object
(
    [pname] => 2-Keto Crizotinib
    [catalogue_number] => PA 03 3851000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 464.32
    [form] => C21H20Cl2FN5O2
    [cas] => 1415558-82-5
    [pslug] => 1415558-82-5-2-keto-crizotinib-pa033851000
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PA 03 3851000

2-Keto Crizotinib


  • Catalogue No.:PA 03 3851000

  • CAS :

    1415558-82-5

  • Molecular Formula : C21H20Cl2FN5O2

  • Molecular Weight : 464.32

stdClass Object
(
    [pname] => (S)-Crizotinib
    [catalogue_number] => PA 03 3851001
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 450.34
    [form] => C21H22Cl2FN5O
    [cas] => 1374356-45-2
    [pslug] => 1374356-45-2-s-crizotinib-pa033851001
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PA 03 3851001

(S)-Crizotinib


  • Catalogue No.:PA 03 3851001

  • CAS :

    1374356-45-2

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

stdClass Object
(
    [pname] => (R,S)-Crizotinib
    [catalogue_number] => PA 03 3851002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 450.34
    [form] => C21H22Cl2FN5O
    [cas] => 877400-66-3
    [pslug] => 877400-66-3-r-s-crizotinib-pa033851002
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PA 03 3851002

(R,S)-Crizotinib


  • Catalogue No.:PA 03 3851002

  • CAS :

    877400-66-3

  • Molecular Formula : C21H22Cl2FN5O

  • Molecular Weight : 450.34

stdClass Object
(
    [pname] => (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
    [catalogue_number] => PA 03 3851004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 492.42
    [form] => C24H28Cl2FN5O
    [cas] => NA
    [pslug] => r-3-1-2-6-dichloro-3-fluorophenyl-ethoxy-5-1-1-isopropylpiperidin-4-yl-1h-pyrazol-4-yl-pyridin-2-amine-pa033851004
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PA 03 3851004

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine


  • Catalogue No.:PA 03 3851004

  • CAS :

    NA

  • Molecular Formula : C24H28Cl2FN5O

  • Molecular Weight : 492.42

stdClass Object
(
    [pname] => (R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
    [catalogue_number] => PA 03 3851005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 522.45
    [form] => C25H30Cl2FN5O2
    [cas] => NA
    [pslug] => r-4-4-4-6-amino-5-1-2-6-dichloro-3-fluorophenyl-ethoxy-pyridin-3-yl-1h-pyrazol-1-yl-piperidin-1-yl-butan-1-ol-pa033851005
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PA 03 3851005

(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol


  • Catalogue No.:PA 03 3851005

  • CAS :

    NA

  • Molecular Formula : C25H30Cl2FN5O2

  • Molecular Weight : 522.45

stdClass Object
(
    [pname] => tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
    [catalogue_number] => PA 03 3851006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 550.46
    [form] => C26H30Cl2FN5O3
    [cas] => 877399-51-4
    [pslug] => 877399-51-4-tert-butyl-r-4-4-6-amino-5-1-2-6-dichloro-3-fluorophenyl-ethoxy-pyridin-3-yl-1h-pyrazol-1-yl-piperidine-1-carboxylate-pa033851006
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PA 03 3851006

tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate


  • Catalogue No.:PA 03 3851006

  • CAS :

    877399-51-4

  • Molecular Formula : C26H30Cl2FN5O3

  • Molecular Weight : 550.46

stdClass Object
(
    [pname] => Crizotinib Amine Impurity
    [catalogue_number] => PA 03 3851007
    [category_ids] => ,75,76,71,78,70,82,
    [chemical_name] => 
    [weight] => 301.14
    [form] => C13H11Cl2FN2O
    [cas] => 877397-71-2
    [pslug] => 877397-71-2-crizotinib-amine-impurity-pa033851007
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PA 03 3851007

Crizotinib Amine Impurity


  • Catalogue No.:PA 03 3851007

  • CAS :

    877397-71-2

  • Molecular Formula : C13H11Cl2FN2O

  • Molecular Weight : 301.14

stdClass Object
(
    [pname] => (R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol
    [catalogue_number] => PA 03 3851008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 466.34
    [form] => C21H22Cl2FN5O2
    [cas] => NA
    [pslug] => r-4-4-6-amino-5-1-2-6-dichloro-3-fluorophenyl-ethoxy-pyridin-3-yl-1h-pyrazol-1-yl-piperidin-1-ol-pa033851008
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PA 03 3851008

(R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol


  • Catalogue No.:PA 03 3851008

  • CAS :

    NA

  • Molecular Formula : C21H22Cl2FN5O2

  • Molecular Weight : 466.34

stdClass Object
(
    [pname] => (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine
    [catalogue_number] => PA 03 3851009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 367.21
    [form] => C16H13Cl2FN4O
    [cas] => 3026867-46-6
    [pslug] => 3026867-46-6-r-3-1-2-6-dichloro-3-fluorophenyl-ethoxy-5-1h-pyrazol-4-yl-pyridin-2-amine-pa033851009
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PA 03 3851009

(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine


  • Catalogue No.:PA 03 3851009

  • CAS :

    3026867-46-6

  • Molecular Formula : C16H13Cl2FN4O

  • Molecular Weight : 367.21

stdClass Object
(
    [pname] => tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
    [catalogue_number] => PA 03 3851010
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 377.29
    [form] => C19H32BN3O4
    [cas] => 877399-74-1
    [pslug] => 877399-74-1-tert-butyl-4-4-4-4-5-5-tetramethyl-1-3-2-dioxaborolan-2-yl-1h-pyrazol-1-yl-piperidine-1-carboxylate-pa033851010
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PA 03 3851010

tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate


  • Catalogue No.:PA 03 3851010

  • CAS :

    877399-74-1

  • Molecular Formula : C19H32BN3O4

  • Molecular Weight : 377.29