Spironolactone is used for the treatment of heart failures and kidney diseases. It is metabolised in liver and major metabolites of spironolactone are 7α-TMS,6β-OH-7α-TMS and canrenone,. Reference standards of Spironolactone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Spironolactone - Impurity F [catalogue_number] => PA 19 18060 [category_ids] => ,70,78,82,87, [chemical_name] => [weight] => 340.46 [form] => C22H28O3 [cas] => 976-71-6 [pslug] => 976-71-6-spironolactone-impurity-f-pa1918060 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18060
CAS :
Molecular Formula : C22H28O3
Molecular Weight : 340.46
stdClass Object ( [pname] => Spironolactone - Impurity I [catalogue_number] => PA 19 18090 [category_ids] => ,78,70,82,87, [chemical_name] => [weight] => 420.61 [form] => C24H36O4S [cas] => NA [pslug] => spironolactone-impurity-i-pa1918090 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18090
Molecular Formula : C24H36O4S
Molecular Weight : 420.61
stdClass Object ( [pname] => (2'R,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'(4'H)-one [catalogue_number] => PA 19 18510 [category_ids] => ,78,70,82,87, [chemical_name] => [weight] => 356.5 [form] => C23H32O3 [cas] => NA [pslug] => 2r-8r-9s-10r-13s-14s-3-methoxy-10-13-dimethyl-1-2-7-8-9-10-11-12-13-14-15-16-dodecahydro-3h-spiro-cyclopenta-a-phenanthrene-17-2-furan-5-4h-one-pa1918510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18510
Molecular Formula : C23H32O3
Molecular Weight : 356.5
stdClass Object ( [pname] => (2'S,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione [catalogue_number] => PA 19 18520 [category_ids] => ,78,70,82,87, [chemical_name] => [weight] => 340.46 [form] => C22H28O3 [cas] => NA [pslug] => 2s-8r-9s-10r-13s-14s-10-13-dimethyl-1-8-9-10-11-12-13-14-15-16-decahydro-3h-spiro-cyclopenta-a-phenanthrene-17-2-furan-3-5-2h-4h-dione-pa1918520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 18520
stdClass Object ( [pname] => Spironolactone-d6 (Major) [catalogue_number] => PA STI 079750 [category_ids] => ,98,78,70,82,87, [chemical_name] => [weight] => 422.61 [form] => C24H26D6O4S [cas] => NA [pslug] => spironolactone-d6-major-pasti079750 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 079750
Molecular Formula : C24H26D6O4S
Molecular Weight : 422.61
stdClass Object ( [pname] => Spironolactone-d3 [catalogue_number] => PA STI 079760 [category_ids] => ,98,78,70,82,87,88, [chemical_name] => [weight] => 419.59 [form] => C24H29D3O4S [cas] => NA [pslug] => spironolactone-d3-pasti079760 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 079760
Molecular Formula : C24H29D3O4S
Molecular Weight : 419.59
stdClass Object ( [pname] => 7α-Thiomethyl Spironolactone-d7 (Major) [catalogue_number] => PA STI 082790 [category_ids] => ,76,75,78,70,82,87,98, [chemical_name] => [weight] => 395.61 [form] => C23H25D7O3S [cas] => NA [pslug] => 7-alpha-thiomethyl-spironolactone-d7-major-pasti082790 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 082790
Molecular Formula : C23H25D7O3S
Molecular Weight : 395.61
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