crizotinib
Crizotinib is used to treat certain types of lung cancer. It works by slowing or stopping the growth of lung cancer cells. It belongs to a class of drugs known as kinase inhibitors. Reference standards of Crizotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Crizotinib - API Standards
[catalogue_number] => PA 03 3850000
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[weight] => 450.34
[form] => C21H22Cl2FN5O
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Crizotinib - API Standards
Catalogue No.:PA 03 3850000
Molecular Formula : C21H22Cl2FN5O
Molecular Weight : 450.34
stdClass Object
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[pname] => (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
[catalogue_number] => PA 03 3851003
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[chemical_name] =>
[weight] => 380.04
[form] => C13H10BrCl2FN2O
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(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Catalogue No.:PA 03 3851003
Molecular Formula : C13H10BrCl2FN2O
Molecular Weight : 380.04
stdClass Object
(
[pname] => Crizotinib-d5
[catalogue_number] => PA STI 022770
[category_ids] => ,80,69,71,81,78,70,82,98,
[chemical_name] =>
[weight] => 455.37
[form] => C21H17D5Cl2FN5O
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Catalogue No.:PA STI 022770
Molecular Formula : C21H17D5Cl2FN5O
Molecular Weight : 455.37
stdClass Object
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[pname] => (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
[catalogue_number] => PA STI 088317
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[weight] => 455.37
[form] => C21H17D5Cl2FN5O
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(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
Catalogue No.:PA STI 088317
Molecular Formula : C21H17D5Cl2FN5O
Molecular Weight : 455.37
stdClass Object
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[pname] => 2-Keto Crizotinib
[catalogue_number] => PA 03 3851000
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[weight] => 464.32
[form] => C21H20Cl2FN5O2
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Catalogue No.:PA 03 3851000
Molecular Formula : C21H20Cl2FN5O2
Molecular Weight : 464.32
stdClass Object
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[pname] => (S)-Crizotinib
[catalogue_number] => PA 03 3851001
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[weight] => 450.34
[form] => C21H22Cl2FN5O
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Catalogue No.:PA 03 3851001
Molecular Formula : C21H22Cl2FN5O
Molecular Weight : 450.34
stdClass Object
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Catalogue No.:PA 03 3851002
Molecular Formula : C21H22Cl2FN5O
Molecular Weight : 450.34
stdClass Object
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[pname] => (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
[catalogue_number] => PA 03 3851004
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[chemical_name] =>
[weight] => 492.42
[form] => C24H28Cl2FN5O
[cas] => NA
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(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851004
Molecular Formula : C24H28Cl2FN5O
Molecular Weight : 492.42
stdClass Object
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[pname] => (R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
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[weight] => 522.45
[form] => C25H30Cl2FN5O2
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(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
Catalogue No.:PA 03 3851005
Molecular Formula : C25H30Cl2FN5O2
Molecular Weight : 522.45
stdClass Object
(
[pname] => tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
[catalogue_number] => PA 03 3851006
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[weight] => 550.46
[form] => C26H30Cl2FN5O3
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tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851006
Molecular Formula : C26H30Cl2FN5O3
Molecular Weight : 550.46
stdClass Object
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[pname] => Crizotinib Amine Impurity
[catalogue_number] => PA 03 3851007
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[weight] => 301.14
[form] => C13H11Cl2FN2O
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Crizotinib Amine Impurity
Catalogue No.:PA 03 3851007
Molecular Formula : C13H11Cl2FN2O
Molecular Weight : 301.14
stdClass Object
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[pname] => (R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol
[catalogue_number] => PA 03 3851008
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[chemical_name] =>
[weight] => 466.34
[form] => C21H22Cl2FN5O2
[cas] => NA
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(R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol
Catalogue No.:PA 03 3851008
Molecular Formula : C21H22Cl2FN5O2
Molecular Weight : 466.34
stdClass Object
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[catalogue_number] => PA 03 3851009
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[chemical_name] =>
[weight] => 367.21
[form] => C16H13Cl2FN4O
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(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851009
Molecular Formula : C16H13Cl2FN4O
Molecular Weight : 367.21
stdClass Object
(
[pname] => tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
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[weight] => 377.29
[form] => C19H32BN3O4
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tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851010
Molecular Formula : C19H32BN3O4
Molecular Weight : 377.29