famotidine
Famotidine is a medicine used for the treatment of gastric ulcers, stomach acid production, heartburn and gastroesophageal reflux . It is a histamine H2 receptor antagonist and it is an over-the-counter drug. Reference standards of Famotidine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Famotidine - API Standards
Catalogue No.:PA 06 01000
Molecular Formula : C8H15N7O2S3
Molecular Weight : 337.45
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Famotidine - Impurity A (Hydrochloride Salt)
Catalogue No.:PA 06 01010
Molecular Formula : C8H15ClN6S2
Molecular Weight : 294.83
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[catalogue_number] => PA 06 01020
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[weight] => 561.76
[form] => C16H23N11O2S5
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Catalogue No.:PA 06 01020
Molecular Formula : C16H23N11O2S5
Molecular Weight : 561.76
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[weight] => 259.35
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Catalogue No.:PA 06 01040
Molecular Formula : C8H13N5OS2
Molecular Weight : 259.35
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Catalogue No.:PA 06 01050
Molecular Formula : C10H14N8S4
Molecular Weight : 374.53
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Catalogue No.:PA 06 01060
Molecular Formula : C8H12N4O2S2
Molecular Weight : 260.34
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Catalogue No.:PA 06 01070
Molecular Formula : C9H13N7S2
Molecular Weight : 283.38
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Catalogue No.:PA 06 01090
Molecular Formula : C8H14N6O4S3
Molecular Weight : 354.43
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Famotidine - Impurity G (Maleate Salt)
Catalogue No.:PA 06 01071
Molecular Formula : C13H17N7O4S2
Molecular Weight : 399.44
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Catalogue No.:PA 06 01080
Molecular Formula : C6H10N6S2
Molecular Weight : 230.31
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Famotidine - Impurity A (Freebase)
Catalogue No.:PA 06 01011
Molecular Formula : C8H14N6S2
Molecular Weight : 258.36
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Famotidine - Impurity A (Dihydrochloride Salt)
Catalogue No.:PA 06 0011000
Molecular Formula : C8H16Cl2N6S2
Molecular Weight : 331.28
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Famotidine - Impurity G (Hydrochloride Salt)
Catalogue No.:PA 06 01072
Molecular Formula : C9H14ClN7S2
Molecular Weight : 319.83
stdClass Object
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2-(4-(((2-Cyanoethyl)thio)methyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 01520
Molecular Formula : C8H11N5S2
Molecular Weight : 241.34
stdClass Object
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Famotidine - Impurity D (Hydrochloride Salt)
Catalogue No.:PA 06 01530
Molecular Formula : C8H14ClN5OS2
Molecular Weight : 295.81
stdClass Object
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Famotidine Acid Methyl Ester Acetic Acid Salt (Famotidine Impurity)
Catalogue No.:PA 06 01540
Molecular Formula : C11H18N4O4S2
Molecular Weight : 334.42
stdClass Object
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S-(2-Guanidino-4-thiazolyl)methylisothiourea Dihydrochloride
Catalogue No.:PA 06 01550
Molecular Formula : C6H12Cl2N6S2
Molecular Weight : 303.24
stdClass Object
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1-(4-Methylthiazol-2-yl)guanidine Hydrochloride
Catalogue No.:PA 06 01560
Molecular Formula : C5H9ClN4S
Molecular Weight : 192.67
stdClass Object
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Catalogue No.:PA STI 040560
Molecular Formula : C513C3H15N7O2S3
Molecular Weight : 340.42
stdClass Object
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Catalogue No.:PA STI 040570
Molecular Formula : C8H11D4N7O2S3
Molecular Weight : 341.47
stdClass Object
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[weight] => 265.35
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Famotidine-13C,d4 Acid Impurity
Catalogue No.:PA STI 040580
Molecular Formula : C713CH8D4N4O2S2
Molecular Weight : 265.35
stdClass Object
