| Catalogue number: | PA STI 041210 |
| Chemical name: | FK-506-13C,D2 (Major) (Tacrolimus) |
CAS Number: |
1356841-89-8 |
| Category: | pharmaceutical standards,intermediates,fine chemicals,stable isotopes |
| Synonyms: | Advagraf-13C,D2; FR 900506-13C,D2; Fujimycin-13C,D2; L 679934-13C,D2; Prograf-13C,D2; Protopic-13C,D2; TacroBell-13C,D2; Tacrolimus-13C,D2; Tsukubaenolide-13C,D2; |
| Molecular form: | C4313CH67D2NO12 |
| Appearance: | White to Off-White Solid |
| Mol. Weight: | 807.02 |
| Storage: | 2-8°C Refrigerator, Under Inert Atmosphere |
| Shipping Conditions: | Ambient |
| Applications: | A labelled immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. A representative lot contained a distribution of 20% d-1, 40% d-2 and 20% d-3. |
| BTM: | NA |
FK-506-13C,D2 (Major) (Tacrolimus)
FK-506-13C,D2 (Major) (Tacrolimus)
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