sibutramine
An appetite suppressant used for the treatment of obesity and weight loss. Sibutramine is a monoamine reuptake inhibitor (MRI) which is now banned in many countries due to a high risk of cardiovascular diseases associated it. A phenethylamine derivative.Reference standards of Sibutramine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Sibutramine - API Standards
Catalogue No.:PA 19 76000
Molecular Formula : C17H26ClN
Molecular Weight : 279.85
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[form] => C15H19BrClMgN
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Magnesium Bromide {1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutylidene}azanide (1:1:1)
Catalogue No.:PA 19 45510
Molecular Formula : C15H19BrClMgN
Molecular Weight : 352.98
stdClass Object
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[form] => C15H19ClO
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1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutan-1-one
Catalogue No.:PA 19 45520
Molecular Formula : C15H19ClO
Molecular Weight : 250.76
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2,6-Bis(4-chlorophenyl)heptanedinitrile
Catalogue No.:PA 19 45530
Molecular Formula : C19H16Cl2N2
Molecular Weight : 343.25
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1-(4-Chlorophenyl)cyclobutane-d6 Carbonitrile
Catalogue No.:PA STI 020520
Molecular Formula : C11H4D6ClN
Molecular Weight : 197.69
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Desmethyl Sibutramine-d6, Hydrochloride
Catalogue No.:PA STI 028580
Molecular Formula : C16H19D6Cl2N
Molecular Weight : 308.32
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Desmethyl Sibutramine-d7 Hydrochloride
Catalogue No.:PA STI 028590
Molecular Formula : C16H18D7Cl2N
Molecular Weight : 309.33
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Didesmethyl Sibutramine-d6
Catalogue No.:PA STI 030990
Molecular Formula : C15H16D6ClN
Molecular Weight : 257.83
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Didesmethyl Sibutramine-d7 Hydrochloride
Catalogue No.:PA STI 031000
Molecular Formula : C15H16D7Cl2N
Molecular Weight : 295.30
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N-Formyl N,N-Didesmethyl Sibutramine-d6
Catalogue No.:PA STI 042840
Molecular Formula : C16H16D6ClNO
Molecular Weight : 285.84
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Catalogue No.:PA STI 079200
Molecular Formula : C17H20D6ClN
Molecular Weight : 285.88
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Sibutramine-d7 Hydrochloride
Catalogue No.:PA STI 079210
Molecular Formula : C17H20D7Cl2N
Molecular Weight : 323.35
stdClass Object
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[weight] => 316.31
[form] => C17H27Cl2N
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4-Deschloro-2-chloro Sibutramine Hydrochloride
Catalogue No.:PA 19 45540
Molecular Formula : C17H27Cl2N
Molecular Weight : 316.31
stdClass Object
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[weight] => 316.31
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(N-{1-[1-(3-Chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine Hydrochloride)
Catalogue No.:PA 19 45550
Molecular Formula : C17H27Cl2N
Molecular Weight : 316.31
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3-Desmethyl 4-Methyl Sibutramine Hydrochloride
Catalogue No.:PA 19 45560
Molecular Formula : C17H27Cl2N
Molecular Weight : 316.31
stdClass Object
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[weight] => 302.28
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Desmethyl Sibutramine, Hydrochloride Salt
Catalogue No.:PA 19 45570
Molecular Formula : C16H25Cl2N
Molecular Weight : 302.28
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[weight] => 340.36
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(±)-Sibutramine-d6 HCl H2O (N,N-dimethyl-d6)
Catalogue No.:PA STI 088425
Molecular Formula : C17H23D6Cl2NO
Molecular Weight : 340.36
stdClass Object
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[catalogue_number] => PA 19 0761000
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[weight] => 251.80
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Catalogue No.:PA 19 0761000
Molecular Formula : C15H22ClN
Molecular Weight : 251.80
stdClass Object
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[weight] => 191.66
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1-(4-Chlorophenyl)cyclobutane carbonitrile
Catalogue No.:PA 19 0761001
Molecular Formula : C11H10ClN
Molecular Weight : 191.66
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[catalogue_number] => PA 19 0761002
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[weight] => 209.63
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3-(3-Chlorophenyl)-3-cyanopropanoic Acid
Catalogue No.:PA 19 0761002
Molecular Formula : C10H8ClNO2
Molecular Weight : 209.63
stdClass Object
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[weight] => 231.72
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2-(4-Chlorophenyl)-2-(prop- 2-en-1-yl)pent-4-enenitrile
Catalogue No.:PA 19 0761003
Molecular Formula : C14H14ClN
Molecular Weight : 231.72
stdClass Object
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[weight] => 260.2
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1-(1-(4-Chlorophenyl)cyclobutyl)-N,N-dimethylmethanamine Hydrochloride
stdClass Object
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[catalogue_number] => PA 19 0761005
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[weight] => 313.87
[form] => C20H24ClN
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Catalogue No.:PA 19 0761005
Molecular Formula : C20H24ClN
Molecular Weight : 313.87
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N,N,3-Trimethyl-1-(1-phenylcyclobutyl)butan-1-amine
Catalogue No.:PA 19 0761006
Molecular Formula : C17H27N
Molecular Weight : 245.41
stdClass Object
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[pname] => N-Formyl N,N-Didesmethyl Sibutramine
[catalogue_number] => PA 19 0761007
[category_ids] => ,80,78,70,82,
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[weight] => 279.81
[form] => C16H22ClNO
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N-Formyl N,N-Didesmethyl Sibutramine
Catalogue No.:PA 19 0761007
Molecular Formula : C16H22ClNO
Molecular Weight : 279.81