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[weight] => 190.65
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1-(4-(Chloromethyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 0011002
Molecular Formula : C5H7ClN4S
Molecular Weight : 190.65
stdClass Object
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[pname] => 3-(((2-((Diaminomethylene)amino)thiazol-4-yl)methyl)sulfinyl)-N-sulfamoylpropanamide hydrochloride
[catalogue_number] => PA 06 0011003
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[weight] => 390.88
[form] => C8H15ClN6O4S3
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3-(((2-((Diaminomethylene)amino)thiazol-4-yl)methyl)sulfinyl)-N-sulfamoylpropanamide hydrochloride
Catalogue No.:PA 06 0011003
Molecular Formula : C8H15ClN6O4S3
Molecular Weight : 390.88
stdClass Object
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[pname] => N-(Aminosulfonyl)-3-chloropropanamide
[catalogue_number] => PA 06 0011001
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[weight] => 186.61
[form] => C3H7ClN2O3S
[cas] => 88068-99-9
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N-(Aminosulfonyl)-3-chloropropanamide
Catalogue No.:PA 06 0011001
Molecular Formula : C3H7ClN2O3S
Molecular Weight : 186.61
stdClass Object
(
[pname] => N-Sulphamyl-3-chloropropionamidine Hydrochloride
[catalogue_number] => PA 06 0011005
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[weight] => 222.08
[form] => C3H9Cl2N3O2S
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N-Sulphamyl-3-chloropropionamidine Hydrochloride
Catalogue No.:PA 06 0011005
Molecular Formula : C3H9Cl2N3O2S
Molecular Weight : 222.08
stdClass Object
(
[pname] => N-Nitroso Famotidine - I
[catalogue_number] => PA 06 0011004
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 366.43
[form] => C8H14N8O3S3
[cas] => NA
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Catalogue No.:PA 06 0011004
Molecular Formula : C8H14N8O3S3
Molecular Weight : 366.43
stdClass Object
(
[pname] => Ethyl 3-(((2-((diaminomethylene)amino)thiazol-4-yl)methyl)thio)propanimidate
[catalogue_number] => PAI 06 005051
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[chemical_name] =>
[weight] => 287.4
[form] => C10H17N5OS2
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Ethyl 3-(((2-((diaminomethylene)amino)thiazol-4-yl)methyl)thio)propanimidate
stdClass Object
(
[pname] => 1-(4-(Chloromethyl)-4-hydroxy-4,5-dihydrothiazol-2-yl)guanidine
[catalogue_number] => PA 06 0011006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 208.66
[form] => C5H9ClN4OS
[cas] => 95907-34-9
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1-(4-(Chloromethyl)-4-hydroxy-4,5-dihydrothiazol-2-yl)guanidine
Catalogue No.:PA 06 0011006
Molecular Formula : C5H9ClN4OS
Molecular Weight : 208.66
stdClass Object
(
[pname] => 3,5-bis(2-Chloroethyl)-4H-1,2,4,6-thiatriazine 1,1-dioxide
[catalogue_number] => PA 06 0011008
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[chemical_name] =>
[weight] => 258.12
[form] => C6H9Cl2N3O2S
[cas] => NA
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3,5-bis(2-Chloroethyl)-4H-1,2,4,6-thiatriazine 1,1-dioxide
Catalogue No.:PA 06 0011008
Molecular Formula : C6H9Cl2N3O2S
Molecular Weight : 258.12
stdClass Object
(
[pname] => 1-(4-(((2-(3-(Hydroxymethyl)-1,1-dioxido-3,4-dihydro-2H-1,2,4,6-thiatriazin-5-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine maleate
[catalogue_number] => PA 06 0011007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 495.54
[form] => C14H21N7O7S3
[cas] => 2575516-75-3
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1-(4-(((2-(3-(Hydroxymethyl)-1,1-dioxido-3,4-dihydro-2H-1,2,4,6-thiatriazin-5-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine maleate
Catalogue No.:PA 06 0011007
Molecular Formula : C14H21N7O7S3
Molecular Weight : 495.54
stdClass Object
(
[pname] => Famotidine-13C-d3
[catalogue_number] => PA STI 089065
[category_ids] => 98,82,78,76,75,70
[chemical_name] =>
[weight] => 341.45
[form] => C713CH12D3N7O2S3
[cas] => 2744683-81-4
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Catalogue No.:PA STI 089065
Molecular Formula : C713CH12D3N7O2S3
Molecular Weight : 341.45
stdClass Object
(
[pname] => N-Sulfamoylacrylimidamide
[catalogue_number] => PA 06 0011009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 149.17
[form] => C3H7N3O2S
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N-Sulfamoylacrylimidamide
Catalogue No.:PA 06 0011009
Molecular Formula : C3H7N3O2S
Molecular Weight : 149.17
stdClass Object
(
[pname] => (2-Aminothiazol-4-yl)methyl Carbamimidothioate
[catalogue_number] => PA 06 0011010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 188.27
[form] => C5H8N4S2
[cas] => 20166-91-0
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(2-Aminothiazol-4-yl)methyl Carbamimidothioate
Catalogue No.:PA 06 0011010
Molecular Formula : C5H8N4S2
Molecular Weight : 188.27
stdClass Object
(
[pname] => 1-((2-Guanidinothiazol-4-yl)methyl)thiourea
[catalogue_number] => PA 06 0011011
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[chemical_name] =>
[weight] => 230.31
[form] => C6H10N6S2
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1-((2-Guanidinothiazol-4-yl)methyl)thiourea
Catalogue No.:PA 06 0011011
Molecular Formula : C6H10N6S2
Molecular Weight : 230.31
stdClass Object
(
[pname] => N-(N-Benzylidenesulfamoyl)-3-(((2-guanidinothiazol-4-yl)methyl)thio)propanimidamide
[catalogue_number] => PA 06 0011012
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[weight] => 425.54
[form] => C15H19N7O2S3
[cas] => 1994267-84-3
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N-(N-Benzylidenesulfamoyl)-3-(((2-guanidinothiazol-4-yl)methyl)thio)propanimidamide
Catalogue No.:PA 06 0011012
Molecular Formula : C15H19N7O2S3
Molecular Weight : 425.54
stdClass Object
(
[pname] => 2-(4-(((2-(1,1-Dioxido-5-phenyl-5,6-dihydro-2H-1,2,4,6-thiatriazin-3-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine
[catalogue_number] => PA 06 0011013
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[weight] => 425.54
[form] => C15H19N7O2S3
[cas] => NA
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2-(4-(((2-(1,1-Dioxido-5-phenyl-5,6-dihydro-2H-1,2,4,6-thiatriazin-3-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 0011013
Molecular Formula : C15H19N7O2S3
Molecular Weight : 425.54
stdClass Object
(
[pname] => N-Nitroso Famotidine 2
[catalogue_number] => PA 06 0011014
[category_ids] => ,70,75,76,78,82,162,
[chemical_name] =>
[weight] => 366.43
[form] => C8H14N8O3S3
[cas] => NA
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Catalogue No.:PA 06 0011014
Molecular Formula : C8H14N8O3S3
Molecular Weight : 366.43
stdClass Object
(
[pname] => 1-(4-(Chloromethyl)-4-hydroxy-4,5-dihydrothiazol-2-yl)guanidine Hydrochloride
[catalogue_number] => PA 06 0011015
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[chemical_name] =>
[weight] => 245.12
[form] => C5H10Cl2N4OS
[cas] => 95907-33-8
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1-(4-(Chloromethyl)-4-hydroxy-4,5-dihydrothiazol-2-yl)guanidine Hydrochloride
Catalogue No.:PA 06 0011015
Molecular Formula : C5H10Cl2N4OS
Molecular Weight : 245.12
stdClass Object
(
[pname] => N-Sulphamyl-3-chloropropionamidine
[catalogue_number] => PA 06 0011016
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[weight] => 185.63
[form] => C3H8ClN3O2S
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N-Sulphamyl-3-chloropropionamidine
Catalogue No.:PA 06 0011016
Molecular Formula : C3H8ClN3O2S
Molecular Weight : 185.63
stdClass Object
(
[pname] => N-nitroso N-Propyl Sulfamide
[catalogue_number] => PA 06 0011017
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[weight] => 167.18
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N-nitroso N-Propyl Sulfamide
Catalogue No.:PA 06 0011017
Molecular Formula : C3H9N3O3S
Molecular Weight : 167.18
stdClass Object
(
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[catalogue_number] => PA 06 0011018
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[chemical_name] =>
[weight] => 349.45
[form] => C9H15N7O2S3
[cas] => 154754-59-3
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1-(4-(((2-(1,1-Dioxido-3,4-dihydro-2H-1,2,4,6-thiatriazin-5-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 0011018
Molecular Formula : C9H15N7O2S3
Molecular Weight : 349.45
stdClass Object
(
[pname] => (2-((Diaminomethylene)amino)thiazol-5-yl)methyl carbamimidothioate
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[weight] => 230.31
[form] => C6H10N6S2
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(2-((Diaminomethylene)amino)thiazol-5-yl)methyl carbamimidothioate
Catalogue No.:PA 06 0011019
Molecular Formula : C6H10N6S2
Molecular Weight : 230.31
stdClass Object
(
[pname] => (Z)-3-(((2-((Diaminomethylene)amino)thiazol-5-yl)methyl)thio)-N'-sulfamoylpropanimidamide
[catalogue_number] => PA 06 0011020
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[weight] => 337.44
[form] => C8H15N7O2S3
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(Z)-3-(((2-((Diaminomethylene)amino)thiazol-5-yl)methyl)thio)-N'-sulfamoylpropanimidamide
Catalogue No.:PA 06 0011020
Molecular Formula : C8H15N7O2S3
Molecular Weight : 337.44
stdClass Object
(
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[catalogue_number] => PA 06 0011021
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[chemical_name] =>
[weight] => 190.65
[form] => C5H7ClN4S
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1-(5-(Chloromethyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 0011021
Molecular Formula : C5H7ClN4S
Molecular Weight : 190.65
stdClass Object
(
[pname] => (Z)-3-Chloro-N'-sulfamoylpropanimidamide
[catalogue_number] => PA 06 0011022
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[weight] => 185.63
[form] => C3H8ClN3O2S
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(Z)-3-Chloro-N'-sulfamoylpropanimidamide
Catalogue No.:PA 06 0011022
Molecular Formula : C3H8ClN3O2S
Molecular Weight : 185.63
stdClass Object
(
[pname] => (2-Guanidinothiazol-5-yl)methyl carbamimidothioate Dihydrochloride
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[weight] => 303.22
[form] => C6H12Cl2N6S2
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(2-Guanidinothiazol-5-yl)methyl carbamimidothioate Dihydrochloride
Catalogue No.:PA 06 0011023
Molecular Formula : C6H12Cl2N6S2
Molecular Weight : 303.22
stdClass Object
(
[pname] => 3-[[(2-Amino-4-thiazolyl)methyl]thio]propanenitrile
[catalogue_number] => PA 06 0011024
[category_ids] => ,71,78,79,82,88,
[chemical_name] =>
[weight] => 199.29
[form] => C7H9N3S2
[cas] => 76823-89-7
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3-[[(2-Amino-4-thiazolyl)methyl]thio]propanenitrile
Catalogue No.:PA 06 0011024
Molecular Formula : C7H9N3S2
Molecular Weight : 199.29
stdClass Object
(
[pname] => 2-Chloro-N-sulfamoylpropanimidamide
[catalogue_number] => PA 06 0011025
[category_ids] => ,78,79,82,
[chemical_name] =>
[weight] => 185.63
[form] => C3H8ClN3O2S
[cas] => NA
[pslug] => 2-chloro-n-sulfamoylpropanimidamide-pa060011025
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2-Chloro-N-sulfamoylpropanimidamide
Catalogue No.:PA 06 0011025
Molecular Formula : C3H8ClN3O2S
Molecular Weight : 185.63
stdClass Object
(
[pname] => 2-(4-(((2-(1,1-Dioxido-3-((1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl)-3,4-dihydro-2H-1,2,4,6-thiatriazin-5-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine
[catalogue_number] => PA 06 0011026
[category_ids] => ,70,78,82,93,
[chemical_name] =>
[weight] => 499.58
[form] => C14H25N7O7S3
[cas] => NA
[pslug] => 2-4-2-1-1-dioxido-3-1s-2r-3r-4r-1-2-3-4-5-pentahydroxypentyl-3-4-dihydro-2h-1-2-4-6-thiatriazin-5-yl-ethyl-thio-methyl-thiazol-2-yl-guanidine-pa060011026
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2-(4-(((2-(1,1-Dioxido-3-((1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl)-3,4-dihydro-2H-1,2,4,6-thiatriazin-5-yl)ethyl)thio)methyl)thiazol-2-yl)guanidine
Catalogue No.:PA 06 0011026
Molecular Formula : C14H25N7O7S3
Molecular Weight : 499.58
stdClass Object
(
[pname] => 5-(2-Chloroethyl)-3,3-dimethyl-3,4-dihydro-2H-1,2,4,6-thiatriazine 1,1-dioxide
[catalogue_number] => PA 06 0011027
[category_ids] => ,70,71,78,79,82,
[chemical_name] =>
[weight] => 225.69
[form] => C6H12ClN3O2S
[cas] => NA
[pslug] => 5-2-chloroethyl-3-3-dimethyl-3-4-dihydro-2h-1-2-4-6-thiatriazine-1-1-dioxide-pa060011027
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5-(2-Chloroethyl)-3,3-dimethyl-3,4-dihydro-2H-1,2,4,6-thiatriazine 1,1-dioxide
Catalogue No.:PA 06 0011027
Molecular Formula : C6H12ClN3O2S
Molecular Weight : 225.69